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铜绿假单胞菌噬菌体与宿主的相互作用研究进展

石茜 曾茁 张一鸣 杨子晨 彭毅志

石茜, 曾茁, 张一鸣, 等. 铜绿假单胞菌噬菌体与宿主的相互作用研究进展[J]. 中华烧伤与创面修复杂志, 2022, 38(9): 849-853. DOI: 10.3760/cma.j.cn501120-20210929-00338.
引用本文: 石茜, 曾茁, 张一鸣, 等. 铜绿假单胞菌噬菌体与宿主的相互作用研究进展[J]. 中华烧伤与创面修复杂志, 2022, 38(9): 849-853. DOI: 10.3760/cma.j.cn501120-20210929-00338.
Shi X, Zeng Z, Zhang YM,et al.Research advances on the interaction between Pseudomonas aeruginosa bacteriophages and the host[J].Chin J Burns Wounds,2022,38(9):849-853.DOI: 10.3760/cma.j.cn501120-20210929-00338.
Citation: Shi X, Zeng Z, Zhang YM,et al.Research advances on the interaction between Pseudomonas aeruginosa bacteriophages and the host[J].Chin J Burns Wounds,2022,38(9):849-853.DOI: 10.3760/cma.j.cn501120-20210929-00338.

铜绿假单胞菌噬菌体与宿主的相互作用研究进展

doi: 10.3760/cma.j.cn501120-20210929-00338
基金项目: 

国家自然科学基金面上项目 81772073

国家自然科学基金青年科学基金项目 82002051

创伤、烧伤与复合伤国家重点实验室开放课题基金 SKLKF201918

重庆市自然科学基金面上项目 cstc2021jcyj-msxmX0655

重庆市博士“直通车”项目 CSTB2022BSXM-JCX0019

详细信息
    通讯作者:

    彭毅志,Email:yizhipengtmmu@163.com

Research advances on the interaction between Pseudomonas aeruginosa bacteriophages and the host

Funds: 

General Program of National Natural Science Foundation of China 81772073

Youth Science Foundation Project of National Natural Science Foundation of China 82002051

Foundation of Open Projects from State Key Laboratory of Trauma, Burns and Combined Injury SKLKF201918

General Program of Natural Science Foundation of Chongqing cstc2021jcyj-msxmX0655

Chongqing Doctor "Through Train" Project CSTB2022BSXM-JCX0019

More Information
  • 摘要: 铜绿假单胞菌是最常见的烧伤感染创面病原菌,它能够编码多种毒力因子,具有很强的致病性,可导致预后差、病死率高。为了研究对抗铜绿假单胞菌感染的新方法,研究者们观察了其噬菌体与宿主之间广泛的相互作用。噬菌体通过多种机制影响甚至主导宿主细菌的结构、运动、代谢,促进宿主进化,也是影响宿主环境适应性和致病性的重要因素。该文分别从单细胞水平和群体水平对铜绿假单胞菌噬菌体与宿主的相互作用进行了综述。了解这些相互作用可为铜绿假单胞菌临床感染的治疗研究提供新的思路,为未来研发抗菌制剂以及指导烧伤感染治疗提供基础。

     

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  • 收稿日期:  2021-09-29

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