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2018 Vol. 34, No. 4

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Expert Forum
Lay emphasis on circulatory state research after fluid resuscitation in early burns
Zhang Qin, Tang Yaoqing
2018, 34(4): 193-196. doi: 10.3760/cma.j.issn.1009-2587.2018.04.001
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In this article, we discuss future development of circulatory state research after fluid resuscitation in early burns from its history and difficulties confronted. We believe that the Chinese fluid resuscitation formula to predict initial volume of fluid infusion of extensive burn patients is still ...
2018, 34(4): 196-196. doi: 10.3760/cma.j.issn.1009-2587.2018.04.101
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2018, 34(4): 196-196. doi: 10.3760/cma.j.issn.1009-2587.2018.04.103
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2018, 34(4): 196-196. doi: 10.3760/cma.j.issn.1009-2587.2018.04.102
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2018, 34(4): 202-202. doi: 10.3760/cma.j.issn.1009-2587.2018.04.104
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2018, 34(4): 240-242. doi: 10.3760/cma.j.issn.1009-2587.2018.04.009
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Critical Burn
Observation on safety and effects of analgesic and sedative treatment in severely burned patients during shock stage
Li Rubing, Chen Qian, Zhang Hongyan, Deng Hong′ao, Guo Guanghua, Mao Yuangui, Fu Zhonghua
2018, 34(4): 197-202. doi: 10.3760/cma.j.issn.1009-2587.2018.04.002
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Objective To observe the safety and effects of application of analgesic and sedative drugs in severely burned patients during shock stage. Methods One hundred and eighty patients with severe burns, conforming to the study criteria, were admitted to our unit from August 2014 to August 2016. Patients ...
Influencing factors and clinical significance of severe hypocalcemia in patients with extremely severe burns in early stage
Wu Jing, Zhang Qin, Liu Jian, Tang Jiajun, Zheng Jiexin
2018, 34(4): 203-207. doi: 10.3760/cma.j.issn.1009-2587.2018.04.003
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Objective To analyze the influencing factors and clinical significance of severe hypocalcemia in patients with extremely severe burns in early stage. Methods Clinical data of 142 patients with extremely severe burns admitted to our wards from January 2010 to July 2015, conforming to the study criter...
Dynamic variation trend and prognostic value of bronchial wall thickness in severely burned patients combined with inhalation injury
Wang Xin, Zhang Xuening, Wu Menglin, Jia Licong, Xie Li′na, Meng Yue, Feng Shihai, Ma Wei
2018, 34(4): 208-213. doi: 10.3760/cma.j.issn.1009-2587.2018.04.004
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Objective To explore the dynamic variation trend of bronchial wall thickness (BWT) in severely burned patients combined with inhalation injury, and to determine the value of BWT to prognosis of patients. Methods Forty-three severely burned patients with inhalation injury hospitalized in Intensive Bu...
Original Article
Effects of short chain fatty acid on barrier disruption of human intestinal epithelial cell induced by endotoxin/lipopolysaccharide and the related mechanism
Feng Yanhai, Huang Yalan, Wang Pei, Wang Fengjun
2018, 34(4): 214-218. doi: 10.3760/cma.j.issn.1009-2587.2018.04.005
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Objective To investigate the effects of short chain fatty acid (SCFA) on barrier disruption of human intestinal epithelial cell induced by endotoxin/lipopolysaccharide (LPS) and the related mechanism. Methods The human intestinal epithelial cell line Caco-2 was used to reproduce monolayer-cells. Cel...
Effects of exogenous high mobility group protein box 1 on angiogenesis in ischemic zone of early scald wounds of rats
Dai Lei, Guo Xing, Huang Haijun, Liao Xiaomei, Luo Xingqian, Li Dan, Zhou Hong, Gao Xiaochun, Tan Meiyun
2018, 34(4): 219-224. doi: 10.3760/cma.j.issn.1009-2587.2018.04.006
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Objective To observe effects of exogenous high mobility group protein box 1 (HMGB1) on angiogenesis in ischemic zone of early scald wounds of rats. Methods Thirty-six Sprague-Dawley rats were divided into HMGB1 group and simple scald (SS) group according to the random number table, with 18 rats in e...
Antiseptic effect of compound lysostaphin disinfectant and its preventive effect on infection of artificial dermis after graft on full-thickness skin defect wound in rats
Jin Jian, Zhou Hao, Cui Zhenci, Wang Li, Luo Pengfei, Ji Shizhao, Hu Xiaoyan, Ma Bing, Wang Guangyi, Zhu Shihui, Xia Zhaofan
2018, 34(4): 225-232. doi: 10.3760/cma.j.issn.1009-2587.2018.04.007
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Objective To study the antiseptic effect of compound lysostaphin disinfectant and its preventive effect on infection of artificial dermis after graft on full-thickness skin defect wound in rats. Methods (1) Each one standard strain of Klebsiella pneumoniae, Acinetobacter baumannii, and Staphylococcu...
Application of recombinase polymerase amplification in the detection of Pseudomonas aeruginosa
Jin Xiaojun, Gong Yali, Yang Li, Mo Banghui, Peng Yizhi, He Peng, Zhao Junning, Li Xiaolu
2018, 34(4): 233-239. doi: 10.3760/cma.j.issn.1009-2587.2018.04.008
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Objective To establish an optimized method of recombinase polymerase amplification (RPA) to rapidly detect Pseudomonas aeruginosa in clinic. Methods (1) The DNA templates of one standard Pseudomonas aeruginosa strain was extracted and detected by polymerase chain reaction (PCR), real-time fluorescen...
Review
Advances in the research of biomechanical effects of negative-pressure wound therapy in promoting wound healing
Chen Xiaoqiang, Zhang Wei, Li Xueyong
2018, 34(4): 243-246. doi: 10.3760/cma.j.issn.1009-2587.2018.04.010
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Recently, researchers have focused on the micro-mechano-environment and the resulting mechanical cues which can regulate the morphology, structure, and function of cells. As a novel mechanotherapy, negative-pressure wound therapy (NPWT) has revolutionized the treatment of acute and chronic wounds. T...
Advances in the research of application of artificial intelligence in burn field
Li Haihang, Bao Zhenxing, Liu Xiaobin, Zhu Shihui
2018, 34(4): 246-248. doi: 10.3760/cma.j.issn.1009-2587.2018.04.011
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Artificial intelligence has been able to automatically learn and judge large-scale data to some extent. Based on database of a large amount of burn data and in-depth learning, artificial intelligence can assist burn surgeons to evaluate burn surface, diagnose burn depth, guide fluid supply during sh...
Advances in the research of effects of glutamine on immune function of burn patients
Liu Yanhua, Guo Pengfei, Chen Gaiyun, Bo Yacong, Ma Yan, Cui Zhengjun
2018, 34(4): 249-253. doi: 10.3760/cma.j.issn.1009-2587.2018.04.012
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Glutamine is the most abundant amino acid found in plasma and cells. It is the preferred fuel for enterocytes in the small intestine, macrophages, and lymphocytes. After serious burn, increased requirement of glutamine by the gastrointestinal tract, kidney and lymphocytes, and relatively insufficien...
Advances in application of clustered regularly interspaced short palindromic repeats (CRISPR)/CRISPR-associated 9 system in stem cells research
Sun Sujing, Huo Jiahui, Geng Zhijun, Sun Xiaoyan, Fu Xiaobing
2018, 34(4): 253-256. doi: 10.3760/cma.j.issn.1009-2587.2018.04.013
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Gene engineering has attracted worldwide attention because of its ability of precise location of disease mutations in genome. As a new gene editing technology, clustered regularly interspaced short palindromic repeats (CRISPR)/CRISPR-associated 9 (Cas9) system is simple, fast, and accurate to operat...

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