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2019 Vol. 35, No. 1

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A Letter from the Editor-in-Chief
Set sail again and look forward to new 60 years
Peng Yizhi
2019, 35(1): 1-2. doi: 10.3760/cma.j.issn.1009-2587.2019.01.001
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Abstract:
The outstanding work of Chinese Journal of Burns in 2018: the successful planning and display of the " Burn Medicine Over the Past 60 Years" column, the launch of seven guidelines and consensus for burn injury treatment, and the opening of the " Online First" and " Video Center" sections in the jour...
Academician Forum
Role of cytokines in sepsis and its current situation of clinical application
Xia Zhaofan, Wu Guosheng
2019, 35(1): 3-7. doi: 10.3760/cma.j.issn.1009-2587.2019.01.002
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Sepsis is defined as a life-threatening organ dysfunction caused by a dysregulated host response to infection, which is a global health crisis. The cytokines are a class of protein mediators secreted by cells with low molecular weights and biological activity. There are two types of cytokines, pro-i...
Expert Forum
Developing trend of wound dressing
Huan Jingning
2019, 35(1): 8-11. doi: 10.3760/cma.j.issn.1009-2587.2019.01.003
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The ideal wound dressing should have the functions of keeping wound moist and warm, preventing and treating wound infection, promoting wound healing, and so on; However there is no such ideal wound dressing in clinic. Dressings are likely to capable application to different kinds of wounds with mult...
Original Article·New Technology and Dressing of Wound Treatment
Content characteristics and cytotoxicity detection of silver ion products
Su Xuerong, Gan Junying, Xue Yuying, Li Qiang
2019, 35(1): 12-17. doi: 10.3760/cma.j.issn.1009-2587.2019.01.004
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Objective To analyze the silver content, homogeneity, and cytotoxicity of silver-containing products. Methods (1) Five kinds of silver-containing products A, B, C, D, and E were purchased from the market, and products A, B, C, and D are liquid or gel form while product E was dressing form. The silve...
Analysis of differential gene expressions of inflammatory and repair-related factors in chronic refractory wounds in clinic
Wang Lian, Guo Fei, Min Dinghong, Liao Xincheng, Yu Shaoqing, Long Xingxing, Ding xiang, Guo Guanghua
2019, 35(1): 18-24. doi: 10.3760/cma.j.issn.1009-2587.2019.01.005
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Objective To compare the tissue morphology and gene expressions of inflammatory and repair-related factors in chronic refractory wound tissue including pressure ulcers and diabetic feet. Methods During August 2016 to September 2017, 10 samples of prepuce were collected after circumcision of 10 urolo...
Clinical characteristics and treatment of diabetic patients with superficial partial-thickness burn on feet
Ling Xiangwei, Zhang Tingting, Dai Wentong, Xia Weidong, Lin Cai
2019, 35(1): 25-30. doi: 10.3760/cma.j.issn.1009-2587.2019.01.006
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Objective To analyze the characteristics and treatment of diabetic patients with superficial partial-thickness burn on feet. Methods Eighty-three patients with superficial partial-thickness burn on 119 feet were hospitalized in our unit from January 2011 to December 2017. The medical records of the ...
Effects of platelet-rich plasma combined with polylactic acid/polycaprolactone on healing of pig deep soft tissue defect caused by fragment injury
Yao Dan, Hao Daifeng, Zhao Fan, Hao Xiufeng, Feng Guang, Chu Wanli, Chen Zequn
2019, 35(1): 31-39. doi: 10.3760/cma.j.issn.1009-2587.2019.01.007
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Objective To investigate the effects of platelet-rich plasma (PRP) combined with polylactic acid/polycaprolactone (PLA/PCL) on healing of mininature pig deep soft tissue defect caused by fragment injury. Methods Two male Bama miniature pigs with 11 to 12 months (the same below) were selected by lott...
Effects of adipose-derived mesenchymal stem cells from type 2 diabetes mellitus patients on wound healing of pressure ulcers in mice
Deng Chengliang, Yao Yuanzhen, Liu Zhiyuan, Wang Bo, Wang Dali, Wei Zairong
2019, 35(1): 40-47. doi: 10.3760/cma.j.issn.1009-2587.2019.01.008
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To investigate the effects of adipose-derived mesenchymal stem cells (AMSCs) from type 2 diabetes mellitus patients on wound healing of pressure ulcers in mice. Methods (1) In September 2016, the subcutaneous adipose tissue of a 60-year-old woman with type 2 diabetes mellitus was harvested, and then...
Original Article
Effects of platelet-rich plasma on the survival of ultra-long dorsal random flaps in rats
Tian Xinli, Jiang Bo, Yan Hong
2019, 35(1): 48-53. doi: 10.3760/cma.j.issn.1009-2587.2019.01.009
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Objective To observe the effects of platelet-rich plasma (PRP) on the survival of ultra-long dorsal random flaps in rats. Methods Sixteen male Sprague Dawley rats aged 6 to 8 weeks (the same below) were sacrificed to collect whole blood of 9 to 10 mL from each rat, and PRP was prepared by modified A...
Protective effects and mechanism of keratinocyte growth factor combined with hypoxia inducible factor-1α on intestinal crypt epithelial cells of rats with hypoxia stress
Xu Qian, Bai Yanqing, Zeng Tongxu, Yang Bo, Cai Xiaoling, Ha Xiaoqin
2019, 35(1): 54-61. doi: 10.3760/cma.j.issn.1009-2587.2019.01.010
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Objective To investigate the protective effects and mechanism of keratinocyte growth factor (KGF) combined with hypoxia inducible factor-1α (HIF-1α) on intestinal crypt epithelial cells (IEC-6) of rats with hypoxia stress. Methods (1) The routinely cultured IEC-6 of rats were collected and divided i...
2019, 35(1): 61-61. doi: 10.3760/cma.j.issn.1009-2587.2019.01.101
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Brief Original Article
Effects of free superficial temporal fascia flaps and skin grafts in repairing deep wounds in posterior ankle region of extensively burned patients
Yang Xuekang, Chen Qiaohua, Zhang Yue, Li Zhiqiang, Tao Ke, Han Juntao, Hu Dahai
2019, 35(1): 62-64. doi: 10.3760/cma.j.issn.1009-2587.2019.01.011
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Objective To observe the effects of the method of combining free superficial temporal fascia flaps with skin grafts in repairing deep wounds in posterior ankle region of extensively burned patients. Methods From September 2013 to February 2017, 11 extensively burned patients with deep tissue defects...
Clinical effects of perforating branch flaps of medial vastus muscle in repairing secondary wounds in donor sites of free anterolateral femoral perforator flaps
Gao Qiufang, Zhang Xiaofeng, Zhang Wanfeng, Ma Bin, Niu Xuetao, Ma Yajun, Li Zibiao, Liu Ning
2019, 35(1): 65-68. doi: 10.3760/cma.j.issn.1009-2587.2019.01.012
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Objective To investigate the clinical effects of perforating branch flaps of medial vastus muscle in repairing secondary wounds in donor sites of free anterolateral femoral perforator flaps. Methods From August 2014 to December 2016, 12 patients (8 males and 4 females, aged 35-72 years) with skin an...
Case Report
One case of pyoderma gangrenosum in the lower limbs in Tibetan Plateau treated with vacuum sealing drainage combined with irrigation of oxygen loaded fluid
Yang Sisi, Jiang Shuguo, Tudeng Cicheng, Ni zhen, Xiao Chengzhi
2019, 35(1): 69-71. doi: 10.3760/cma.j.issn.1009-2587.2019.01.013
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A 54 years old male patient with chronic leg ulcers was admitted in our hospital in November 2017. He was diagnosed as pyoderma gangrenosum by the pathological examination. Then the wound was treated with simple vacuum sealing drainage combined with irrigation of oxygen loaded fluid. This therapy ov...
Acquired blood coagulation factor Ⅴ deficiency in a patient with severe burn
Bi Xiaojie, Jin Xianfu, Zhang Huifei, Su Zhengxian, Shen Bo
2019, 35(1): 71-73. doi: 10.3760/cma.j.issn.1009-2587.2019.01.014
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In March 2017, a severely burned male patient aged 36 years with hypovolemic shock was admitted to our hospital. The patient received large quantities of antibiotics and blood products and repeated skin graft after admission, and then he suffered wound errhysis and throat congestion. The patient was...
Review
Advances in the research of transcatheter arterial thrombolysis for severe frostbite therapy
Zhang Jinlong, Fu Jinxin, Yuan Kai, Yuan Bing, Wang Maoqiang
2019, 35(1): 74-76. doi: 10.3760/cma.j.issn.1009-2587.2019.01.015
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Severe frostbite (grade Ⅲ to Ⅳ) is a common disease accompanied with high disability rate in cold regions, especially for military training and disaster events in cold regions. The treatment of severe frostbite mainly includes rapid rewarming in the early stage and amputation in the later stage; whi...
Advances in exosomes derived from the mesenchymal stem cells in the treatment of sepsis
Wang Shan, Yin Haiyan
2019, 35(1): 77-80. doi: 10.3760/cma.j.issn.1009-2587.2019.01.016
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Exosomes derived from mesenchymal stem cells (MSCs) are small membrane vesicles with diameters in 30-150 nm, which are secreted into extracellular matrix by MSCs in resting or activated state. Recent studies have found that exosomes secreted by MSCs can be used as important signal transduction media...

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