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2019 Vol. 35, No. 10

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Guidelines and Consensuses
Experts consensus on clinical application of bilayer artificial dermis (2019 version)
Writing group of experts consensus on clinical application of bilayer artificial dermis (2019 version)
2019, 35(10): 705-711. doi: 10.3760/cma.j.issn.1009-2587.2019.10.001
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Artificial dermis is a kind of tissue engineering dermal substitute and is used to repair dermal defects caused by a variety of reasons. This article describes the characteristics and the mechanism of repair and reconstruction of bilayer artificial dermis. Based on domestic experience of clinical ap...
Expert Forum
Scar management strategy in children
Qi Hongyan
2019, 35(10): 712-714. doi: 10.3760/cma.j.issn.1009-2587.2019.10.002
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Children are a special group, which have unique physiological characteristics and are still in the period of physical and mental growth and development, thus the prevention and treatment of scar in children are different from that in adults. Scar management in children is a complex and multifaceted ...
Original Article • Pediatric Burn
Application effects of enhanced computed tomography and three-dimensional reconstruction technology in reconstruction of pediatric post-burn scars with expanded flaps
Liu Lei, Wang Yanni, Yu Jing, Qi Hongyan
2019, 35(10): 715-719. doi: 10.3760/cma.j.issn.1009-2587.2019.10.003
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Objective To explore the application effects of enhanced computed tomography (CT) and three-dimensional reconstruction technology in the reconstruction of pediatric post-burn scars with expanded flaps. Methods From May 2016 to March 2019, 19 children with hypertrophic scars after thermal injuries we...
Preliminary effect observation on the application of micro-negative pressure in children with small-area deep partial-thickness burn
Zheng Xiaopeng, Chen Jue, Chen Tiansheng, Jiang Yaonan, Shen Tuo, Xiao Shichu, Hu Xiaoyan
2019, 35(10): 720-725. doi: 10.3760/cma.j.issn.1009-2587.2019.10.004
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Objective To preliminarily observe the effects of application of micro-negative pressure in children with small-area deep partial-thickness burn. Methods From January 2016 to August 2018, 64 children with small-area deep partial-thickness burn who were admitted to the Department of Burn Surgery of t...
Clinical randomized controlled trial on influence of recombinant human growth hormone on the immune function of younger children with severe burn injuries
Mei Ailian, Qiu Lin, Zhang Yue, Yuan Xingang, Liu Yan, Li Tianwu, Ding Xionghui
2019, 35(10): 726-732. doi: 10.3760/cma.j.issn.1009-2587.2019.10.005
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Objective To preliminarily investigate the influence of recombinant human growth hormone (rhGH) on the immune function of younger children with severe burn injuries. Methods A total of 30 younger children with severe burn injuries, conforming to the study criteria, were admitted to our hospital from...
2019, 35(10): 725-725. doi: 10.3760/cma.j.issn.1009-2587.2019.10.101
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2019, 35(10): 732-732. doi: 10.3760/cma.j.issn.1009-2587.2019.10.102
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2019, 35(10): 739-739. doi: 10.3760/cma.j.issn.1009-2587.2019.10.103
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2019, 35(10): 745-745. doi: 10.3760/cma.j.issn.1009-2587.2019.10.104
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2019, 35(10): 756-756. doi: 10.3760/cma.j.issn.1009-2587.2019.10.105
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Original Article
Preliminary study on effect of intraoperative goal-directed fluid management on pulmonary function and oxygen dynamics in patients with severe burns
Wang Ziwei, Chen Yan, Cheng Fujun, Chen Xingqi, Yang Yong, Lu Kaizhi
2019, 35(10): 733-739. doi: 10.3760/cma.j.issn.1009-2587.2019.10.006
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Objective To preliminarily investigate the effect of intraoperative goal-directed fluid management (GDFM) on pulmonary function and oxygen dynamics in patients with severe burns. Methods From February 2017 to May 2018, 30 patients admitted to Burn Department of our hospital with severe burns who met...
Construction and identification of mouse model with conditional knockout of p75 neurotrophin receptor gene in epidermal cells by Cre-loxP system
Sun Rui, Cao Yongqian, Ma Jiaxu, Yin Siyuan, Zhang Min, Song Ru, Jiang Hang, Gao Yan, Zhang Huayu, Feng Zhang, Liu Jian, Liu Zhenxing, Wang Yibing
2019, 35(10): 740-745. doi: 10.3760/cma.j.issn.1009-2587.2019.10.007
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Objective To construct and identify a mouse model with conditional knockout (cKO) of p75 neurotrophin receptor (p75NTR-cKO) gene in epidermis cells by Cre-loxP system. Methods Five p75NTRflox/flox transgenic C57BL/6J mice (aged 6-8 weeks, male and female unlimited, the age and sex of mice used for r...
Protein expressions of matrix metalloproteinase-9 and its inhibitor and their ratio changes in wound healing of patients with stages Ⅲ and Ⅳ pressure ulcers
Wang Yue, Li Xian, Zhao Wei, Gao Zhanhong, Zheng Meijie, Pang Yuling, Chen Ziye
2019, 35(10): 746-751. doi: 10.3760/cma.j.issn.1009-2587.2019.10.008
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Objective To explore the expression levels of matrix metalloproteinase-9 (MMP-9) and tissue inhibitor of metalloproteinase-1 (TIMP-1) protein and the change of MMP-9/TIMP-1 ratio in wound exudates of patients with stages Ⅲ and Ⅳ pressure ulcers during wound healing. Methods From July 2017 to July 20...
Application of Plato analysis combined with plan-do-check-act cycle in scientific research management of nurses with primary position title
Lu Ying, Zhou Qin, Wang Lina, Wang Dongjuan, Wang Ni, Hou Jiao, Wang Qing, Xue Jiao
2019, 35(10): 752-756. doi: 10.3760/cma.j.issn.1009-2587.2019.10.009
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Objective To explore the effects of application of Plato analysis combined with plan-do-check-action (PDCA) cycle in scientific research management of nurses with primary position title. Methods Twenty-six nurses with primary position title were recruited in this self pre- and post-control study. Fr...
Brief Original Article
Clinical therapeutic observation on sequential treatment of chronic wounds with repeated recurrence of hidradenitis suppurativa in buttocks
Li Zhiqing, Wen Huangding, Li Shenglong, Niu Libin, Wu Qi
2019, 35(10): 757-760. doi: 10.3760/cma.j.issn.1009-2587.2019.10.010
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Objective To observe the clinical effects of sequential treatment with extensive lesion resection, vacuum sealing drainage (VSD) combined with irrigation of oxygen-loaded fluid, and tissue transplantation on hidradenitis suppurativa (HS) in buttocks which recurred after multiple surgeries. Methods F...
Experience Exchange
Transplantation of compound tissue flap of toe to reconstruct the thumb with necrosis caused by electric burns in four patients
Cao Shengjun, Wang Lingfeng, Ba Te, Rong Zhidong, Hu Guolin, Zhou Biao, Li Quan, Yan Zengqiang
2019, 35(10): 761-763. doi: 10.3760/cma.j.issn.1009-2587.2019.10.011
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From January 2010 to December 2017, 4 patients of thumb with necrosis caused by electric burns (all male, aged from 31 to 58 years) were admitted to our hospital, with 1 patient of second degree injury of right thumb, 2 patients of third degree injury of right thumb, and 1 patient of third degree in...
Review
Advances in the research of effects of mesenchymal stem cells, exosomes, and platelet-rich plasma in wound repair
Li Fang, Li Quan, Wang Lingfeng
2019, 35(10): 764-768. doi: 10.3760/cma.j.issn.1009-2587.2019.10.012
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Due to difficult healing, wounds become chronic diseases in many patients, and bring heavy burden to family and society in China. Although there are many studies about wound repair at present, its mechanism remains unclear. An increasing number of studies showed that mesenchymal stem cells (MSCs), e...

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