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2019 Vol. 35, No. 3

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Expert Comment
Emphasis on the exploration and research of the protective strategy of organs after burns in the early stage
Wang Yibing
2019, 35(3): 161-162. doi: 10.3760/cma.j.issn.1009-2587.2019.03.001
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Abstract:
Objective A series of pathophysiological changes occur in a body with burn, among which the pathophysiological changes in organs are rather insidious but have far-reaching effects. At present, in clinical practice, we mainly adopt symptomatic or alternative treatment to deal with organ dysfunction, ...
Original Article · Organ Injury and Treatment and Protection in Early Stage of Burn
Retrospective study on the characteristics of early organ injury in elderly patients with severe burns
Wang Wensheng, Xiang Fei, Song Huapei, Zhang Can, Zhang Bingqian, Lyu Yanling, Yuan Hongping, Hu Gaozhong, Huang Yuesheng
2019, 35(3): 163-168. doi: 10.3760/cma.j.issn.1009-2587.2019.03.002
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Objective To analyze the clinical characteristics of early organ injury in elderly patients with severe burns and the effects on the prognosis of patients. Methods From January 2010 to August 2018, 62 patients with severe burns (43 men and 19 women, aged from 60 to 89 years at the time of admission)...
In vitro study of the effect of human antigen R on lysosomal acidification during autophagy in mouse cardiomyocytes
Lin Jiezhi, Yi Ruofan, Zhang Xingyue, Jia Jiezhi, Zhang Qiong, Cui Lin, Yang Lei, Ye Jingying, Zhang Dongxia, Lyu Yanling, Huang Yuesheng
2019, 35(3): 169-178. doi: 10.3760/cma.j.issn.1009-2587.2019.03.003
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Objective To investigate the effect of human antigen R on lysosomal acidification during autophagy in mouse cardiomyocytes cultured in vitro. Methods The hearts of 20 C57BL/6 mice aged 1-2 days no matter male or female were isolated to culture primary cardiomyocytes which were used in the following ...
Effects of different doses of dopamine on organ function of rats at early stage of severe scald
Wang Zi′en, Wang Shunbin, Chen Zhaohong
2019, 35(3): 179-185. doi: 10.3760/cma.j.issn.1009-2587.2019.03.004
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Objective To explore the effects of different doses of dopamine on organ function of rats at early stage of severe scald. Methods Thirty-two male Wistar rats aged 8 to 12 weeks were divided into sham injury (SI) group, simple resuscitation (SR) group, small dose (SD) group, and moderate dose (MD) gr...
In vitro study of effects of transient receptor potential vanilloid 1 on autophagy in early hypoxic mouse cardiomyocytes and the mechanism
Wei Jinyu, Cui Lin, Lin Jiezhi, Zhang Qiong, Yuan Hongping, Xiang Fei, Song Huapei, Jia Jiezhi, Lyu Yanling, Zhang Dongxia, Huang Yuesheng
2019, 35(3): 186-192. doi: 10.3760/cma.j.issn.1009-2587.2019.03.005
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Objective To explore the effects of transient receptor potential vanilloid 1 (TRPV1) on autophagy in early hypoxic mouse cardiomyocytes and the mechanism in vitro. Methods The hearts of 120 C57BL/6 mice aged 1-2 days, no matter male or female, were isolated, and then primary cardiomyocytes were cult...
Original Article
Effects of transcutaneous electrical acupoint stimulation on pain of patients in expansion process of skin soft tissue dilator on forehead by water injection
Huang Ying, Bian Weiwei, Hou Lili
2019, 35(3): 193-197. doi: 10.3760/cma.j.issn.1009-2587.2019.03.006
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Objective To explore the effects of transcutaneous electrical acupoint stimulation (TEAS) on pain of patients in expansion process of skin soft tissue dilator on forehead by water injection. Methods From June 2016 to June 2017, 100 patients in expansion process of skin soft tissue dilator on forehea...
Cognitive level of first aid knowledge regarding small area burn among 2 723 child caregivers in Shanghai: a cross-sectional survey and analysis
Yu Qing, Xiao Yongqiang, Hu Xiaoyan, Xia Zhaofan
2019, 35(3): 198-204. doi: 10.3760/cma.j.issn.1009-2587.2019.03.007
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Objective To assess the cognitive level of first aid knowledge regarding the small area burn among the child caregivers in Shanghai and improve the level of first aid for small area burn in children. Methods From November 2017 to March 2018, 7 municipal districts in Shanghai were selected according ...
Effects of free mini-flap on tibial side of third toe on repairing skin and soft tissue defect of finger pulp at the end of finger
Zhou Jian, Wei Zairong, Sun Guangfeng, Jin Wenhu, Chang Shusen, Li Hai, Nie Kaiyu, Tang Xiujun, Gong Feiyu
2019, 35(3): 205-208. doi: 10.3760/cma.j.issn.1009-2587.2019.03.008
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Objective To investigate the effects of free mini-flap on tibial side of third toe on repairing skin and soft tissue defect of finger pulp at the end of finger. Methods From August 2013 to May 2017, 18 patients with skin and soft tissue defect of finger pulp at the end of finger were admitted to our...
Regulation of hypoxia inducible factor-1α on permeability of vascular endothelial cells and the mechanism
Hu Delin, Yu Youxin, Liang Rong, Zhou Shunying, Duan Shengliang, Jiang Zhiyong, Meng Chengying, Jiang Wei, Wang Huan, Sun Yexiang, Fang Linsen
2019, 35(3): 209-217. doi: 10.3760/cma.j.issn.1009-2587.2019.03.009
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Objective To investigate the regulation of hypoxia-inducible factor-1α (HIF-1α) on permeability of rat vascular endothelial cells and the mechanism. Methods Twelve male Sprague-Dawley rats aged 35 to 38 days were collected and vascular endothelial cells were separated and cultured. The morphology of...
Brief Original Article
Clinical effects of heel lateral flap in repair of skin and soft tissue defects at posterior heel region
Jin Wenhu, Chang Shusen, Wei Zairong, Li Hai, Zhou Jian, Chen Wei, Sun Guangfeng, Tang Xiujun, Wang Bo
2019, 35(3): 218-220. doi: 10.3760/cma.j.issn.1009-2587.2019.03.010
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Objective To explore the clinical effects of heel lateral flap in repair of skin and soft tissue defects at posterior heel region. Methods From September 2007 to April 2016, 24 patients (17 males and 7 females, aged 16-70 years) with skin and soft tissue defects at posterior heel region were admitte...
Experience Exchange
Five patients with severe burns complicated by fungal infection
Fan Youfen, Chen Cui, Li Jiliang, Huang Neng, Cui Shengyong
2019, 35(3): 221-223. doi: 10.3760/cma.j.issn.1009-2587.2019.03.011
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From June to November 2016, 5 patients with severe burns were admitted to our unit. Broad-spectrum antibiotic and fluconazole were used on patients as earlier empirical anti-infection therapy of bacteria and fungi. Seven to twenty-one days after injury, 5 patients developed fungal infection. Antifun...
Case Report
One case of refractory gout with high fever
Xu Pei, Long Zhongheng, Zhang Xiangming, Liu Xiaoqin, Xie Weiguo
2019, 35(3): 224-227. doi: 10.3760/cma.j.issn.1009-2587.2019.03.012
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On 17th June 2017, a 50 years old man with refractory gout was admitted in our hospital. During the treatment, he was accompanied by intermittent fever (39 to 40 ℃) of unknown origin for 60 days and gastrointestinal bleeding, with difficult wound repair. After comprehensive treatment of thorough deb...
Bilateral internal jugular vein thrombosis in a patient with severe burn
Wu Choulang, Zhou Lichun, Pan Juntai
2019, 35(3): 227-228. doi: 10.3760/cma.j.issn.1009-2587.2019.03.013
Abstract
Abstract:
A 33 years old male patient who suffered from a flame burn of 88% total body surface area was admitted to our hospital on November 28th, 2016. During his hospitalization, we repeatedly performed central vein catheterization in internal jugular veins, subclavian veins, or femoral veins for fluid tran...
Review
Advances in the research of early deepening mechanism and prevention measures of burn wounds
Lai Qinghong, Zhang Youlai, Xin Guohua
2019, 35(3): 229-232. doi: 10.3760/cma.j.issn.1009-2587.2019.03.014
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Deepening of wounds not only prolongs the wound repair time, increases the chance of scar formation after healing, but also is one of the important causes of death in severe burn patients. How to prevent wound deepening is a clinical problem in the treatment of burns. The mechanism of deepening burn...
Advances in the research of autologous fat grafting in the prevention and treatment of scar
Fang Lu, Chen Junjie, Cen Ying
2019, 35(3): 233-236. doi: 10.3760/cma.j.issn.1009-2587.2019.03.015
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Scars formed by various injuries can affect the appearance and psychology of patients. Therefore, more and more people pay attention to the prevention and treatment of scar. With the development of the autologous fat grafting, it has been gradually applied to the prevention and treatment of scar. At...
Advances in the research of sensory nerve regeneration in tissue engineering skin
Zhu Zhikang, Wu Pan, Wang Xingang, Han Chunmao
2019, 35(3): 237-240. doi: 10.3760/cma.j.issn.1009-2587.2019.03.016
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Severe skin damage not only causes a mass of tissue defect, but also leads to the loss of various sensory functions. Tissue engineering skin provides a new way for high-quality wound repair, while there are still many problems in the recovery of sensory function, such as abnormality or loss of sensa...

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