2021 Vol. 37, No. 7

2021, 37(7): F01-F01. doi: 10.3760/cma.j.issn.1009-2587.2021.07.101
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2021, 37(7): 634-634. doi: 10.3760/cma.j.issn.1009-2587.2021.07.102
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2021, 37(7): 701-701. doi: 10.3760/cma.j.issn.1009-2587.2021.07.103
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2021, 37(7): 702-704. doi: 10.3760/cma.j.cn501120-20210712-00245
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Expert Forum
Discussions on the causes and evaluation of mangled injury and the optimization of its repair strategy
Zhang Pihong
2021, 37(7): 601-605. doi: 10.3760/cma.j.cn501120-20210119-00029
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Many reasons can cause damage to a certain part of body, with the damaged tissue showing some corresponding characteristics. There are many uncertainties in the repair of damaged body parts, making it difficult to achieve the ideal function and appearance. In recent years, the repair of mangled inju...

Original Articles·Mangled Wound
Application strategy and clinical effects of paraumbilical perforator flap with inferior epigastric vessels in repairing destructive wounds
Qin Fengjun, Shen Yuming, Du Weili, Cheng Lin, Zhang Ying, Ma Chunxu
2021, 37(7): 606-613. doi: 10.3760/cma.j.cn501120-20210310-00082
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Objective To explore the application strategy and clinical effects of paraumbilical perforator flap with inferior epigastric vessels in repairing various destructive wounds. Methods The retrospective observational study method was applied. From January 2015 to December 2020, 28 patients (21 males an...

Repair methods and clinical effects of full-thickness burn wounds deep to tendon or even bone in fingers
Liang Pengfei, Zhang Pihong, Zhang Minghua, Zeng Jizhang, Zhou Jie, Huang Mitao, Cui Xu, Guo Le, Yan Zhuoxian, Ran Yanqin, Zhou Situo, He Zhiyou, Huang Xiaoyuan
2021, 37(7): 614-621. doi: 10.3760/cma.j.cn501120-20210114-00020
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Objective To explore the repair methods and clinical effects of full-thickness burn wounds deep to tendon or even bone in fingers. Methods A retrospective non-randomized controlled trial was conducted on the 98 patients with full-thickness finger burns deep to tendon or even bone who met the inclusi...

Clinical application effect of latissimus dorsi muscle flap in reconstruction of muscle strength around shoulder after electric burns
Zhang Wanfu, Xu Jing, Hu Xiaolong, Han Fei, Tong Lin, Li Shaohui, Xiang Shengtao, Guan Hao
2021, 37(7): 622-628. doi: 10.3760/cma.j.cn501120-20210329-00107
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Objective To investigate the clinical application effect of latissimus dorsi muscle flap in reconstruction of muscle strength around shoulder after electric burns. Methods From March 2014 to September 2020, 13 patients with electric burns and severe injury around shoulder were admitted to the First ...

Original Article
Transepidermal water loss of scar skin in three types of scar patients and its correlation with scar severity
Fan Hua, Zhang Jiuwen, Liu Dujuan, Liu Fengbin
2021, 37(7): 629-634. doi: 10.3760/cma.j.cn501120-20200310-00145
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Objective To study the transepidermal water loss (TEWL) of scar skin in patients with superficial scars, hypertrophic scars, and atrophic scars, and to explore the correlation between TEWL and scar severity. Methods A retrospective observational study was conducted. From February 2017 to February 20...

Clinical effects of ulnar artery perforator chain flaps in repairing wounds on distal forearm or wrist with vascular anastomosis
Wang Hui, Yang Xiaoxi, Huo Yongxin, Qin Haoyu, Wang Wei, Wang Bin, Jiang Wenping
2021, 37(7): 635-639. doi: 10.3760/cma.j.cn501120-20200422-00234
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Objective To investigate the clinical effects of ulnar artery perforator chain flaps in repairing wounds on distal forearm or wrist with vascular anastomosis. Methods The retrospective observational study method was used. From March 2015 to July 2019, a total of 11 serious trauma patients on distal ...

Roles of adenosine monophosphate activated protein kinase in skeletal muscle atrophy in rats with severe scald
Deng Huping, Cai Jianhua, Chai Jiake, Shen Chuan'an, Li Ligen, Sun Tianjun, Chen Jingjing, Li Dongjie, Dong Ning, Liu Lingying
2021, 37(7): 640-646. doi: 10.3760/cma.j.cn501120-20200416-00227
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Objective To investigate the expression and phosphorylation level change of adenosine monophosphate activated protein kinase (AMPK) in skeletal muscle of severely scald rats and its roles in skeletal muscle atrophy in severely scalded rats. Methods The experimental research method was applied. Total...

Roles of interleukin-6/signal transduction and activator of transcription 3 pathway and β-catenin in mechanical stress-induced hypertrophic scar formation in mice
Shi Lulu, Zhang Rufeng, Xiao Hu
2021, 37(7): 647-653. doi: 10.3760/cma.j.cn501120-20200417-00231
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Objective To establish mechanical stress-induced hypertrophic scar mouse models, and to examine the roles of interleukin-6/signal transduction and activator of transcription 3 (IL-6/STAT3) pathway and β-catenin. Methods The experimental research method was used. Sixteen female C57/BL6 mice of 12-wee...

Systematic review of the epidemiological characteristics of inhalation injury in burn patients in China
Dou Zhe, Zhang Guo'an
2021, 37(7): 654-660. doi: 10.3760/cma.j.cn501120-20200306-00129
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Objective To study the epidemiological characteristics of inhalation injury in burn patients in China. Methods The systematic review method was performed.Chinese Journal Full-text Database,Wanfang Database,andChineseBiomedical Literature Database were searched with the Chinese search terms of "吸入性损伤...

Hair Follicle Transplantation
Clinical effects of fine follicular unit extraction and transplantation in repairing cicatricial eyebrow defects
Xue Ping, Song Baoqiang, Fan Xing, Dou Wenjie
2021, 37(7): 661-665. doi: 10.3760/cma.j.cn501120-20200316-00172
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Objective To observe the clinical effects of fine follicular unit extraction (FUE) and transplantation in repairing cicatricial eyebrow defects. Methods The retrospective observational study was conducted. From September 2013 to January 2020, 58 patients (36 males and 22 females, aged 12-40 years) u...

Technique and Method
Advice on the rationalized layout of outpatient clinics in a wound repair department
Zhou Ming, Wang Chunlan, Tang Jiajun, Niu Yiwen, Liu Yingkai, Lu Yechen, Huang Lifang, Zhou Jingqi, Wu Fangyi, Ma Xian
2021, 37(7): 666-667. doi: 10.3760/cma.j.cn501120-20210224-00067
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According to a document issued by the General Office of National Health Commission, "one person, one diagnosis, and one room" is required in the process of outpatient consultation. However, the patient will need to go to another room for dressing change after the doctor checks the wound if sticking ...

Technique and Mehod·Nursing Column
Design and application method of a rapid cooling device for burns in field battle training
Ju Ting, Zhou Qin, Han Juntao, Hu Dahai
2021, 37(7): 668-669. doi: 10.3760/cma.j.cn501120-20200805-00369
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At present, there is no special rapid cooling device for burn injury site in field battle training environment. To solve this problem, our research team designed a rapid cooling device for burns in field battle training. Based on the principle of rapid cooling of liquid nitrogen, the device monitors...

Review
Research advances on skin tissue regeneration in wound repair
Wei Yating, Wu Jun
2021, 37(7): 670-674. doi: 10.3760/cma.j.cn501120-20200604-00296
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Wound repair is one of the common clinical problems faced by burn, plastic, and reconstructive surgeons. Current wound repair strategies applied in clinical settings can only achieve pathological repair instead of physiological regeneration. To 'perfectly' repair the defective tissue is the long-tim...

Research advances on the regulation of interleukin-17 signal transduction and the implication of interleukin-17 in sepsis
Jia Yanhui, Liu Jiaqi, Wang Yunchuan, Wang Hongtao, Tao Ke, Zheng Zhao, Hu Dahai
2021, 37(7): 675-680. doi: 10.3760/cma.j.cn501120-20200515-00266
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Sepsis remains a leading cause of death in critical patients. Both excessive inflammatory response and long-term immunosuppression can lead to the death of sepsis patients. As a key pro-inflammatory cytokine, interleukin-17 (IL-17) plays an important role in the body's inflammatory response and immu...

Research advances on the development and application of clustered regularly interspaced short palindromic repeats (CRISPR)/CRISPR-associated protein system
Tan Jingjie, Peng Yizhi, Huang Guangtao
2021, 37(7): 681-687. doi: 10.3760/cma.j.cn501120-20200329-00201
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Clustered regularly interspaced short palindromic repeats (CRISPR)/CRISPR-associated (Cas) protein system, as an emerging gene editing system, can be divided into class 1 and class 2 systems according to the number of Cas protein. The CRISPR/Cas9 in class 2 system can cleave target nucleic acid only...

Research advances on the application of pulsed dye laser in the early treatment of post-traumatic scars
Liu Zhennan, Zhou Yuemin
2021, 37(7): 688-691. doi: 10.3760/cma.j.cn501120-20200315-00164
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Recent studies have shown that intervention in the early post-traumatic period can inhibit scar hyperplasia and promote scar maturation. Because of its definite therapeutic efficacy and few adverse reactions, it has become an important auxiliary method to prevent scar formation after trauma. This ar...

Research advances on the formation mechanism and diagnosis of bacteria biofilms in chronic wounds
Liu Jiang, Liu Yi
2021, 37(7): 692-696. doi: 10.3760/cma.j.cn501120-20200327-00198
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Bacterial biofilms infection is one of the major factors causing delayed wound healing. Therefore, early diagnosis of bacterial biofilms is critical for successful cure of chronic wounds. Although many techniques have been developed to diagnose the free pathogens in infectious wounds, there is no te...

Research advances on the effect of early intervention on post-traumatic scar formation
Zhao Qiannan, Zhou Yuemin, Ma Yuanyuan, Han Huahua
2021, 37(7): 697-701. doi: 10.3760/cma.j.cn501120-20200315-00169
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Scars caused by trauma will not only affect the appearance and cause dysfunction, but also affect the quality of psychological life of the patients to varying degrees. With the in-depth understanding of the process of scar formation after trauma and the continuous development of related intervention...