2024 Vol. 40, No. 2

Guideline and Consensus
Expert consensus on the treatment of second-degree burn wounds (2024 edition) Ⅱ: surgical treatment and infection prevention and treatment
2024, 40(2): 101-118. doi: 10.3760/cma.j.cn501225-20240112-00015
Abstract:

Second-degree burns are the most common type of burns in clinical practice and hard to manage. The treatment needs not only to consider the possible different effects of dressing change or surgical treatment itself, but also requires the evaluation of many factors such as burn site, ages of patients...

Expert Forum
Several issues that need attention to improve the diagnosis and treatment level of infectious wounds
Liu Yi
2024, 40(2): 119-124. doi: 10.3760/cma.j.cn501225-20231018-00119
Abstract:
Wound infection is an inflammatory response of the host to pathogenic microorganisms. It is a complex pathological process that may manifest either as a rapid onset acute wound infection, or as a prolonged chronic wound infection. Infectious wounds refer to acute or chronic wounds where infection ha...
Pay attention to the prevention and treatment of deep sternal wound infection after sternotomy
Guan Hao, Chen Yang
2024, 40(2): 125-130. doi: 10.3760/cma.j.cn501225-20231212-00235
Abstract:
Deep sternal wound infection (DSWI) is one of the potential and catastrophic complications after cardiac surgery. Despite the use of smaller incisions, routine application of prophylactic antibiotic and optimized blood glucose management, the incidence rate of DSWI still fluctuates between 1% and 5%...
Original Aticle·Repair of Infected Wounds
Effects of cerium oxide nanoenzyme-gelatin methacrylate anhydride hydrogel in the repair of infected full-thickness skin defect wounds in mice
Gu Ya'nan, Xu Xianghao, Wang Yanping, Li Yutao, Liang Zhen, Yu Zhou, Peng Yizhi, Song Baoqiang
2024, 40(2): 131-140. doi: 10.3760/cma.j.cn501225-20231120-00201
Abstract:
Objective To investigate the effects of cerium oxide nanoenzyme-gelatin methacrylate anhydride (GelMA) hydrogel (hereinafter referred to as composite hydrogel) in the repair of infected full-thickness skin defect wounds in mice. Methods This study was an experimental study. Cerium oxide nanoenzyme...
Analysis of clinical data of necrotizing fasciitis secondary to intestinal fistulas and screening the mortality risk factors
Zhao Chenyuyao, Zhang Yushen, Yang Zhanjie, Wang Mingqing, Xue Wenjun, Huo Ran, Zhao Ran
2024, 40(2): 141-150. doi: 10.3760/cma.j.cn501225-20230923-00088
Abstract:
Objective To analyze the clinical data and to screen the mortality risk factors of necrotizing fasciitis (NF) secondary to intestinal fistulas (NFsIF). Methods This study was a retrospective observational study. The data of all NFsIF cases who met the inclusion criteria and were admitted into Shan...
Perioperative management of wounds associated with secondary sternal osteomyelitis and/or mediastinitis after sternotomy and its clinical effects
Zhang Wanfu, Xu Jing, Zhang Jingqun, Han Fei, Tong Lin, Zhang Hao, Guan Hao
2024, 40(2): 151-158. doi: 10.3760/cma.j.cn501225-20231028-00141
Abstract:
Objective To investigate the perioperative management of wounds associated with secondary sternal osteomyelitis and/or mediastinitis after sternotomy, and to evaluate its clinical effects. Methods This study was a retrospective observational study. From January 2017 to December 2022, 36 patients w...
Original Article
Clinical efficacy of posterior femoral muscle flaps combined with posterior femoral cutaneous nerve nutrient vessel flap and closed lavage in the treatment of stage Ⅳ ischial tuberosity pressure ulcers
Cao Xuexin, Zhang Yonglei, Zhao Shuqing, Zhang Qing, Chi Zhenglin
2024, 40(2): 159-164. doi: 10.3760/cma.j.cn501225-20231017-00115
Abstract:
Objective To explore the clinical efficacy of posterior femoral muscle flaps combined with posterior femoral cutaneous nerve nutrient vessel flap and closed lavage in the treatment of stage Ⅳ ischial tuberosity pressure ulcers. Methods This study was a retrospective observational study. From March...
Effect of accurately localized mini anterolateral thigh perforator flap in repairing medium-sized skin and soft tissue defects in fingers
Zhou Feiya, Zhang Xian, Cai Leyi, Chen Mingming, Tao Zhenyu, Zhu Xuwei, Gao Weiyang
2024, 40(2): 165-171. doi: 10.3760/cma.j.cn501225-20231030-00150
Abstract:
Objective To explore the effect of accurately localized mini anterolateral thigh perforator flap in repairing medium-sized skin and soft tissue defects in fingers. Methods The study was a retrospective observational study. From December 2019 to September 2022, 15 patients with medium-sized skin an...
Clinical effect of anterolateral thigh flow-through chimeric perforator free flap transplantation in the treatment of upper limb complex tissue defects with main artery injury
Liu Fei, Yan Weiqi, Ma Qiang, Liu Yibin, Yang Zhibin
2024, 40(2): 172-179. doi: 10.3760/cma.j.cn501225-20231103-00176
Abstract:
Objective To investigate the clinical effect of anterolateral thigh flow-through chimeric perforator free flap transplantation in the treatment of upper limb complex tissue defects with main artery injury. Methods The study was a retrospective observational study. From May 2019 to January 2022, 11...
Application effect of a dual release system of androgen and its antagonist in the repair of full-thickness burn wounds in mice
Huang Rizhong, Wang Yiwei, Huang Heyan, Jiang Ruihan, Xue Nannan, Yin Shaoping, Zhao Hongyu
2024, 40(2): 180-189. doi: 10.3760/cma.j.cn501225-20230802-00033
Abstract:
Objective To explore the optimal ratio of dihydrotestosterone and hydroxyflutamide (hereinafter referred to as DH), construct a dual release system of androgen and its antagonist, and analyze the application effect of this system in the repair of full-thickness burn wounds in mice. Methods This st...
Review
Research advances on the role of microRNA engineered exosomes in diabetic wounds
Jian Xichao, Deng Chengliang
2024, 40(2): 190-195. doi: 10.3760/cma.j.cn501225-20230721-00011
Abstract:
Diabetic wounds are a common complication in patients with diabetes, which is difficult to treat. Current treatment methods for diabetic wounds include debridement, functional dressing coverage, negative pressure therapy, bone cement filling, and skin grafting, etc. MicroRNA (miRNA) engineered exoso...
Research progress on the role of resveratrol in wound healing
Liu Yu, Yang Liping, Liu Baixue, Zhou Shuai, Li Meng, Jia Qing, Yu Xijun
2024, 40(2): 196-200. doi: 10.3760/cma.j.cn501225-20230802-00034
Abstract:
The difficulty of wound healing in patients is a difficult problem that doctors in all clinical departments may encounter, and there is still no good solution. Resveratrol is a kind of natural active substance, which has anti-inflammatory, antioxidant, antibacterial, and angiogenesis promoting effec...