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Volume 39 Issue 9
Sep.  2023
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Article Navigation >  CHINESE JOURNAL OF BURNS AND WOUNDS  > 2023  >  39(9): 886-890
Su YH,Xia WZ,Huang X,et al.Research advances in the treatment of keloid with glucocorticoids[J].Chin J Burns Wounds,2023,39(9):886-890.DOI: 10.3760/cma.j.cn501225-20230602-00198.
Citation: Su YH,Xia WZ,Huang X,et al.Research advances in the treatment of keloid with glucocorticoids[J].Chin J Burns Wounds,2023,39(9):886-890.DOI: 10.3760/cma.j.cn501225-20230602-00198.
shu

Research advances in the treatment of keloid with glucocorticoids

doi: 10.3760/cma.j.cn501225-20230602-00198

  • Department of Plastic and Reconstructive Surgery, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200011, China

Funds:

General Program of National Natural Science Foundation of China 82272264, 82072177

Shanghai Clinical Research Center of Plastic and Reconstructive Surgery Supported by Science and Technology Commission of Shanghai Municipality 22MC1940300

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    Abstract
  • As a first-line classical drug, glucocorticoids are used in most combination treatment regimens of keloid. However, there are issues such as poor treatment efficacy and recurrence of keloid after keloid was treated with glucocorticoids, which seriously affect the therapeutic effect. In recent years, many studies have explored the factors influencing the efficacy of glucocorticoids in treating keloid and the action mechanism of glucocorticoids from different perspectives. Based on this, this paper reviews the mechanism and the factors influencing the efficacy of glucocorticoids in treating keloid, and explores ways to improve the treatment efficacy of glucocorticoids, aiming to provide thoughts for improving glucocorticoid-related diagnostic and therapeutic strategies.

     

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