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Volume 40 Issue 10
Oct.  2024
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Article Navigation >  CHINESE JOURNAL OF BURNS AND WOUNDS  > 2024  >  40(10): 991-995
Chen XL,Liu Y.Research progresses on the role of programmed cell death in the inflammatory response of chronic refractory wounds[J].Chin J Burns Wounds,2024,40(10):991-995.DOI: 10.3760/cma.j.cn501225-20240123-00029.
Citation: Chen XL,Liu Y.Research progresses on the role of programmed cell death in the inflammatory response of chronic refractory wounds[J].Chin J Burns Wounds,2024,40(10):991-995.DOI: 10.3760/cma.j.cn501225-20240123-00029.
shu

Research progresses on the role of programmed cell death in the inflammatory response of chronic refractory wounds

doi: 10.3760/cma.j.cn501225-20240123-00029

  • Department of Burn, Ruijin Hospital, Shanghai Burn Institute, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China

Funds:

General Program of National Natural Science Foundation of China 82072262, 82072173

Youth Science Fund Program of National Natural Science Foundation of China 82302796

More Information
  • Corresponding author: Liu Yan, Email: rjliuyan@126.com
  • Received Date: 2024-01-23
    Available Online: 2024-10-28
    Abstract
  • Continuous inflammatory response and repeated tissue damage lead to a chronic inflammatory state that is an important pathological feature of chronic refractory wounds, and plays an important pathogenic role in the occurrence and development of chronic refractory wounds. Multiple types of programmed cell death can release damage-associated molecular patterns, and trigger or induce sustained inflammatory responses, leading to dysregulated tissue repair. This review will outline the known role of programmed cell death in the inflammatory response of chronic refractory wounds from the perspective of generating damage-associated molecular patterns, and explore possible research directions on the role and mechanism of programmed cell death in chronic refractory wounds.

     

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