水凝胶敷料对糖尿病足创面的促愈合作用研究进展

陈跃华; 徐俊; 徐兰举; 张琳; 刘祥胜; 王淑芳

doi:10.3760/cma.j.cn501120-20200827-00393

水凝胶敷料对糖尿病足创面的促愈合作用研究进展

doi: 10.3760/cma.j.cn501120-20200827-00393

1.
南开大学生命科学学院生物活性材料教育部重点实验室，天津　　300071
2.
天津医科大学朱宪彝纪念医院糖尿病足科，天津　　300134
3.
南开大学医学院，天津　　300071

基金项目:

国家重点研发计划 2017YFC1103504

国家自然科学基金面上项目 81671842, 31870966

详细信息

通讯作者:
王淑芳，Email：wangshufang@nankai.edu.cn

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出版历程
- 收稿日期: 2020-08-27

Research advances on the promotive healing effect of hydrogel dressing for diabetic foot wound

1.
Key Laboratory of Bioactive Materials for Ministry of Education, College of Life Science, Nankai University, Tianjin 300071, China
2.
Department of Diabetic Podiatry, Chu Hisen-I Memorial Hospital, Tianjin Medical University, Tianjin 300134, China
3.
Medical College of Nankai University, Tianjin 300071, China

Funds:

National Key Research and Development Program of China 2017YFC1103504

General Program of National Natural Science Foundation of China 81671842, 31870966

More Information

Corresponding author: Wang Shufang, Email: wangshufang@ nankai.edu.cn

摘要

摘要: 近年来，糖尿病患者人数逐渐增加，发生糖尿病足患者人数也随之增加。糖尿病足具有较高的致残率和致死率，严重影响患者的生活质量，既缩短预期寿命，又带来沉重的社会负担。糖尿病足目前的治疗方法存在不足，组织工程的理念与方法为糖尿病足的治疗提供了新的思路和手段。本文介绍了糖尿病足的发病机制、导致糖尿病足创面难愈合的因素、用于治疗糖尿病足创面的功能性水凝胶敷料，以及功能性水凝胶敷料用于治疗糖尿病动物皮肤创面的技术方法，并对治疗糖尿病足创面的功能性水凝胶敷料未来发展方向进行了展望。
- 糖尿病足 /
- 组织工程 /
- 水凝胶 /
- 创伤敷料 /
- 创面愈合
Abstract: In recent years, the number of diabetic patients has gradually increased, and the number of patients with diabetic foot has also increased. Diabetic foot has a high rate of disability and death, seriously affects the patients' quality of life, shortens life expectancy, and brings heavy social burden. The current treatment methods for diabetic foot are insufficient. The concepts and methods of tissue engineering provide new thoughts and means for the treatment of diabetic foot. This article introduces the pathogenesis of diabetic foot wounds, the factors leading to non-healing of diabetic foot, the applications of functional hydrogel dressings in the treatment of diabetic foot and their technical methods of functional hydrogel dressings for treating skin wounds in diabetic animals, and the future development direction of functional hydrogel dressing for treating diabetic foot wounds is prospected.
- Diabetic foot /
- Tissue engineering /
- Hydrogel /
- Wound dressing /
- Wound healing
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参考文献(43)

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