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负压伤口疗法治疗不同腹部手术后切口愈合不良的临床效果

王雪欣 相阳 孟尧 马兵 胡晓燕 唐洪泰 贲道锋 肖仕初

赵朋, 杨敏烈, 储国平, 等. 猪膀胱脱细胞基质和猪脱细胞真皮基质对糖尿病小鼠全层皮肤缺损创面愈合的影响[J]. 中华烧伤杂志, 2020, 36(12): 1130-1138. DOI: 10.3760/cma.j.cn501120-20200901-00399
引用本文: 王雪欣, 相阳, 孟尧, 等. 负压伤口疗法治疗不同腹部手术后切口愈合不良的临床效果[J]. 中华烧伤杂志, 2021, 37(11): 1054-1060. DOI: 10.3760/cma.j.cn501120-20210518-00194.
Zhao Peng, Yang Minlie, Chu Guoping, et al. Influence of porcine urinary bladder matrix and porcine acellular dermal matrix on wound healing of full-thickness skin defect in diabetic mice[J]. Chin j Burns, 2020, 36(12): 1130-1138. DOI: 10.3760/cma.j.cn501120-20200901-00399
Citation: Wang XX,Xiang Y,Meng Y,et al.Clinical effects of negative pressure wound therapy in treating the poor healing of incisions after different abdominal operations[J].Chin J Burns,2021,37(11):1054-1060.DOI: 10.3760/cma.j.cn501120-20210518-00194.

负压伤口疗法治疗不同腹部手术后切口愈合不良的临床效果

doi: 10.3760/cma.j.cn501120-20210518-00194
基金项目: 

国家自然科学基金面上项目 81871559

海军军医大学第一附属医院“234学科攀峰计划” 2019YXK045

详细信息
    通讯作者:

    肖仕初,Email:huangzhuoxiao4@hotmail.com

Clinical effects of negative pressure wound therapy in treating the poor healing of incisions after different abdominal operations

Funds: 

General Program of National Natural Science Foundation of China 81871559

The 234 Subject Peak Climbing Plan of the First Affiliated Hospital of Naval Medical University 2019YXK045

More Information
    Corresponding author: Xiao Shichu, Email: huangzhuoxiao4@hotmail.com
  • 摘要:   目的  探讨采用负压伤口疗法(NPWT)治疗不同腹部手术后切口愈合不良的临床效果。  方法  采用回顾性观察性研究。2019年6月—2020年12月,海军军医大学第一附属医院烧创伤中心收治42例腹部手术后切口愈合不良的患者,其中男29例、女13例,年龄23~81岁,腹部切口愈合不良病程3~60 d。患者入院后完善术前检查,清创后采用NPWT治疗,根据切口裂开层次将负压值设置为-10.64~-6.65 kPa。待切口血运良好,进行Ⅱ期切口缝合。统计腹部手术原因、腹部切口裂开层次和愈合不良原因,观察腹部切口最终愈合情况及并发症发生情况。  结果  本组患者出现腹部切口愈合不良的腹部手术原因按构成比排名,前4位是结肠癌(9例,占21.4%)、胆管疾病(8例,占19.0%)、肝癌(5例,占11.9%)和阑尾炎(4例,占9.5%)。腹部切口裂开层次在深筋膜层者25例(59.5%)、浅筋膜层者17例(40.5%)。腹部切口愈合不良原因按构成比排名,前3位是感染(24例,占57.1%)、脂肪液化(11例,占26.2%)、缝线反应(5例,占11.9%)。40例患者经NPWT治疗,切口血运改善,行Ⅱ期缝合,第2~3周拆除缝线,切口愈合良好;另外2例患者在使用NPWT治疗期间分别出现了肠瘘、胆漏,拆除负压装置,经充分引流和常规换药治疗后切口愈合。  结论  NPWT治疗不同腹部疾病手术后切口愈合不良,效果较佳,但临床医师需综合评估患者病情决定NPWT的使用时机和使用方式,避免肠瘘、胆漏等并发症的发生。

     

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  • 1  采用负压伤口疗法(NPWT)治疗例1患者右半结肠癌切除、回结肠断端吻合术后腹部切口愈合不良。1A.NPWT治疗第5天,可见肠液外溢;1B.NPWT治疗第5天,拆除负压装置可见肠液持续外溢;1C.常规换药治疗1周,瘘口位于切口下端,肠液引流量减少;1D.常规换药治疗3周,瘘口缩小,切口新鲜,肉芽组织增生明显;1E.常规换药治疗5周,瘘口闭合,切口部分愈合;1F.常规换药治疗7周,切口愈合良好

    2  采用负压伤口疗法(NPWT)治疗例2患者胆囊切除、胆总管切开取石、胆道T型引流管置入术后腹部切口愈合不良。2A.入院时腹部切口感染、裂开;2B.NPWT治疗切口第2天;2C.使用NPWT治疗第3天,胆汁持续从切口渗出;2D.拆除负压装置,常规换药治疗3周,切口基本愈合

    表1  42例腹部切口愈合不良患者腹部手术的原因

    腹部手术原因分类及具体原因例数构成比(%)
    恶性肿瘤
    结肠癌921.4
    肝癌511.9
    胃癌37.1
    胆囊癌12.4
    胰腺癌12.4
    肾癌12.4
    前列腺癌12.4
    良性疾病
    胆管疾病819.0
    阑尾炎49.5
    消化道穿孔37.1
    结肠造口还纳24.8
    肝脓肿12.4
    脐疝12.4
    其他
    剖宫产24.8
    下载: 导出CSV

    表2  42例腹部切口愈合不良患者腹部切口裂开层次及愈合不良原因

    裂开层次及原因例数构成比(%)
    浅筋膜层1740.5
    脂肪液化1126.2
    切口感染614.3
    深筋膜层2559.5
    缝线反应511.9
    腹腔感染716.7
    切口感染1126.2
    异物排斥12.4
    营养不良12.4
    下载: 导出CSV
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  • 收稿日期:  2021-05-18

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