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摘要: 病理性瘢痕不仅会引起局部躯体不适,更会对患者的心理产生影响。随着研究的深入,目前A型肉毒毒素(BTX-A)已被逐渐应用于瘢痕的临床治疗。本文归纳了BTX-A在瘢痕治疗中早期减张、抑制结缔组织增生、减轻皮肤炎症这3种作用机制,并总结了其在不同类型瘢痕治疗中的临床应用。但目前尚未对BTX-A注射治疗瘢痕的时间、方式及配比制订统一标准,并缺乏长期随访结果,未来需更深入探讨,以明确BTX-A抑制瘢痕的机制,并制订统一的BTX-A注射治疗标准,为瘢痕提供更有效的治疗方案。Abstract: Pathological scars cause both local physical discomforts and mental disorders for patients. With the development of research, botulinum toxin type A (BTX-A) has been gradually used in the clinical treatment of scars. This article summarizes three potential mechanisms of BTX-A, including early tension reduction, inhibition of connective tissue hyperplasia, and alleviation of skin inflammation, as well as the clinical application of BTX-A in treating different types of scars. However, at present there is no uniform standard for the time, method, and proportioning of BTX-A injection for scar treatment, and there is also a lack of long-term follow-up results. Further researches are needed in future to clarify the mechanism of BTX-A in inhibiting scars, establish a uniform protocol of BTX-A injection, and provide a more effective treatment plan for scars.
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Key words:
- Cicatrix /
- Botulinum toxins, type A /
- Local injection treatment
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