留言板

尊敬的读者、作者、审稿人, 关于本刊的投稿、审稿、编辑和出版的任何问题, 您可以本页添加留言。我们将尽快给您答复。谢谢您的支持!

姓名
邮箱
手机号码
标题
留言内容
验证码

部分去表皮局部皮瓣修复结核性胸壁缺损创面的临床效果

李鹏程 贾赤宇 李东杰 陈莉萍 郑梦利 申传安

李鹏程, 贾赤宇, 李东杰, 等. 部分去表皮局部皮瓣修复结核性胸壁缺损创面的临床效果[J]. 中华烧伤杂志, 2021, 37(12): 1110-1115. DOI: 10.3760/cma.j.cn501120-20210929-00337.
引用本文: 李鹏程, 贾赤宇, 李东杰, 等. 部分去表皮局部皮瓣修复结核性胸壁缺损创面的临床效果[J]. 中华烧伤杂志, 2021, 37(12): 1110-1115. DOI: 10.3760/cma.j.cn501120-20210929-00337.
Li PC,Jia CY,Li DJ,et al.Clinical effects of partially de-epithelized local flaps in repairing tubercular chest wall defects[J].Chin J Burns,2021,37(12):1110-1115.DOI: 10.3760/cma.j.cn501120-20210929-00337.
Citation: Li PC,Jia CY,Li DJ,et al.Clinical effects of partially de-epithelized local flaps in repairing tubercular chest wall defects[J].Chin J Burns,2021,37(12):1110-1115.DOI: 10.3760/cma.j.cn501120-20210929-00337.

部分去表皮局部皮瓣修复结核性胸壁缺损创面的临床效果

doi: 10.3760/cma.j.cn501120-20210929-00337
基金项目: 

军队后勤科研计划重大项目 ALB18J001

北京市科技计划 Z151100004015199

详细信息
    通讯作者:

    申传安,Email:shenchuanan@126.com

Clinical effects of partially de-epithelized local flaps in repairing tubercular chest wall defects

Funds: 

Major Program of Military Logistics Research Plan ALB18J001

Beijing Science and Technology Plan Z151100004015199

More Information
    Corresponding author: Shen Chuan'an, Email: shenchuanan@126.com
  • 摘要:   目的  探讨部分去表皮局部皮瓣修复结核性胸壁缺损创面的临床效果。  方法  采用回顾性观察性研究方法。2010年4月——2021年2月解放军总医院第八医学中心烧伤整形科收治12例符合入选标准的患者,其中男9例、女3例,年龄(42±18)岁。清创后结核性胸壁缺损范围为4 cm×3 cm×2 cm~16 cm×8 cm×5 cm,均采用部分去表皮局部皮瓣修复,皮瓣宽度等于缺损区的宽度,皮瓣长度较缺损区长度增加2 cm。其中1例患者局部皮瓣切取面积过大导致供区不能直接缝合,采用自体背部游离中厚皮片移植术修复;其余患者局部皮瓣切取面积均较小,供瓣区直接拉拢缝合。观察并记录手术时长、术中出血情况、术后引流管引流量和留置时长;术后2周皮瓣的存活情况、质地和颜色,受区有无皮下积液和皮肤破溃以及供区愈合情况,包括有无切口裂开、局部感染、血肿发生。术后1个月做胸部X线、CT或核磁共振成像,检查患者胸壁缺损创面及伴发的结核病部位有无新发的局部积液和骨质破坏。随访6个月以上,记录患者胸壁缺损创面的手术切口有无瘢痕增生、红肿、窦道等。  结果  患者手术时长为(104±18)min,术中出血量为(119±53)mL,引流管累计引流量为(134±49)mL,引流管留置时长为(5.3±1.7)d。术后2周,患者移植的局部皮瓣全部存活,皮瓣质地和颜色与周围正常皮肤接近,其中1例患者胸壁缺损区切口有渗液,部分切口裂开,行Ⅱ期手术后创面愈合良好;其余患者胸壁缺损区创面均无切口感染、皮下积液或切口裂开等情况。患者供区切口均愈合,无切口裂开和局部感染以及血肿发生。术后1个月,患者胸部影像学检查未观察到术区存在新的骨质破坏。随访6~96个月,1例患者术后12个月在胸壁缺损创面的手术部位切口出现肿胀、破溃及窦道,行Ⅱ期手术后创面愈合良好;其余患者胸壁缺损创面的手术切口愈合良好,无瘢痕、红肿、窦道等。  结论  胸壁结核导致的胸壁缺损创面采用部分去表皮局部皮瓣修复,具有供区损伤小、皮瓣设计灵活、术后创面愈合良好的优点。

     

  • 参考文献(29)

    [1] KangW, YuJ, DuJ, et al. The epidemiology of extrapulmonary tuberculosis in China: a large-scale multi-center observational study[J]. PLoS One, 2020,15(8):e0237753. DOI: 10.1371/journal.pone.0237753.
    [2] PangY, AnJ, ShuW, et al. Epidemiology of extrapulmonary tuberculosis among inpatients, China, 2008-2017[J]. Emerg Infect Dis, 2019,25(3):457-464. DOI: 10.3201/eid2503.180572.
    [3] NatarajanA, BeenaPM, DevnikarAV, et al. A systemic review on tuberculosis[J]. Indian J Tuberc, 2020,67(3):295-311. DOI: 10.1016/j.ijtb.2020.02.005.
    [4] LiuY, ZhangXX, YuJJ, et al. Tuberculosis relapse is more common than reinfection in Beijing, China[J]. Infect Dis (Lond), 2020,52(12):858-865. DOI: 10.1080/23744235.2020.1794027.
    [5] GlaziouP, FloydK, RaviglioneMC. Global epidemiology of tuberculosis[J]. Semin Respir Crit Care Med, 2018,39(3):271-285. DOI: 10.1055/s-0038-1651492.
    [6] MajeedFA, AliA, ZafarU, et al. Outcome analysis of primary chest wall tuberculosis: a series of 32 cases[J]. J Ayub Med Coll Abbottabad, 2021,33(3):357-362.
    [7] NaranjeP, BhallaAS, SherwaniP. Chest tuberculosis in children[J]. Indian J Pediatr, 2019,86(5):448-458. DOI: 10.1007/s12098-018-02847-7.
    [8] HossainM, AzzadAK, IslamS, et al. Multiple chest wall tuberculous abscesses[J]. J Pak Med Assoc, 2010,60(7):589-591.
    [9] KabilanK, GulatiM, BandayIA, et al. Myriad faces of active tuberculosis: intrapulmonary bronchial artery pseudoaneurysm[J]. Vasc Endovascular Surg, 2021:15385744211051812. DOI: 10.1177/15385744211051812.
    [10] Moyano-BuenoD, BlancoJF, López-BernusA, et al. Cold abscess of the chest wall: a diagnostic challenge[J]. Int J Infect Dis, 2019,85:108-110. DOI: 10.1016/j.ijid.2019.05.031.
    [11] IgaN, FuchimotoY, KoyanagiT, et al. A rare case of chest wall tuberculosis: tuberculous scapulothoracic bursitis[J]. Respir Med Case Rep, 2021,34:101537. DOI: 10.1016/j.rmcr.2021.101537.
    [12] DidaceMM, IdaLL, IrèneO, et al. Management of tuberculous cutaneous fistula[J]. Case Rep Surg, 2020,2020:7840963. DOI: 10.1155/2020/7840963.
    [13] KunciwSE, de la CruzEC. Incidental finding of tuberculosis during evaluation for delayed wound healing[J]. Mil Med, 2021,186(3/4):e457-e460. DOI: 10.1093/milmed/usaa366.
    [14] KabiriEH, AlassaneEA, KamdemMK, et al. Tuberculous cold abscess of the chest wall: a clinical and surgical experience. Report of 16 cases(case series)[J]. Ann Med Surg (Lond),2020,51:54-58. DOI: 10.1016/j.amsu.2020.02.001.
    [15] HusseinM, AbdelhadiA, ElarabiA, et al. Extrapulmonary Tuberculosis masquerading as chest wall malignancy: just never ceases to surprise![J]. IDCases, 2021,24:e01114. DOI: 10.1016/j.idcr.2021.e01114.
    [16] 贾赤宇.结核性创面贾赤宇2017观点[M].北京:科学技术文献出版社,2017:12-15.
    [17] MalathiL, DasS, NairJ, et al. Chest wall reconstruction: success of a team approach-a 12-year experience from a tertiary care institution[J]. Indian J Thorac Cardiovasc Surg, 2020,36(1):44-51. DOI: 10.1007/s12055-019-00841-y.
    [18] ShamjiFM. Sepsis in the postpneumonectomy space: pathogenesis, recognition, and management[J]. Thorac Surg Clin, 2021,31(4):407-416. DOI: 10.1016/j.thorsurg.2021.08.001.
    [19] KimWJ, KimWS, KimHK, et al. Reconstruction of small chest wall defects caused by tubercular abscesses using two different flaps[J]. Ann Thorac Surg, 2018,106(5):e249-e251. DOI: 10.1016/j.athoracsur.2018.04.019.
    [20] ChoKD, ChoDG, JoMS, et al. Current surgical therapy for patients with tuberculous abscess of the chest wall[J]. Ann Thorac Surg, 2006,81(4):1220-1226. DOI: 10.1016/j.athoracsur.2005.10.044.
    [21] 李鹏程, 郑梦利, 邱亚斌, 等. 皮瓣联合真皮瓣填充修复胸壁结核性溃疡创面八例[J].中华烧伤杂志,2012,28(1):55-56. DOI: 10.3760/cma.j.issn.1009-2587.2012.01.014.
    [22] SotgiuG, CentisR, MiglioriGB. Post-tuberculosis sequelae and their socioeconomic consequences: worth investigating[J]. Lancet Glob Health, 2021,9(12):e1628-e1629. DOI: 10.1016/S2214-109X(21)00454-X.
    [23] AllwoodBW, van der ZalmMM, AmaralA, et al. Post-tuberculosis lung health: perspectives from the First International Symposium[J]. Int J Tuberc Lung Dis, 2020,24(8):820-828. DOI: 10.5588/ijtld.20.0067.
    [24] BehrMA, KaufmannE, DuffinJ, et al. Latent tuberculosis: two centuries of confusion[J]. Am J Respir Crit Care Med, 2021,204(2):142-148. DOI: 10.1164/rccm.202011-4239PP.
    [25] BarryCE, Mayer-BarberKD. Signature required: the transcriptional response to tuberculosis[J].J Exp Med, 2021,218(12):e20211665.DOI: 10.1084/jem.20211665.
    [26] SakurabaM, SagaraY, KomatsuH. Surgical treatment of tuberculous abscess in the chest wall[J]. Ann Thorac Surg, 2005,79(3):964-967. DOI: 10.1016/j.athoracsur.2004.09.004.
    [27] 江红,臧国庆.肺外结核[J].中华全科医学,2012, 10(1):103-104.
    [28] RayS, TalukdarA, KunduS, et al. Diagnosis and management of miliary tuberculosis: current state and future perspectives[J]. Ther Clin Risk Manag, 2013,9:9-26. DOI: 10.2147/TCRM.S29179.
    [29] GroverSB, JainM, DumeerS, et al. Chest wall tuberculosis--a clinical and imaging experience[J]. Indian J Radiol Imaging, 2011,21(1):28-33. DOI: 10.4103/0971-3026.76051.
  • 1  部分去表皮局部皮瓣修复结核性胸壁缺损的设计示意图。1A.ABCD围成区域为创面区,AEF围成区域为设计的局部皮瓣,BD=DF,AE稍长于AC;1B.皮瓣局部去表皮范围为AGE,GE的长度=创面的深度;1C.局部皮瓣AEF掀起后向上旋转修复创面,去表皮后的真皮脂肪筋膜组织AGE翻转填充到创面ABCD的深部,AG的皮肤边缘与ABC的皮肤相对缝合,G点与C点缝合,D点与F点缝合

    2  采用部分去表皮局部皮瓣修复例1患者结核性胸壁缺损创面。2A.结核性脓胸清创后可见胸壁形成口小底大的胸壁缺损;2B.CT显示肋骨部分缺失(既往手术切除),并有包裹性积液和肋骨的感染破坏;2C.局部皮瓣切取并去除部分表皮;2D.供瓣区直接缝合,部分去表皮局部皮瓣填充清创后的胸壁缺损;2E.第2次手术后3周,切口愈合良好;2F.第2次手术后3周,胸部CT显示胸壁缺损已经被软组织填充修复

    3  采用部分去表皮局部皮瓣修复例2患者结核性胸壁缺损创面。3A.术前胸壁切口下可见有大量坏死组织;3B.设计的2个局部皮瓣部分去表皮后放置到胸壁缺损区待固定;3C.术后1年随访,可见创面愈合良好,无瘢痕增生、红肿、积液

    表1  12例结核性胸壁缺损患者行部分去表皮局部皮瓣修复术的相关情况

    患者编号出血量(mL)手术时间(min)累计引流量(mL)引流管留置时长(d)随访时间(个月)不良事件
    病例18010095454
    病例210580155631
    病例395110187735远期窦道
    病例4112120166822
    病例59075120530
    病例689120150718
    病例715590246620切口裂开
    病例812510090430
    病例950120113592
    病例10858072312
    病例11205130115596
    病例122401209546
    下载: 导出CSV
  • 加载中
图(3) / 表(1)
计量
  • 文章访问数:  339
  • HTML全文浏览量:  96
  • PDF下载量:  50
  • 被引次数: 0
出版历程
  • 收稿日期:  2021-09-29

目录

    /

    返回文章
    返回