2020版日本《结缔组织疾病与血管炎相关皮肤溃疡管理指南》解读

贾汝福; 曹明聪

doi:10.3760/cma.j.cn501225-20220320-00073

2020版日本《结缔组织疾病与血管炎相关皮肤溃疡管理指南》解读

doi: 10.3760/cma.j.cn501225-20220320-00073

贾汝福¹,
曹明聪^2, ,

1.
沧州市中心医院脑科院区院长办公室，沧州　　061001
2.
沧州市中心医院血液净化室,沧州　　061001

详细信息

通讯作者:
曹明聪，Email：1198138073@qq.com

计量
- 文章访问数: 209
- HTML全文浏览量: 85
- PDF下载量: 40
- 被引次数: 0
出版历程
- 收稿日期: 2022-03-20

Interpretation of 2020 edition of Japanese "Guidelines for the management of connective tissue disease/vasculitis-associated skin ulcers"

Jia Rufu¹,
Cao Mingcong^{2
, ,}

1.
The Dean's Office of Brain Department District, Cangzhou Central Hospital, Cangzhou 061001, China
2.
Blood Purification Room, Cangzhou Central Hospital, Cangzhou 061001, China

More Information

Corresponding author: Cao Mingcong, Email: 1198138073@qq.com

摘要

摘要: 结缔组织疾病及血管炎患者常因异常的自身免疫反应导致全身各部位难愈性皮肤溃疡的发生，不同类型疾病引发的皮肤溃疡具有很强的异质性。2020年《The Journal of Dermatology》杂志发表了日本在2016年版本基础上更新的《结缔组织疾病与血管炎相关皮肤溃疡管理指南》，指导临床更加科学规范地进行相关疾病管理。该文通过对该指南进行解读，以期帮助国内临床医师明确结缔组织疾病与血管炎相关皮肤溃疡的诊断与治疗目标，加速皮肤创面愈合，提高愈合质量。
- 结缔组织疾病 /
- 血管炎 /
- 皮肤溃疡 /
- 指南 /
- 解读
Abstract: Patients with connective tissue diseases and vasculitis often develop refractory skin ulcers in various parts of the body due to abnormal autoimmune reactions, and the skin ulcers caused by different types of diseases have strong heterogeneity. In 2020, The Journal of Dermatology published the Japanese "Guidelines for the management of connective tissue disease/vasculitis-associated skin ulcers", which is an updated version of its 2016 edition, to guide clinical management of related diseases in a more scientific and standard way. By interpreting the guidelines, this paper aims to help domestic clinicians clarify the diagnosis and treatment objectives of connective tissue disease and vasculitis-associated skin ulcers, accelerate skin wound healing, and improve healing quality.
- Connective tissue diseases /
- Vasculitis /
- Skin ulcer /
- Guidebooks /
- Interpretation
所有作者均声明不存在利益冲突

HTML全文

参考文献(30)

[1]	谭谦,徐晔.慢性创面治疗的理论和策略[J].中华烧伤杂志,2020,36(9):798-802.DOI: 10.3760/cma.j.cn501120-20200728-00361.
[2]	ShanmugamVK,AngraD,RahimiH,et al.Vasculitic and autoimmune wounds[J].J Vasc Surg Venous Lymphat Disord,2017,5(2):280-292.DOI: 10.1016/j.jvsv.2016.09.006.
[3]	MűzesG,SiposF.[Primary immunodeficiency and autoimmune diseases][J].Orv Hetil,2018,159(23):908-918.DOI: 10.1556/650.2018.31064.
[4]	RayalaBZ.Skin ulcers: prevention and diagnosis of pressure, venous leg, and arterial ulcers[J].FP Essent,2020,499:11-18.
[5]	FujimotoM,AsaiJ,AsanoY,et al.Wound, pressure ulcer and burn guidelines - 4: guidelines for the management of connective tissue disease/vasculitis-associated skin ulcers[J].J Dermatol,2020,47(10):1071-1109.DOI: 10.1111/1346-8138.15186.
[6]	FujimotoM,AsanoY,IshiiT,et al.The wound/burn guidelines-4: guidelines for the management of skin ulcers associated with connective tissue disease/vasculitis[J].J Dermatol,2016,43(7):729-757.DOI: 10.1111/1346-8138.13275.
[7]	朱悦.内皮细胞活化参与类风湿血管炎病理机制研究进展[J].安徽医科大学学报,2020,55(7):1147-1150.DOI: 10.19405/j.cnki.issn1000-1492.2020.07.033.
[8]	高亚丽,宋秀祖,刘泽虎,等.类风湿性嗜中性皮炎一例[J].中华皮肤科杂志,2018,51(7):541.DOI: 10.3760/cma.j.issn.0412-4030.2018.07.020.
[9]	王子园,张帆,周桂芝,等.氨苯砜单疗治疗类风湿性嗜中性皮炎一例[J].中国麻风皮肤病杂志,2022,38(4):238-242.DOI: 10.12144/zgmfskin202204238.
[10]	DentonCP,KhannaD.Systemic sclerosis[J].Lancet,2017,390(10103):1685-1699.DOI: 10.1016/S0140-6736(17)30933-9.
[11]	于伶,屠文震,薛鸾,等.活血化瘀方熏洗对系统性硬化症患者雷诺现象的疗效观察[J].中国中西医结合皮肤性病学杂志,2022,21(1):40-43.DOI: 10.3969/j.issn.1672-0709.2022.01.008.
[12]	于聪,周城,张建中.硬皮病样皮肤移植物抗宿主病24例临床特征分析[J].中华皮肤科杂志,2022,55(2):123-128.DOI: 10.35541/cjd.20210318.
[13]	沈琰琳,任天丽,杜迅.前列地尔治疗自身免疫病引起末梢循环障碍的临床疗效研究[J].中国微循环,2009,13(6):576-577.
[14]	王启华,陈树民,庞新华,等.硬皮病伴发右上肢皮肤坏疽1例[J].中国皮肤性病学杂志,2006,20(6):380.DOI: 10.3969/j.issn.1001-7089.2006.06.031.
[15]	蔡金星.积雪苷的临床应用[J].海峡药学,2007,19(9):92-93.DOI: 10.3969/j.issn.1006-3765.2007.09.056.
[16]	KiriakidouM,ChingCL.Systemic lupus erythematosus[J].Ann Intern Med,2020,172(11):ITC81-ITC96.DOI: 10.7326/AITC202006020.
[17]	XieT,YeJ,RerkasemK,et al.The venous ulcer continues to be a clinical challenge: an update[J/OL].Burns Trauma,2018,6:18[2022-03-20].https://pubmed.ncbi.nlm.nih.gov/29942813/.DOI: 10.1186/s41038-018-0119-y.
[18]	MartinezGP,ZabaletaME,Di GiulioC,et al.The role of chloroquine and hydroxychloroquine in immune regulation and diseases[J].Curr Pharm Des,2020,26(35):4467-4485.DOI: 10.2174/1381612826666200707132920.
[19]	中华医学会皮肤性病学分会红斑狼疮研究中心.皮肤型红斑狼疮诊疗指南(2019版)[J].中华皮肤科杂志,2019,52(3):149-155.DOI: 10.3760/cma.j.issn.0412-4030.2019.03.001.
[20]	SasakiH,KohsakaH.Current diagnosis and treatment of polymyositis and dermatomyositis[J].Mod Rheumatol,2018,28(6):913-921.DOI: 10.1080/14397595.2018.1467257.
[21]	AguilaLA,LopesMR,PrettiFZ,et al.Clinical and laboratory features of overlap syndromes of idiopathic inflammatory myopathies associated with systemic lupus erythematosus, systemic sclerosis, or rheumatoid arthritis[J].Clin Rheumatol,2014,33(8):1093-1098.DOI: 10.1007/s10067-014-2730-z.
[22]	李利根,柴家科.肢体高压电烧伤软组织及血管损伤的影像学判断及临床意义[J].中华烧伤杂志,2020,36(11):1009-1012.DOI: 10.3760/cma.j.cn501120-20190904-00371.
[23]	李登丽,郑海雁,史冬梅.皮肌炎伴钙质沉着一例并国内外105例回顾分析[J].中国麻风皮肤病杂志,2022,38(1):14-20.DOI: 10.12144/zgmfskin202101014.
[24]	梁伟强,温立强,张金明,等.皮肤钙质沉着症及治疗[J].临床皮肤科杂志,2011,40(11):702-704.DOI: 10.3969/j.issn.1000-4963.2011.11.029.
[25]	吕嫔果,陈朝良.复方黄柏液换药治疗皮肌炎皮肤溃烂的疗效观察[J].海峡药学,2013,25(2):100-101.DOI: 10.3969/j.issn.1006-3765.2013.02.050.
[26]	SaadounD,VautierM,CacoubP.Medium- and large-vessel vasculitis[J].Circulation,2021,143(3):267-282.DOI: 10.1161/CIRCULATIONAHA.120.046657.
[27]	GreenwoodJD,MerrySP,BoswellCL.Skin biopsy techniques[J].Prim Care,2022,49(1):1-22.DOI: 10.1016/j.pop.2021.10.001.
[28]	JennetteJC,FalkRJ,BaconPA,et al.2012 revised international Chapel Hill consensus conference nomenclature of vasculitides[J].Arthritis Rheum,2013,65(1):1-11.DOI: 10.1002/art.37715.
[29]	李昌金,顾昊煜,孔瑞娜.利妥昔单抗与环磷酰胺联合硫唑嘌呤治疗抗中性粒细胞胞质抗体相关性血管炎有效性Meta分析[J].中华风湿病学杂志,2022,26(1):14-21.DOI: 10.3760/cma.j.cn141217-20210726-00292.
[30]	WangM,WuP,HuangJ,et al.Skin cell-derived extracellular vesicles: a promising therapeutic strategy for cutaneous injury[J/OL].Burns Trauma,2022,10:tkac037[2022-11-20].https://pubmed.ncbi.nlm.nih.gov/36267497/.DOI: 10.1093/burnst/tkac037.