自身免疫病相关慢性创面的研究和治疗进展

张路; 王星童; 褚万立

doi:10.3760/cma.j.cn501225-20220329-00101

自身免疫病相关慢性创面的研究和治疗进展

doi: 10.3760/cma.j.cn501225-20220329-00101

解放军总医院第四医学中心烧伤整形医学部，北京　100048

基金项目:

国家自然科学基金青年科学基金项目 82102320

详细信息

通讯作者:
褚万立，Email：chuwanli@sina.com

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- 被引次数: 0
出版历程
- 收稿日期: 2022-03-29

Advances on the research and treatment of autoimmune disease-related chronic wounds

Department of Burns and Plastic Surgery, the Fourth Medical Center of PLA General Hospital, Beijing 100048, China

Funds:

Youth Science Foundation Project of National Natural Science Foundation of China 82102320

More Information

Corresponding author: Chu Wanli, Email: chuwanli@sina.com

摘要

摘要: 自身免疫病是由于机体免疫系统被错误导向进而攻击宿主自身所引发的一种疾病。该类疾病患者全身状况差，受血管和皮肤组织病变以及治疗药物等的影响，皮肤一旦破溃极易形成迁延不愈的慢性创面，该类创面治疗难度较大，需要多学科医师联合诊疗。基于此，该文对自身免疫病相关慢性创面的研究和治疗进展进行综述，以期为其临床治疗提供参考。
- 自身免疫疾病 /
- 干细胞 /
- 胞外囊泡 /
- 慢性创面 /
- 微小RNA /
- DNA纳米技术
Abstract: Autoimmune disease is a disease caused by the body's immune system being misdirected to attack the host itself. Patients with this type of diseases are in poor general condition, and are affected by vascular and skin tissue lesions, and therapeutic drugs. Once the skin is broken, chronic wounds that do not heal could easily develop. This type of wounds is difficult to treat and requires joint diagnosis and treatment of multidisciplinary physicians. Therefore, this article reviews the advances on research and treatment of autoimmune disease-related chronic wounds in order to provide reference for their clinical treatment.
- Autoimmune diseases /
- Stem cells /
- Extracellular vesicles /
- Chronic wound /
- microRNA /
- DNA nanotechnology
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