天然生物材料促进创面修复的研究进展

高仪轩; 王凌峰; 巴特; 邹晓防; 曹胜军; 李俊亮; 李芳; 周彪

doi:10.3760/cma.j.cn501225-20220630-00276

天然生物材料促进创面修复的研究进展

doi: 10.3760/cma.j.cn501225-20220630-00276

高仪轩¹,
王凌峰^2, ,,
巴特¹,
邹晓防^3, ,,
曹胜军¹,
李俊亮²,
李芳²,
周彪¹

1.
内蒙古包钢医院烧伤外科，包头　　014010
2.
内蒙古烧伤医学研究所，包头　　014010
3.
空军军医大学空军特色医学中心烧伤整形外科，北京　　100142

基金项目:

国家自然科学基金面上项目 82060348

内蒙古自治区自然科学基金 2020MS08022

内蒙古自治区科技计划 2020GG0214

内蒙古自治区科技创新引导项目 CXYD2020BT03

包头市卫生健康委科技计划 wsjkwkj048

空军特色医学中心面上项目 2021LC020

详细信息

通讯作者:
王凌峰，Email：wlf7413@vip.sina.com

邹晓防，Email：zoubai185@163.com

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- 被引次数: 0
出版历程
- 收稿日期: 2022-06-30

Research advances of natural biomaterials in promoting wound repair

1.
Department of Burns, Inner Mongolia Baotou Steel Hospital, Baotou 014010, China
2.
Burn Medical Institute of Inner Mongolia, Baotou 014010, China
3.
Department of Burns and Plastic Surgery, Air Force Specialty Medical Center, Air Force Medical University, Beijing 100142, China

Funds:

General program of National Natural Science Foundation of China 82060348

Natural Science Foundation of Inner Mongolia Autonomous Region 2020MS08022

Science and Technology Program of Inner Mongolia Autonomous Region 2020GG0214

Science and Technology Innovation Guide Project of Inner Mongolia Autonomous Region CXYD2020BT03

Science and Technology Plan of Baotou Health Commission wsjkwkj048

General Program of Air Force Specialty Medical Center 2021LC020

More Information

Corresponding author: Wang Lingfeng, Email: wlf7413@vip.sina.com; Zou Xiaofang, Email: zoubai185@163.com

摘要

摘要: 急慢性创面严重威胁患者的生命健康和生活质量，因此创面修复是近年来国内外学者研究的热点问题。随着材料学与组织工程的发展，越来越多由天然成分制备的生物材料被用于创面修复的基础研究和临床治疗，此类材料可作为创面组织再生的模板，诱导自体细胞黏附、迁移，促进细胞外基质沉积，具有广阔的临床应用前景。该文对创面修复领域中目前研究热门的天然生物材料的特点及其应用进展作一综述，旨在为新型创面敷料及组织工程皮肤研发提供思路。
- 生物相容性材料 /
- 纤维素 /
- 壳聚糖 /
- 丝素蛋白 /
- 创面修复 /
- 脱细胞真皮基质 /
- 脱细胞羊膜
Abstract: Acute and chronic wounds seriously threaten patients' life health and quality of life, therefore, wound repair has become a hot topic of research for scholars at home and abroad in recent years. With the development of material science and tissue engineering, more and more biomaterials prepared from natural ingredients were used in basic research and clinical treatment of wound repair. Such biomaterials can be used as templates for wound tissue regeneration to induce autologous cell adhesion and migration, and promote the deposition of extracellular matrix, which have broad clinical application prospects. This paper reviews the characteristics and application advance of natural biomaterials which are popular in the field of wound repair, aiming to provide ideas for the research and development of new wound dressing and tissue engineering skin.
- Biocompatible materials /
- Cellulose /
- Chitosan /
- Silk fibroin /
- Wound repair /
- Acellular dermal matrix /
- Acellular amniotic membrane
所有作者均声明不存在利益冲突

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