金属微电池敷料在创面修复中的研究进展

陈锦苗; 陈萌; 任晓川; 陈为超; 王娜; 李纪伟

doi:10.3760/cma.j.cn501225-20220926-00416

金属微电池敷料在创面修复中的研究进展

doi: 10.3760/cma.j.cn501225-20220926-00416

青岛大学纺织服装学院，非织造材料与产业用纺织品创新研究院，青岛　　266071

基金项目:

国家自然科学基金青年科学基金项目 52203060

山东省高等学校青创科技支持计划创新团队 2022KJ152

中国博士后科学基金面上项目 2022M711735

青岛市市南区科技计划项目 2022-3-009-SW

详细信息

通讯作者:
李纪伟，Email：jiweili@qdu.edu.cn

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出版历程
- 收稿日期: 2022-09-26
- 网络出版日期: 2023-06-25

Research progress of metal micro-battery dressings in wound repair

College of TextileClothing, Qingdao University, Institute of Nonwovens and Industrial Textile Innovation, Qingdao 266071, China

Funds:

Youth Science Foundation Program of National Natural Science Foundation of China 52203060

Innovation Team of Shandong Province Higher Education Institution Youth Innovation Science and Technology Support Program 2022KJ152

The fellowship of China Postdoctoral Science Foundation 2022M711735

Qingdao City South District Science and Technology Plan Project 2022-3-009-SW

More Information

Corresponding author: Li Jiwei, Email: jiweili@qdu.edu.cn

摘要

摘要: 开发既能抑制细菌感染又能主动促愈合的敷料，对修复创面以及医疗技术的发展具有十分重要的意义。电刺激在创面愈合过程中具有止血、抗菌、抗炎、引导细胞迁移、促再上皮化以及促细胞增殖等多重作用。金属微电池可在无须外接电源的情况下，提供稳定的电刺激能量来源。因此金属微电池与医用敷料的一体化集成，为电刺激在创面修复领域的无线应用带来了新的机遇。该文在介绍电刺激对创面愈合作用机制的基础上，从制备、抗菌、促愈合等角度综述了金属微电池敷料在创面修复中的研究进展，并详细介绍了当前不同类型金属微电池敷料的发展现状、面临的挑战以及未来的发展趋势。
- 生物敷料 /
- 电刺激疗法 /
- 伤口愈合 /
- 金属微电池
Abstract: To develop the dressings that can both inhibit bacterial infection and actively promote healing is of great importance for wound repair and the development of medical technology. Electrical stimulation has multiple roles in wound healing, including hemostasis, antibacterial, anti-inflammatory, guidance of cell migration, promotion of re-epithelialization, and proliferation of cells. Metal micro-battery can provide a stable source of electrical stimulation energy without an external power source. Thus, the integration of metal micro-battery with medical dressings opens up new opportunities for the wireless application of electrical stimulation in wound repair. In this review, the mechanism of the effect of electrical stimulation on wound healing is systematically presented, then recent advances in metal micro-battery dressings, including preparation methods, antibacterial performance, and healing properties are mainly introduced, and the current challenges and prospects of metal micro-battery dressings are also provided.
- Biological dressings /
- Electric stimulation therapy /
- Wound healing /
- Metal micro-battery
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