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2016 Vol. 32, No. 10

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Expert Forum
Treatment of patients with refractory wounds
Lu Shuliang
2016, 32(10): 577-579. doi: 10.3760/cma.j.issn.1009-2587.2016.10.001
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Experienced over twenty years of theoretical accumulation and ten years of clinical exploration, wound repair speciality in our country is in the phase of enhancing comprehensive ability. Our wound healing experts team has successfully carried out treatment of suspected bacterial weapon related chro...
2016, 32(10): 579-579. doi: 10.3760/cma.j.issn.1009-2587.2016.10.101
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2016, 32(10): 581-581. doi: 10.3760/cma.j.issn.1009-2587.2016.10.102
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2016, 32(10): 605-605. doi: 10.3760/cma.j.issn.1009-2587.2016.10.103
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2016, 32(10): 612-612. doi: 10.3760/cma.j.issn.1009-2587.2016.10.104
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2016, 32(10): 618-619. doi: 10.3760/cma.j.issn.1009-2587.2016.10.009
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2016, 32(10): 620-622. doi: 10.3760/cma.j.issn.1009-2587.2016.10.010
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2016, 32(10): 623-625. doi: 10.3760/cma.j.issn.1009-2587.2016.10.011
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2016, 32(10): 626-627. doi: 10.3760/cma.j.issn.1009-2587.2016.10.012
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Expert Comment
Wound healing is still a game of " blind men and an elephant"
Han Chunmao
2016, 32(10): 580-581. doi: 10.3760/cma.j.issn.1009-2587.2016.10.002
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The wound healing includes non-healing and overhealing of the wounds. The results of wound healing are well known by people such as non-healing of the diabetic ulcer or hypertrophic scar after deep burn. In this issue, three papers involve in wound healing, one about autologous adipose-derived mesen...
Basic Research of Wound Repair
Effects of local transplantation of autologous adipose-derived mesenchymal stem cells on the formation of hyperplastic scar on rabbit ears
Chen Lu, Wang Dali, Wei Zairong, Wang Bo, Qi Jianping, Sun Guangfeng
2016, 32(10): 582-587. doi: 10.3760/cma.j.issn.1009-2587.2016.10.003
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Objective To investigate the effects of local transplantation of autologous adipose-derived mesenchymal stem cells (ADSCs) on the formation of hyperplastic scar on rabbit ears. Methods ADSCs were isolated from inguinal fat of six New Zealand rabbits and then sub-cultured. ADSCs of the third passage ...
Expressions of the key proteins of the protein kinase B/mammalian target of rapamycin signaling pathway in skin tissue and wound tissue of diabetic rats
Huang Hong, Qiu Wei, Zhu Ming, Zhang Ya, Cui Wenhui, Xing Wei, Li Xiangyun, An Tianchen, Chen Minjia, Guo Wei, Xu Xiang
2016, 32(10): 588-593. doi: 10.3760/cma.j.issn.1009-2587.2016.10.004
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Objective To explore the changes in the expressions of key proteins of the protein kinase B/mammalian target of rapamycin (Akt/mTOR) signaling pathway in skin tissue and wound tissue of diabetic rats, and to elucidate the associated mechanisms. Methods Seventy-eight SD rats aged from 7 to 8 weeks we...
Effects of severe hypoxia and low concentration of serum protein on the function of human hypertrophic scar fibroblasts
Dong Jiaoyun, Song Fei, Liu Yingkai, Wang Xiqiao
2016, 32(10): 594-598. doi: 10.3760/cma.j.issn.1009-2587.2016.10.005
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Objective To simulate the environmental factors during the process of formation and evolution of hypertrophic scar, so as to explore the effects of moderate and severe hypoxia and low concentration of serum protein on the function of human hypertrophic scar fibroblasts (HSFs). Methods Human HSFs wer...
Original Article
Multicenter epidemiological investigation of hospitalized children with severe burn
Tang Yong, Wang Liangxi, Chen Junjie, Liu Jiaqi, Ren licheng, Liu Xusheng, Yin Meifang, Zhang Dongxia, Huang Yuesheng, Zhang Jiaping
2016, 32(10): 599-605. doi: 10.3760/cma.j.issn.1009-2587.2016.10.006
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Objective To analyze the epidemiological characteristics of hospitalized children with severe burn from several regions in China during 3 years, so as to provide evidence for prevention of burns in children. Methods Relying on the entry system of epidemiology data and biological sample of severe bur...
Acute toxicity and bio-distribution of silver nitrate and nano-silver with different particle diameters in rats
Li Tingzhu, Gong Fan, Zhang Bangyong, Sun Jindu, Zhang Ting, Kong Lu, Xue Yuying, Tang Meng
2016, 32(10): 606-612. doi: 10.3760/cma.j.issn.1009-2587.2016.10.007
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Objective To explore the acute toxic effect and the cumulative target organ of silver nitrate and nano-silver with two different particle diameters in rats. Methods Thirty-six adult SD rats were divided into small particle size nano-silver group (SNS), large particle size nano-silver group (LNS), si...
Effects of microporous polysaccharide on foreign body reaction induced by subcutaneously imbedding expanded polytetrafluoroethylene in mice
Liu Yuanhang, Chen Lei, Wu Yiping, Cao Wei
2016, 32(10): 613-617. doi: 10.3760/cma.j.issn.1009-2587.2016.10.008
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Objective To observe the effects of early applying of microporous polysaccharide on foreign body reaction induced by subcutaneously imbedding expanded polytetrafluoroethylene (e-PTFE) in mice. Methods Ten wide type adult C57BL/6J mice were collected and made a full-thickness skin incision on both si...
Review
Advances in the research of nutrition therapy in patients with severe burn
Chen Qiaohua, Yang Xuekang, Hu Dahai
2016, 32(10): 628-631. doi: 10.3760/cma.j.issn.1009-2587.2016.10.013
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Patients with severe burn are characterized by strong oxidative stress and intense inflammatory response, which will cause metabolic disorder. Therefore, nutrition therapy is very important for severe burn. Nutrition therapy includes enteral nutrition (EN) and parenteral nutrition, and EN has the un...
Antimicrobial applications and toxicity of nano-silver in the medical field
Wang Junjun, Xue Yuying, Tang Meng
2016, 32(10): 631-634. doi: 10.3760/cma.j.issn.1009-2587.2016.10.014
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With the rapid development of modern science and technology, the application of nanomaterial is ubiquitous in our daily life and medical field, in which the application related to nano-silver is more extensive. On one hand, it can make positive effects, such as anti-bacteria, anti-virus, anti-fungi,...
Advances in the research of promotion effect of Aloe vera on wound healing and its clinical use
Song Xinfu, Chen Xiaodong
2016, 32(10): 634-637. doi: 10.3760/cma.j.issn.1009-2587.2016.10.015
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Aloe vera has been widely investigated and used as folk medicine since ancient time. Biologically active substances in its gel include polysaccharides, glycoprotein, enzymes, anthraquinones or phenolic compounds, vitamins, minerals, and so on, which play important roles in anti-inflammatory response...
Advances in the research of application of collagen in three-dimensional bioprinting
Li Haihang, Luo Pengfei, Sheng Jiajun, Liu Gongcheng, Zhu Shihui
2016, 32(10): 638-640. doi: 10.3760/cma.j.issn.1009-2587.2016.10.016
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As a new industrial technology with characteristics of high precision and accuracy, the application of three-dimensional bioprinting technology is increasingly wide in the field of medical research. Collagen is one of the most common ingredients in tissue, and it has good biological material propert...

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