2016 Vol. 32, No. 9

Expert Forum
Phage therapy for bacterial infection of burn
Peng Yizhi, Huang Guangtao
2016, 32(9): 513-516. doi: 10.3760/cma.j.issn.1009-2587.2016.09.001
Abstract:
With the long-term and widespread use of antibiotics, drug resistance of bacteria has become a major problem in the treatment of burn infection. For treating multidrug resistant bacteria, phage therapy has become the focus of attention. Development of phage therapy to fill the blank of this field in...
Burn Infection
Inventory building of phages against extensively drug-resistant Acinetobacter baumannii isolated from wounds of patients with severe burn and related characteristic analysis
Yang Zichen, Deng Liuyang, Gong Yali, Yin Supeng, Jiang Bei, Huang Guangtao, Peng Yizhi, Hu Fuquan
2016, 32(9): 517-522. doi: 10.3760/cma.j.issn.1009-2587.2016.09.002
Abstract:
Objective To build inventory of phages against extensively drug-resistant Acinetobacter Baumannii isolated from wounds of inpatients of burn ICU and analyze related characteristics. Methods In 2014 and 2015, 131 strains of extensively drug-resistant Acinetobacter Baumannii were isolated from wounds ...
Therapeutic effect of phages on extensively drug-resistant Acinetobacter baumannii-induced sepsis in mice
Deng Liuyang, Yang Zichen, Gong Yali, Huang Guangtao, Yin Supeng, Jiang Bei, Peng Yizhi
2016, 32(9): 523-528. doi: 10.3760/cma.j.issn.1009-2587.2016.09.003
Abstract:
Objective To study the therapeutic effect of phages on extensively drug-resistant Acinetobacter baumannii-induced sepsis in mice. Methods (1) Sixty BALB/c mice were divided into blank control group, sepsis control group, antibiotics treatment group, phage treatment group, and phage control group acc...
Analysis of the pathogenic characteristics of 162 severely burned patients with bloodstream infection
Gong Yali, Yang Zichen, Yin Supeng, Liu Meixi, Zhang Cheng, Luo Xiaoqiang, Peng Yizhi
2016, 32(9): 529-535. doi: 10.3760/cma.j.issn.1009-2587.2016.09.004
Abstract:
Objective To analyze the distribution and drug resistance of pathogen isolated from severely burned patients with bloodstream infection, so as to provide reference for the clinical treatment of these patients. Methods Blood samples of 162 severely burned patients (including 120 patients with extreme...
Advances in the research of LuxR family protein in quorum-sensing system of gram-negative bacteria
Chen Zheng, Xiang Jun
2016, 32(9): 536-538. doi: 10.3760/cma.j.issn.1009-2587.2016.09.005
Abstract:
Quorum sensing (QS) is a cell-density-dependent method for information transmission among bacteria, as well as a mechanism for the bacteria to adapt to environment. LuxR family protein plays a key role in gram-negative bacterial QS system as a kind of transcription regulators and participates in a v...
Advances in the research of treating multi-drug resistant bacterial infections
Peng Yuan, Fu Yuexian
2016, 32(9): 539-541. doi: 10.3760/cma.j.issn.1009-2587.2016.09.006
Abstract:
It is imperative to research the treatment strategy for infections caused by multi-drug resistant (MDR) bacteria, as there are increasing reports showing that more and more patients are decimated by the infections of MDR bacteria and the development of antimicrobial drugs is in downturn. Current res...
2016, 32(9): 528-528. doi: 10.3760/cma.j.issn.1009-2587.2016.09.101
Abstract:
2016, 32(9): 535-535. doi: 10.3760/cma.j.issn.1009-2587.2016.09.102
Abstract:
2016, 32(9): 548-548. doi: 10.3760/cma.j.issn.1009-2587.2016.09.103
Abstract:
2016, 32(9): 559-559. doi: 10.3760/cma.j.issn.1009-2587.2016.09.104
Abstract:
2016, 32(9): 566-568. doi: 10.3760/cma.j.issn.1009-2587.2016.09.011
Abstract:
2016, 32(9): 569-571. doi: 10.3760/cma.j.issn.1009-2587.2016.09.012
Abstract:
Original Article
Phase Ⅳ clinical trial for external use of recombinant human granulocyte-macrophage colony-stimulating factor gel in treating deep partial-thickness burn wounds
Liu Jian, Liao Zhenjiang, Zhang Qin
2016, 32(9): 542-548. doi: 10.3760/cma.j.issn.1009-2587.2016.09.007
Abstract:
Objective To evaluate the clinical efficacy and safety of external use of recombinant human granulocyte-macrophage colony-stimulating factor (rhGM-CSF) gel on deep partial-thickness burn wounds. Methods Sixty-eight hospitals in our country including our unit performed a phase Ⅳ clinical trial for rh...
Efficacy of a hydrosurgery system applied in the debridement of extensive residual wounds of patients with severe burn
Liu Gongcheng, Kan Zhaohui, Sheng Jiajun, Li Haihang, Li Lei, Sun Yu, Ji Shizhao, Zhu Shihui
2016, 32(9): 549-554. doi: 10.3760/cma.j.issn.1009-2587.2016.09.008
Abstract:
Objective To explore the efficacy of a hydrosurgery system applied in the debridement of extensive residual wounds of patients with severe burn prospectively. Methods Seventy-six severely burned patients with extensive residual wounds after treatment were admitted into Department of Burn Surgery of ...
Influence of covering of auto-crosslinked sodium hyaluronate gel in combination with xenogenic acellular dermal matrix on healing of full-thickness skin defect wound in pig
Qiu Yuxuan, Zhang Guoan, Wan Jiangbo, Zhao Xiaozhuo
2016, 32(9): 555-559. doi: 10.3760/cma.j.issn.1009-2587.2016.09.009
Abstract:
Objective To explore the influence of covering of auto-crosslinked sodium hyaluronate gel in combination with xenogenic acellular dermal matrix (ADM) on healing of full-thickness skin defect wound in pig. Methods Totally four 10 cm×10 cm full-thickness skin defect wounds were reproduced symmetricall...
Effect of low-energy 633 nm red light stimulation on proliferation and reactive oxygen species level of human epidermal cell line HaCaT
Chen Zhiyong, Li Dongliang, Duan Xiaodong, Peng Daizhi
2016, 32(9): 560-565. doi: 10.3760/cma.j.issn.1009-2587.2016.09.010
Abstract:
Objective To investigate the changes of proliferative activity and reactive oxygen species level of human epidermal cell line HaCaT after being irradiated with low-energy 633 nm red light. Methods Irradiation distance was determined through preliminary experiment. HaCaT cells were conventionally sub...
Review
Current situation and reflection on the treatment of relative low-heat burns
Lei Wanjun, Jing Aihua
2016, 32(9): 572-574. doi: 10.3760/cma.j.issn.1009-2587.2016.09.013
Abstract:
Relative low-heat burn can cause primary and secondary damage, and its basic research and clinical studies need to be carried out urgently. In this article, we review content related to relative low-heat burn, including pathogenesis, epidemiological characteristics, and prevention and treatment base...
Application of a hydrosurgery system in debridement of various types of burn wounds
Li Mengyun, Mao Yuangui, Guo Guanghua, Liu Dewu
2016, 32(9): 574-576. doi: 10.3760/cma.j.issn.1009-2587.2016.09.014
Abstract:
Burn wound healing is closely associated with the depth of wound and early debridement. The traditional ways of debridement have certain limitations and often result in poor appearance and function of repaired area. At present, the hydrosurgery system has been applied clinically in burn field. This ...