Wound repair has its inherent pathophysiological mechanism, presenting a complex network regulation. However, these contents are not detailed exhaustively or systematically in the medical undergraduate education system in China and even the world. Therefore, it is difficult for those clinicians who ...

Burn patients with large area of skin defect are prone to cause wound infection, severe fluid loss, and hypermetabolism, etc, which lead to sequential dysfunction of multiple systems and easily induce severe systemic infections and sepsis. At present, sepsis has been the leading causes of death in s...

With the rapid development of modern treatment methods for chronic wounds, it plays a positive role in the clinical treatment of this kind such disease. However, the traditional treatment methods for chronic wounds also have potential advantages. We should conduct in-depth research on these methods ...

Objective To investigate the effects of medical maggot excretions/secretions (ES) on neutrophils phagocytosis and bactericidal effect in patients with diabetic foot ulcer (DFU). Methods The experimental research method was used. Thirty DFU patients (16 males and 14 females, aged (64±7) years)who wer...

Objective To observe the effect of interleukin-6 (IL-6) on the phenotype and function of human umbilical vein endothelial cells (HUVECs) and explore the role of IL-6 in the process of endothelial-to-mesenchymal transition (EndMT). Methods The experimental research method was used. Fresh umbilical co...

Objective To investigate the status and influencing factors of skin cleaning outside wound (hereinafter referred to as skin) in adult trauma patients. Methods A multicenter cross-sectional investigation was conducted. From September 1 to 30, 2020, a total of 952 adult trauma patients who met the inc...

Objective To evaluate the clinical effects of 5-fluorouracil in different mass concentrations combined with triamcinolone in the treatment of keloids. Methods From March 2018 to March 2019, 29 patients with 31 keloids receipted in the Department of Plastic Surgery of Fujian Medical University Union ...

Objective To investigate the effects of positive end-expiratory pressure (PEEP) setting of mechanical ventilation guided by esophageal pressure in the treatment of patients with traumatic craniocerebral injury combined with acute respiratory distress syndrome (ARDS). Methods The retrospective cohort...

Objective To explore the clinical effects of anterolateral thigh perforator flap with sensory nerves in repairing the plantar skin and soft tissue defects. Methods From January 2016 to March 2019, 13 male patients with plantar skin and soft tissue defects were admitted to the Department of Foot and ...

Objective To explore the effects and mechanisms of polycaprolactone-cellulose acetate (PCL-CA) nanofiber scaffold loaded with rat epidermal stem cells (ESCs) on wound healing of full-thickness skin defects in rats. Methods The experiment research method was applied. The primary ESCs were isolated fr...

Objective To observe the clinical effect of treatment with follicular unit extraction (FUE) and transplantation in treating cicatricial alopecia. Methods The retrospective cohort study was conducted. From January 2012 to January 2018, 56 patients (36 males and 20 females, aged (25±9) years, 1% to 30...

Objective To analyze and discuss the psychological needs of family members of critically ill burn inpatients in semi-closed wards and their related influence factors. Methods A cross-sectional survey was conducted among the 82 burn patients, who met the inclusion criteria and were admitted to the De...

Objective To explore the influence of parental compliance on the treatment of hypertrophic scars in burn children. Methods A retrospective cohort study method was used. From June 2014 to June 2019, 49 children with post-burn hypertrophic scars who met the inclusion criteria and visited the outpatien...

Hypertrophic scars and keloids are common sequelae after wound healing, with a high incidence, which seriously affect the patient's quality of life. However, there is still a lack of effective prevention and treatment methods, mainly because the pathogenesis of scars is not clear. Current research b...

Skin is an important defense barrier of human body and one of the most vulnerable organs. Wounds are the result of damage to the integrity of skin. Chronic wounds and hypertrophic scar formation are the results of abnormal wound healing, and are also the clinical problems those need to be resolved u...