2021 Vol. 37, No. 9

2021, 37(9): F01-F01. doi: 10.3760/cma.j.issn.1009-2587.2021.09.101
Abstract:
Expert Forum
Metabolic staging and nutritional treatment strategies of severely burned patients
Peng Xi
2021, 37(9): 805-810. doi: 10.3760/cma.j.cn501120-20210802-00264
Abstract:
The complexity of burn metabolism and limitations of its cognition are the core factors leading to dissatisfactory efficacy of nutritional therapy in severe burn patients. Precise understanding of burn metabolic rules is a prerequisite for improving the pertinence and effectiveness of nutritional th...
Original Articles·Burn Metabolism and Nutrition
Study on the effect and mechanism of recombinant human intestinal trefoil factor on intestinal mucosal injury and repair in burned mice
Wu Dan, Wang Chao, Li Teng, Wang Huan, Hu Jianhong, Peng Xi
2021, 37(9): 811-820. doi: 10.3760/cma.j.cn501120-20210412-00125
Abstract:
Objective To establish an efficient human intestinal trefoil factor (ITF) recombinant expression and purification strategy and to observe the effect of recombinant human ITF (rhITF) on intestinal mucosal injury and repair in burned rats and to explore the mechanism. Methods The experimental research...
A prospectively randomized controlled study of the effects of intensive insulin therapy combined with glutamine on nutritional metabolism, inflammatory response, and hemodynamics in severe burn patients
Lou Jiaqi, Li Ye, Cui Qingwei, Zhang Pan, Sun Han, Tang Hao, Zhuang Mengmeng, Sun Yong
2021, 37(9): 821-830. doi: 10.3760/cma.j.cn501120-20210428-00159
Abstract:
Objective To observe the effects of intensive insulin therapy combined with glutamine on nutritional metabolism, inflammatory response, and hemodynamics in severe burn patients. Methods Thirty-two severe burn patients who met the inclusion criteria and hospitalized in the Affiliated Huaihai Hospital...
Analysis of risk factors of early enteral nutrition intolerance in extremely severe burn patients
Pan Yanyan, Xu Sida, Fan Youfen, Tu Jing, Huang Neng, Yu Yaohua, Cui Shengyong, Le Xin, Xu Pei, Jin Guoying, Chen Cui
2021, 37(9): 831-838. doi: 10.3760/cma.j.cn501120-20210511-00180
Abstract:
Objective To explore the risk factors of early enteral nutrition intolerance in extremely severe burn patients. Methods A retrospective case-control study was performed. From January 2018 to December 2020, seventy-six adult patients with extremely severe burns who met the inclusion criteria were adm...
Changes in the related indicators of bone formation and bone resorption in severely burned rats
Gong Xiang, Ye Ziqing, Yu Gang, Zhang Wei, Zhang Weidong, Zhou Xueqing, Li Min, Xie Weiguo
2021, 37(9): 839-845. doi: 10.3760/cma.j.cn501120-20200505-00253
Abstract:
Objective To observe the changes in the related indicators of bone formation and bone resorption in severely burned rats. Methods The experimental research method was adopted. Thirty female Sprague-Dawley rats aged 6 to 8 weeks were divided into sham injury group, 12% total body surface area (TBSA) ...
Original Articles
Establishment and validation of a clinical prediction model for infection risk at the placement sites of skin and soft tissue expanders
Dong Chen, Yu Zhou, Liu Wei, Liu Hengxin, Tang Yinke, Ma Xianjie
2021, 37(9): 846-852. doi: 10.3760/cma.j.cn501120-20200619-00314
Abstract:
Objective To establish a clinical prediction model for infection risk at the placement sites of skin and soft tissue expanders (hereinafter termed as expanders) and to validate the predictive value of the model. Methods A retrospective observational study was conducted. Totally 2 934 patients who un...
Effects and molecular mechanism of histone deacetylase 6 inhibitor Tubastatin A on the prolifera- tion and movement of human skin fibroblasts
Zhang Can, Zhang Qiong, Zhang Junhui, Wang Fan, Zhang Jiaping
2021, 37(9): 853-859. doi: 10.3760/cma.j.cn501120-20200519-00274
Abstract:
Objective To explore the effects and possible molecular mechanism of histone deacetylase 6 (HDAC6) inhibitor Tubastatin A on the proliferation and movement of human skin fibroblasts (HSFs). Methods The experimental research method was used. HSFs in logarithmic growth phase were taken and divided int...
Effects and mechanism of hepatocyte growth factor-modified human adipose mesenchymal stem cells on wound healing of full-thickness skin defects in diabetic rats
Zhang Yue, Han Fei, He Ting, Ji Peng, Zhang Zhi, Tao Ke
2021, 37(9): 860-868. doi: 10.3760/cma.j.cn501120-20200626-00329
Abstract:
Objective To investigate the effects and mechanism of hepatocyte growth factor (HGF)-modified human adipose mesenchymal stem cells (ADSCs) on the wound healing of full-thickness skin defects in diabetic rats. Methods The experimental research method was adopted. The discarded abdominal adipose tissu...
Effects and mechanism of estrogen receptor β agonist on the migration and oxidative stress of human umbilical vein endothelial cell under high glucose condition
Guo Xiaoyu, Zhou Xueqing, Xie Weiguo
2021, 37(9): 869-874. doi: 10.3760/cma.j.cn501120-20200720-00352
Abstract:
Objective To investigate the effects and related mechanism of estrogen receptor β (ERβ) agonist on the migration and oxidative stress of human umbilial vein endothelial cells (HUVECs) under high glucose condition. Methods The experimental research method was adopted. HUVECs were routinely cultured a...
Wound Repair
Clinical effect of perforator flap combined with toe transplantation for repairing thumb damage with soft tissue defect of hand
Yang Tao, Chen Jia, Cheng Beibei, Wang Shuai, Jiang Xiaomeng, Song Li, Zhou Mingwu, Li Shimin
2021, 37(9): 875-879. doi: 10.3760/cma.j.cn501120-20200727-00360
Abstract:
Objective To investigate the clinical effect of perforator flap combined with toe transplantation for repairing thumb damage with soft tissue defect of hand. Methods The retrospective observational study method was used. From May 2014 to June 2019, 8 patients with thumb damage and soft tissue defect...
Review·Burn Metabolism and Nutrition
Research advances on early enteral nutritional therapy in severe burn patients
Luo Yue, Li Ning
2021, 37(9): 880-884. doi: 10.3760/cma.j.cn501120-20210621-00223
Abstract:
Severe burns can lead to persistent hypermetabolism. Studies have shown that early enteral nutrition therapy is related to improving the prognosis of severe burn patients, reducing the mortality rate, and reducing gastrointestinal complications and infectious complications. This article introduces t...
Reviews
Research advances on the application of biocompatible materials in treating diabetic wounds
Liu Kaituo, Hu Dahai
2021, 37(9): 885-886. doi: 10.3760/cma.j.cn501120-20200619-00316
Abstract:
At present, a variety of biocompatible materials have been applied in treating diabetic wounds, and some biocompatible materials have played an important role. Although biocompatible materials have advantages such as decreasing exposure and tension of wounds, and providing microenvironment to stimul...
Research advances on the cholinergic inflammatory reflex and inflammation resolution
Chen Zhuo, He Xiao, Yao Mengwei, Li Zhan, Xu Xiang
2021, 37(9): 885-894. doi: 10.3760/cma.j.cn501120-20200609-00299
Abstract:
The vagus nerve plays an important role in regulating the homeostasis of inflammation. Inflammation signals in the body are passed to the vagus nerve efferent fibers via nerve reflexes, and the signals generated by efferent fibers will play an anti-inflammatory role in various inflammatory diseases ...
Research advances on the effect of resistance training on the rehabilitation of burned children
Yang Sha, Qiu Lin
2021, 37(9): 895-899. doi: 10.3760/cma.j.cn501120-20200717-00349
Abstract:
Children are at a critical period of growth and development, their body function and quality of life will be greatly reduced by the direct or indirect impact of burns. Therefore, rehabilitation therapy after burns is very important for the treatment of burned children. Resistance training is one of ...
Research advances on skin sweat gland regeneration induced by stem cells and tissue engineering
Zeng Yingnan, Kang Yangbo, Xu Yong'an
2021, 37(9): 900-904. doi: 10.3760/cma.j.cn501120-20200624-00328
Abstract:
As the largest organ in mammals, skin is the first protective barrier against external stimuli. Sweat glands are one of the important cutaneous appendages and play an important role in maintaining electrolyte balance and regulating body temperature. Patients with extensive deep burns usually suffer ...