2022 Vol. 38, No. 3

Expert Forum
Rehabilitation strategy for the improvement of long-term outcomes of patients after sepsis
Yao Yongming, Zhang Hui
2022, 38(3): 201-206. doi: 10.3760/cma.j.cn501120-20211004-00344
Abstract:
Survivors of sepsis still face high risks of secondary infection and mortality after hospital discharge. Meanwhile, the persistent cognitive, psychological, and physical disorders affect their long-term outcomes and life qualities. In the current review, we analyze the factors for the poor outcomes ...
Original Articles · Burn Infection
Predictive values of serum 8-hydroxydeoxyguanosine on disease progression and prognosis of patients with sepsis
Chen Xiaorong, Jiang Danwei, Tang Yahui, Xu Chang, Zhi Shaoce, Hong Guangliang, Lu Zhongqiu, Zhao Guangju
2022, 38(3): 207-214. doi: 10.3760/cma.j.cn501120-20210910-00311
Abstract:
Objective To investigate the values of serum 8-hydroxydeoxyguanosine (8-OHdG) in predicting disease progression and prognosis of patients with sepsis. Methods The prospective observational research methods were used. A total of 124 patients with sepsis who met the inclusion criteria were admitted to...
Effects of exosomes from human adipose-derived mesenchymal stem cells on inflammatory response of mouse RAW264.7 cells and wound healing of full-thickness skin defects in mice
Shen Kuo, Wang Xujie, Liu Kaituo, Li Shaohui, Li Jin, Zhang Jinxin, Wang Hongtao, Hu Dahai
2022, 38(3): 215-226. doi: 10.3760/cma.j.cn501120-20201116-00477
Abstract:
Objective To investigate the effects of exosomes from human adipose-derived mesenchymal stem cells (ADSCs) on inflammatory response of mouse RAW264.7 cells and wound healing of full-thickness skin defects in mice. Methods The experimental research methods were adopted. The discarded adipose tissue w...
Investigating the effects of Modified Sijunzi Decoction on the diversity of intestinal microflora of severe scald rabbits based on 16S ribosomal RNA high-throughput sequencing
Luo Jinhua, Zhan Jianhua, Liao Wenqiang, Cheng Xing, Huang Kai
2022, 38(3): 227-235. doi: 10.3760/cma.j.cn501120-20200923-00421
Abstract:
Objective To investigate the effects of Modified Sijunzi Decoction on the diversity of intestinal microflora of in severe scald rabbits based on 16S ribosomal RNA (16S rRNA) high-throughput sequencing. Methods The experimental research method was adopted. Ninety Japanese big-ear rabbits regardless g...
Original Articles
Establishment and application of the tenfold rehydration formula for emergency resuscitation of adult patients after extensive burns
Shen Chuan'an, Liu Xinzhu, Li Dawei, Liu Zhaoxing, Zhang Bohan
2022, 38(3): 236-241. doi: 10.3760/cma.j.cn501120-20211109-00383
Abstract:
Objective To explore the scientificity and feasibility of the tenfold rehydration formula for emergency resuscitation of adult patients after extensive burns. Methods A retrospective observational study was conducted. The total burn area (30%-100% total body surface area (TBSA)) and body weight (45-...
Effect of hypochloric acid on Escherichia coli biofilm and the clinical efficacy of hypochloric acid for wounds with Escherichia coli  infection
Liu Jiang, Wu Baolin, Zhu Wanzhao, Liu Jie, Wang Tong, Geng Maomao, Bai Li, Liu Yi
2022, 38(3): 242-250. doi: 10.3760/cma.j.cn501120-20201112-00471
Abstract:
Objective To investigate the effect of hypochloric acid on Escherichia coli biofilm and the clinical efficacy of hypochloric acid for wounds with Escherichia coli infection. Methods One strain of Escherichia coli with the strongest bacterial biofilm forming ability among the strains isolated from sp...
Clinical effects of in situ perforation of preserved split scar matrix in combination with scalp transplantation and vacuum sealing drainage in the treatment of hypertrophic scar in non-functional sites after burns
Meng Yanbin, Lei Jin, Zhang Hairui, Hao Zhenming, Bai Peiyi, Duan Peng
2022, 38(3): 251-255. doi: 10.3760/cma.j.cn501120-20201201-00510
Abstract:
Objective To investigate the clinical effects of in situ perforation of preserved split scar matrix in combination with scalp transplantation and vacuum sealing drainage in the treatment of hypertrophic scar in non-functional sites after burns. Methods A retrospective observational study was used. F...
Effects and mechanism of hydrogen peroxide pretreatment with low molarity on oxidative stress induced apoptosis of mouse bone marrow mesenchymal stem cells
Zhang Shu, Guo Ling, Mi Junwei, Wen Dalin, Sun Jianhui, Zhang Huacai, Du Juan, Cui Li, Jiang Jianxin, Wang Jianmin, Huang Hong
2022, 38(3): 256-265. doi: 10.3760/cma.j.cn501120-20201215-00529
Abstract:
Objective To investigate the effects and mechanism of hydrogen peroxide (HP) pretreatment with low molarity on oxidative stress induced apoptosis of mouse bone marrow mesenchymal stem cells (BMSCs). Methods The experimental research methods were used. BMSCs were isolated and cultured from two 2-week...
Effects of exosomes from human adipose-derived mesenchymal stem cells on pulmonary vascular endothelial cells injury in septic mice and its mechanism
Cai Weixia, Shen Kuo, Cao Tao, Wang Jing, Zhao Ming, Wang Kejia, Zhang Yue, Han Juntao, Hu Dahai, Tao Ke
2022, 38(3): 266-275. doi: 10.3760/cma.j.cn501120-20211020-00362
Abstract:
Objective To investigate the effects of exosomes from human adipose-derived mesenchymal stem cells (ADSCs) on pulmonary vascular endothelial cells (PMVECs) injury in septic mice and its mechanism. Methods The experimental research method was adopted. The primary ADSCs were isolated and cultured from...
Case Report and Literature Review
Two cases of Vibrio vulnificus primary sepsis
Cheng Dasheng, Ji Shizhao, Wang Guangyi, Zhu Feng, Xiao Shichu, Zhu Shihui
2022, 38(3): 276-280. doi: 10.3760/cma.j.cn501120-20201027-00448
Abstract:
This article analyzed the medical records of two patients with Vibrio vulnificus primary sepsis who were admitted to the First Affiliated Hospital of Naval Medical University and reviewed the latest literature. On November 6, 2019, a 54-year-old male patient was admitted to the hospital. The patient...
Reviews
Research advances on stem cell therapy for diabetic foot wounds
Lin Zhihu, Wang Jun, Liang Zunhong, Pan Yunchuan
2022, 38(3): 281-286. doi: 10.3760/cma.j.cn501120-20210828-00292
Abstract:

Diabetic foot wound repair is a challenging issue in clinical practice. Due to the influence of multiple factors including the damage and regeneration failure of local tissue, the impaired pathways of wound repairing through blood vessels and nerve nutrition, and disorders of a variety of cellular f...

Research advances of music therapy and its application in the field of burn treatment
Zhang Xiuhang, Zhou Xin, Hong Lei, Gao Xinxin, Hou Zheyu, Fan Xing, Xie Chunhui, Liu Xi, Chen Xinxin, Yu Jia'ao
2022, 38(3): 287-291. doi: 10.3760/cma.j.cn501120-20201217-00533
Abstract:
Different from other trauma, the scar and pigmentation formed after healing of burn wound not only hinder beauty but also easily lead to a series of sequential psychological problems, such as depression and anxiety. Music therapy, as a supplementary treatment, is widely used in many fields including...
Research advances of real world study in the field of chronic wound
Chen Lingxi, Jia Chiyu, He Yan
2022, 38(3): 291-295. doi: 10.3760/cma.j.cn501120-20210121-00031
Abstract:
In recent years, as a powerful supplement to the randomized controlled trial (RCT), real world study (RWS) has received more and more attention. However, in the field of chronic wounds, most of the patients have complex condition, and the strict inclusion and exclusion criteria of RCT were lack of p...
Research advances on the application of stem cells in sweat gland regeneration
Zhang Jingjuan, Wang Maoying, Zhao Jie, Jiang Duyin
2022, 38(3): 296-300. doi: 10.3760/cma.j.cn501120-20210123-00033
Abstract:

Sweat gland is one of the important appendage organs of the skin, which plays an important role in thermoregulation and homeostasis maintenance. Sweat glands are damaged and unable to self-repair after burns, resulting in perspiration disorders eventually. However, current clinical strategies cannot...