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Volume 38 Issue 10
Oct.  2022
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Article Navigation >  CHINESE JOURNAL OF BURNS AND WOUNDS  > 2022  >  38(10): 989-993
Liu XX,Liu DW.Research advances on the effects of RNA N6-methyladenosine modification in the relevant pathophysiological processes of wound repair[J].Chin J Burns Wounds,2022,38(10):989-993.DOI: 10.3760/cma.j.cn501120-20210804-00267.
Citation: Liu XX,Liu DW.Research advances on the effects of RNA N6-methyladenosine modification in the relevant pathophysiological processes of wound repair[J].Chin J Burns Wounds,2022,38(10):989-993.DOI: 10.3760/cma.j.cn501120-20210804-00267.
shu

Research advances on the effects of RNA N6-methyladenosine modification in the relevant pathophysiological processes of wound repair

doi: 10.3760/cma.j.cn501120-20210804-00267

  • Medical Center of Burn Plastic and Wound Repair, the First Affiliated Hospital of Nanchang University, Nanchang 330006, China

Funds:

Regional Science Fund Project of National Natural Science Foundation of China 81860340, 82160378

More Information
  • Corresponding author: Liu Dewu, Email: dewuliu@126.com
  • Received Date: 2021-08-04
    Available Online: 2022-10-24
    Abstract
  • N6-methyladenosine (m6A) exists widely in eukaryotes as a post-transcriptional modification. This modification is dynamically and reversibly regulated by methyltransferases and demethylases, and is involved in regulating biological effects through m6A binding proteins. Recent studies have elucidated that m6A is involved in embryonic skin morphogenesis, wound repair, and pathophysiological processes such as inflammatory response, angiogenesis, and fibrosis. This review summarizes the role of m6A and its related proteins in the related pathophysiological processes of wound repair, so as to provide a new theoretical basis for the treatment strategy of wound repair.

     

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