Email Alerts
RSS
Volume 38 Issue 10
Oct.  2022
Turn off MathJax
Article Contents
Article Navigation >  CHINESE JOURNAL OF BURNS AND WOUNDS  > 2022  >  38(10): 978-982
Liu XG,Chen L,Li HH,et al.Research advances on the application of natural and recombinant collagen in wound repair[J].Chin J Burns Wounds,2022,38(10):978-982.DOI: 10.3760/cma.j.cn501120-20211123-00394.
Citation: Liu XG,Chen L,Li HH,et al.Research advances on the application of natural and recombinant collagen in wound repair[J].Chin J Burns Wounds,2022,38(10):978-982.DOI: 10.3760/cma.j.cn501120-20211123-00394.
shu

Research advances on the application of natural and recombinant collagen in wound repair

doi: 10.3760/cma.j.cn501120-20211123-00394
  • 1.

    Department of Burn and Wound Repair, the First Affiliated Hospital of Sun Yat-sen University, Guangzhou 510062, China

  • 2.

    School of Biomedical Engineering, Sichuan University, Chengdu 610065, China

  • 3.

    Sun Yat-sen University-Yixian Group Skin Health Precision Research Joint Laboratory, Yue Keli Skin Regeneration Laboratory, Guangzhou 510275, China

Funds:

Natural Science Foundation of Guangdong Province of China 2020B1515020049

"Three Threes" Engineering Team of the First Affiliated Hospital of Sun Yat-sen University Y70214

More Information
  • Corresponding author: Qi Shaohai, Email: qishh@mail.sysu.edu.cn
  • Received Date: 2021-11-23
    Available Online: 2022-10-24
    Abstract
  • Collagen is a macromolecular protein constituting the extracellular matrix of animal connective tissue, which has been widely used and developed in fields of biomedicine, tissue engineering, food, and cosmetics. Due to its advantages such as abundant sources and good biocompatibility, low immunogenicity, and degradability, collagen can be used as a dressing or tissue engineering scaffold for wound repair. According to the source of materials, collagen can be divided into natural collagen and recombinant collagen. Natural collagen is mainly extracted directly from mammals and fish; recombinant collagen is obtained based on genetic engineering technology, and its sources include recombinant expression systems of microorganisms, animals, and plants. This paper summarizes the sources of collagen, and the roles, advantages, and disadvantages of different sources of collagen in wound repair, the particularity and superiority of collagen combined with three-dimensional printing technology in wound repair, the impact of market norms of China's collagen industry on the field of wound repair, and explains the precautions for the development of collagen-related products, aiming to provide new ideas for selecting a suitable source of collagen for wound repair.

     

    • FullText(HTML)
  • loading
    • References(42)
  • [1]
    AdamiakK,SionkowskaA.Current methods of collagen cross-linking: review[J].Int J Biol Macromol,2020,161:550-560.DOI: 10.1016/j.ijbiomac.2020.06.075.
    [2]
    Miranda-NievesD,ChaikofEL.Collagen and elastin biomaterials for the fabrication of engineered living tissues[J].ACS Biomater Sci Eng,2017,3(5):694-711.DOI: 10.1021/acsbiomaterials.6b00250.
    [3]
    LiuX,ZhengC,LuoX,et al.Recent advances of collagen-based biomaterials: multi-hierarchical structure, modification and biomedical applications[J].Mater Sci Eng C Mater Biol Appl,2019,99:1509-1522.DOI: 10.1016/j.msec.2019.02.070.
    [4]
    张丽丽,李贤玉,穆荣,等.皮肤中基底膜的结构与功能[J].中国美容医学,2016,25(10):113-117.
    [5]
    盛嘉隽重组人胶原纳米纤维支架的制备及其生物相容性检测上海第二军医大学2017

    盛嘉隽. 重组人胶原纳米纤维支架的制备及其生物相容性检测[D].上海:第二军医大学,2017.
    [6]
    厉盈颖,张俊杰,吴志明,等.胶原蛋白的制备,生物学特性及应用[J].食品工业,2021,42(8):192-196.
    [7]
    AvilaRodríguez MI,Rodríguez BarrosoLG,SánchezML.Collagen: a review on its sources and potential cosmetic applications[J].J Cosmet Dermatol,2018,17(1):20-26.DOI: 10.1111/jocd.12450.
    [8]
    TangJ,SaitoT.Biocompatibility of novel type I collagen purified from tilapia fish scale: an in vitro comparative study[J].Biomed Res Int,2015,2015:139476.DOI: 10.1155/2015/139476.
    [9]
    SagiA,WalterP,WalterMH,et al."Dermodress", a new temporary skin substitute: pilot study on donor sites[J].Int J Tissue React,1986,8(2):153-156.
    [10]
    YangJY. Clinical application of collagen sheet, YCWM, as a burn wound dressing[J]. Burns, 1990,16(6):457-461. DOI: 10.1016/0305-4179(90)90077-a.
    [11]
    GaoZR,HaoZQ,LiY,et al.Porcine dermal collagen as a wound dressing for skin donor sites and deep partial skin thickness burns[J].Burns,1992,18(6):492-496.DOI: 10.1016/0305-4179(92)90183-u.
    [12]
    朱堂友,伍津津,胡浪,等.壳多糖-胶原-糖胺聚糖凝胶人工皮肤的初步研究[J].中国修复重建外科杂志,2003,17(2):113-116.
    [13]
    DelgadoLM,ShologuN,FullerK,et al.Acetic acid and pepsin result in high yield, high purity and low macrophage response collagen for biomedical applications[J].Biomed Mater,2017,12(6):065009.DOI: 10.1088/1748-605X/aa838d.
    [14]
    张自强,张以河,安琪,等.去端肽Ⅰ型胶原蛋白的免疫原性研究[J].中国组织工程研究,2019,23(22):3542-3548.DOI: 10.3969/j.issn.2095-4344.1738.
    [15]
    IshikawaH,KoshinoT,TakeuchiR,et al.Effects of collagen gel mixed with hydroxyapatite powder on interface between newly formed bone and grafted achilles tendon in rabbit femoral bone tunnel[J].Biomaterials,2001,22(12):1689-1694.DOI: 10.1016/s0142-9612(00)00331-8.
    [16]
    LouzD,BergmansHE,LoosBP,et al.Reappraisal of biosafety risks posed by PERVs in xenotransplantation[J].Rev Med Virol,2008,18(1):53-65.DOI: 10.1002/rmv.559.
    [17]
    FengX,ZhangX,LiS,et al.Preparation of aminated fish scale collagen and oxidized sodium alginate hybrid hydrogel for enhanced full-thickness wound healing[J].Int J Biol Macromol,2020,164:626-637.DOI: 10.1016/j.ijbiomac.2020.07.058.
    [18]
    WiddowsonJP,PictonAJ,VinceV,et al.In vivo comparison of jellyfish and bovine collagen sponges as prototype medical devices[J].J Biomed Mater Res B Appl Biomater,2018,106(4):1524-1533.DOI: 10.1002/jbm.b.33959.
    [19]
    YangH,WangH,ZhaoY,et al.Effect of heat treatment on the enzymatic stability of grass carp skin collagen and its ability to form fibrils in vitro[J].J Sci Food Agric,2015,95(2):329-336.DOI: 10.1002/jsfa.6724.
    [20]
    LeeJM,SuenS,NgWL,et al.Bioprinting of collagen: considerations, potentials, and applications[J].Macromol Biosci,2021,21(1):e2000280.DOI: 10.1002/mabi.202000280.
    [21]
    CaoJ,WangP,LiuY,et al.Double crosslinked HLC-CCS hydrogel tissue engineering scaffold for skin wound healing[J].Int J Biol Macromol,2020,155:625-635.DOI: 10.1016/j.ijbiomac.2020.03.236.
    [22]
    GhoshN,McKillopTJ,JowittTA,et al.Collagen-like proteins in pathogenic E. coli strains[J].PLoS One,2012,7(6):e37872.DOI: 10.1371/journal.pone.0037872.
    [23]
    SallachRE,ConticelloVP,ChaikofEL.Expression of a recombinant elastin-like protein in pichia pastoris[J].Biotechnol Prog,2009,25(6):1810-1818.DOI: 10.1002/btpr.208.
    [24]
    VuorelaA,MyllyharjuJ,PihlajaniemiT,et al.Coexpression with collagen markedly increases the half-life of the recombinant human prolyl 4-hydroxylase tetramer in the yeast Pichia pastoris[J].Matrix Biol,1999,18(5):519-522.DOI: 10.1016/s0945-053x(99)00040-2.
    [25]
    刘斌巴氏毕赤酵母基因工程菌高密度发酵表达重组人源胶原蛋白南京南京理工大学2012

    刘斌.巴氏毕赤酵母基因工程菌高密度发酵表达重组人源胶原蛋白[D].南京:南京理工大学,2012.
    [26]
    李伟娜,尚子方,段志广,等.毕赤酵母高密度发酵产Ⅲ型类人胶原蛋白及其胃粘膜修复功能[J].生物工程学报,2017,33(4):672-682.DOI: 10.13345/j.cjb.160381.
    [27]
    刘彤,郑兴锋,李海航,等.重组人Ⅲ型胶原蛋白水凝胶对猪全层皮肤缺损创面修复的影响[J/CD].中华损伤与修复杂志:电子版,2019,14(2):97-102.DOI: 10.3877/cma.j.issn.1673-9450.2019.02.004.
    [28]
    刘彤重组人胶原蛋白水凝胶和人工真皮分别作为微粒皮移植覆盖物修复全层皮肤缺损的实验研究上海海军军医大学2019

    刘彤.重组人胶原蛋白水凝胶和人工真皮分别作为微粒皮移植覆盖物修复全层皮肤缺损的实验研究[D].上海:海军军医大学,2019.
    [29]
    BenC,LiuX,ShenT,et al.A recombinant human collagen hydrogel for the treatment of partial-thickness burns: a prospective, self-controlled clinical study[J].Burns,2021,47(3):634-642.DOI: 10.1016/j.burns.2020.01.006.
    [30]
    WoodleyDT,KeeneDR,AthaT,et al.Injection of recombinant human type VII collagen restores collagen function in dystrophic epidermolysis bullosa[J].Nat Med,2004,10(7):693-695.DOI: 10.1038/nm1063.
    [31]
    FichardA,TilletE,DelacouxF,et al.Human recombinant alpha1(V) collagen chain. Homotrimeric assembly and subsequent processing[J].J Biol Chem,1997,272(48):30083-30087.DOI: 10.1074/jbc.272.48.30083.
    [32]
    HouY,GueyLT,WuT,et al.Intravenously administered recombinant human type VII collagen derived from Chinese hamster ovary cells reverses the disease phenotype in recessive dystrophic epidermolysis bullosa mice[J].J Invest Dermatol,2015,135(12):3060-3067.DOI: 10.1038/jid.2015.291.
    [33]
    TomitaM,MunetsunaH,SatoT,et al.Transgenic silkworms produce recombinant human type III procollagen in cocoons[J].Nat Biotechnol,2003,21(1):52-56.DOI: 10.1038/nbt771.
    [34]
    QiQ,YaoL,LiangZ,et al.Production of human type II collagen using an efficient baculovirus-silkworm multigene expression system[J].Mol Genet Genomics,2016,291(6):2189-2198.DOI: 10.1007/s00438-016-1251-7.
    [35]
    MerleC,PerretS,LacourT,et al.Hydroxylated human homotrimeric collagen I in Agrobacterium tumefaciens-mediated transient expression and in transgenic tobacco plant[J].FEBS Lett,2002,515(1/2/3):114-118.DOI: 10.1016/s0014-5793(02)02452-3.
    [36]
    XuX,GanQ,CloughRC,et al.Hydroxylation of recombinant human collagen type I alpha 1 in transgenic maize co-expressed with a recombinant human prolyl 4-hydroxylase[J].BMC Biotechnol,2011,11:69.DOI: 10.1186/1472-6750-11-69.
    [37]
    LiJ,ZhangYP,KirsnerRS.Angiogenesis in wound repair: angiogenic growth factors and the extracellular matrix[J].Microsc Res Tech,2003,60(1):107-114.DOI: 10.1002/jemt.10249.
    [38]
    ShiloS,RothS,AmzelT,et al.Cutaneous wound healing after treatment with plant-derived human recombinant collagen flowable gel[J].Tissue Eng Part A,2013,19(13/14):1519-1526.DOI: 10.1089/ten.TEA.2012.0345.
    [39]
    连伟龙,连芩,焦天,等.皮肤修复生物3D打印的研究进展与挑战[J].光电工程,2021,48(8):4-21.DOI: 10.12086/oee.2021.210105.
    [40]
    LeeV,SinghG,TrasattiJP,et al.Design and fabrication of human skin by three-dimensional bioprinting[J].Tissue Eng Part C Methods,2014,20(6):473-484.DOI: 10.1089/ten.TEC.2013.0335.
    [41]
    MichaelS,SorgH,PeckCT,et al.Tissue engineered skin substitutes created by laser-assisted bioprinting form skin-like structures in the dorsal skin fold chamber in mice[J].PLoS One,2013,8(3):e57741.DOI: 10.1371/journal.pone.0057741.
    [42]
    ChauhanT,PeralesE,XiaoK,et al.The achromatic locus: effect of navigation direction in color space[J].J Vis,2014,14(1):97.DOI: 10.1167/14.1.25.
    • Relative Articles
    • Supplements(0)
    • Cited By
  • 加载中

Catalog

    通讯作者: 陈斌, bchen63@163.com
    • 1. 

      沈阳化工大学材料科学与工程学院 沈阳 110142

    1. 本站搜索
    2. 百度学术搜索
    3. 万方数据库搜索
    4. CNKI搜索
    Get Citation
    PDF
    XML

    Article Metrics

    Article views (580) PDF downloads(79) Cited by()
    Proportional views
    Related

    Copyright © Chinese Journal of Burns京ICP备07035254号-14

    E-mail：shaoshangzazhi@163.com

    Website：https://zhsszz.xml-journal.net/

    Supported by: Beijing Renhe Information Technology Co. Ltd    

    /

    DownLoad:  Full-Size Img  PowerPoint
    Return
    Return