Research advances on the application of silk fibroin biomaterials in wound repair

Ding Zhaozhao; Lyu Qiang

doi:10.3760/cma.j.cn501225-20220602-00212

Volume 38 Issue 10

Oct. 2022

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Article Navigation > CHINESE JOURNAL OF BURNS AND WOUNDS > 2022 > 38(10): 973-977

Ding ZZ,Lyu Q.Research advances on the application of silk fibroin biomaterials in wound repair[J].Chin J Burns Wounds,2022,38(10):973-977.DOI: 10.3760/cma.j.cn501225-20220602-00212.

Citation:

Ding ZZ,Lyu Q.Research advances on the application of silk fibroin biomaterials in wound repair[J].Chin J Burns Wounds,2022,38(10):973-977.DOI: 10.3760/cma.j.cn501225-20220602-00212.

Citation:

Ding ZZ,Lyu Q.Research advances on the application of silk fibroin biomaterials in wound repair[J].Chin J Burns Wounds,2022,38(10):973-977.DOI: 10.3760/cma.j.cn501225-20220602-00212.

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Research advances on the application of silk fibroin biomaterials in wound repair

doi: 10.3760/cma.j.cn501225-20220602-00212

Ding Zhaozhao,
Lyu Qiang^,

National Engineering Laboratory for Modern SilkCollaborative Innovation Center of Suzhou Nano Science and Technology, Soochow University, Suzhou 215123, China

Funds:

National Key Research and Development Program of China 2016YFE0204400

More Information

Corresponding author: Lyu Qiang, Email: lvqiang78@suda.edu.cn
Received Date: 2022-06-02
Available Online: 2022-10-24

Abstract

Abstract

Silk fibroin, a natural fibrin, is a suitable matrix biomaterial for wound repair due to its unique properties such as good biocompatibility, tunable biodegradation and mechanical properties, low host inflammatory response, low cost, ease of fabrication, etc. Silk fibroin can be used alone or in combination with other materials to construct various dressings including scaffolds, hydrogels, films, smart mats, and microneedles, which can meet the needs of different wound repair and regulate the wound repair process. Thus, the application research of silk fibroin in skin tissue engineering has increased dramatically. Compared with other natural materials, silk fibroin promotes tissue regeneration and wound repair by improving cell proliferation, migration, and differentiation behavior at different stages, showing unique advantages in different dimensions. Based on the development of silk fibroin wound repair materials in the recent years, this review focuses on the mechanism and application prospect of silk fibroin and its composite materials in wound repair.
- Silk,
- Skin,
- Biological dressings,
- Tissue engineering,
- Wound repair

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References(38)

References

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Research advances on the application of silk fibroin biomaterials in wound repair

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