Volume 38 Issue 10
Oct.  2022
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Chen JQ,Zhu SH.Research advances on the construction of artificial dermal scaffolds based on biomaterials[J].Chin J Burns Wounds,2022,38(10):968-972.DOI: 10.3760/cma.j.cn501225-20220606-00221.
Citation: Chen JQ,Zhu SH.Research advances on the construction of artificial dermal scaffolds based on biomaterials[J].Chin J Burns Wounds,2022,38(10):968-972.DOI: 10.3760/cma.j.cn501225-20220606-00221.

Research advances on the construction of artificial dermal scaffolds based on biomaterials

doi: 10.3760/cma.j.cn501225-20220606-00221
Funds:

National Key Research and Development Program of China 2019YFA0110603

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  • Corresponding author: Zhu Shihui, Email: doctorzhushihui@163.com
  • Received Date: 2022-06-06
    Available Online: 2022-10-24
  • In the field of wound repair, scarless healing and complete reconstruction of skin function are major challenges in clinical and basic research. At present, a variety of artificial dermal scaffolds have been used in the clinical repair of wounds to overcome the problems such as skin structural disorders caused by tissue defects. The biomaterials used to make artificial dermal scaffolds in skin and tissue engineering research mainly include three categories: natural biomaterials, biosynthetic materials, and organic polymer materials. This review summarizes the biocompatibility, bioactivity, and degradability of biomaterials and their effects on wound healing, and provides an overview of artificial dermal scaffold construction strategies based on biomaterials, wound healing cells, and associated cytokines.

     

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