Mechanism and prevention of organ complications post burn injury

Organ complications are the most direct reasons of death for burn and other critically ill patients. Stress and the damage of skin barrier are the two most important initial pathogenic factors after burn injury, which determine the occurrence and development of organ complications and prognosis of burn patients. Systemic inflammatory response syndrome and sepsis are the main causes to induce organ complications post burn injury. There are many challenges about preventing and treating organ complications for severe burn patients.