Abstract: Objective To analyze the clinical characteristics of treadmill abrasion in children. Methods The medical records of 12 children with treadmill abrasion who were admitted to Tongren Hospital of Wuhan University & Wuhan Third Hospital (hereinafter referred to as the author′s unit) from August 2017 to August 2019 were retrospectively analyzed. The data of gender, age, time of seeing a doctor after injury, injury environment and cause, abrasion site, abrasion area, abrasion depth, and wound treatment method and outcome of children were analyzed. Results (1) The children included 5 males and 7 females, with the age of 2 to 6 years. Three children were treated on the same day after injury, and 9 children were treated 7 to 15 days after injury. (2) All the children were injured at home, and the abrasion was mainly caused by touching the running treadmill when their parents were using it. The contact area was mainly the gap between the rear track axle and the metal plate at the lower edge. (3) All the children had abrasion in the hands. The index finger, middle finger, and ring finger were the main involved fingers. The area of the abrasion was 2 cm×2 cm to 8 cm×5 cm, all of them were deep-partial thickness and above. (4) The children were mainly treated in outpatient department (9 children), and 10 children were conducted with conservative treatment. Eleven children had local scar formation, after anti-scar treatment and functional exercise, they recovered well without obvious dysfunction. Conclusions Hands in those children are the most vulnerable part of treadmill abrasion injury, with the index finger, middle finger, and ring finger being frequently involved. The wound area is generally small, and most of the wounds are deep abrasion injuries.