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影响汗腺发育的信号通路及其参与汗腺样细胞体外重建的研究进展

郎东浩 巴特 曹胜军 李芳 董行 李俊亮 王凌峰

郎东浩, 巴特, 曹胜军, 等. 影响汗腺发育的信号通路及其参与汗腺样细胞体外重建的研究进展[J]. 中华烧伤与创面修复杂志, 2022, 38(2): 195-200. DOI: 10.3760/cma.j.cn501120-20201020-00442.
引用本文: 郎东浩, 巴特, 曹胜军, 等. 影响汗腺发育的信号通路及其参与汗腺样细胞体外重建的研究进展[J]. 中华烧伤与创面修复杂志, 2022, 38(2): 195-200. DOI: 10.3760/cma.j.cn501120-20201020-00442.
Lang DH,Ba T,Cao SJ,et al.Research advances on signaling pathways affecting sweat gland development and their involvement in the reconstitution of sweat adenoid cells in vitro[J].Chin J Burns Wounds,2022,38(2):195-200.DOI: 10.3760/cma.j.cn501120-20201020-00442.
Citation: Lang DH,Ba T,Cao SJ,et al.Research advances on signaling pathways affecting sweat gland development and their involvement in the reconstitution of sweat adenoid cells in vitro[J].Chin J Burns Wounds,2022,38(2):195-200.DOI: 10.3760/cma.j.cn501120-20201020-00442.

影响汗腺发育的信号通路及其参与汗腺样细胞体外重建的研究进展

doi: 10.3760/cma.j.cn501120-20201020-00442
基金项目: 

国家自然科学基金地区科学基金项目 82060348

内蒙古自治区科技计划 2020GG0214

详细信息
    通讯作者:

    王凌峰,Email:wlf7413@vip.sina.com

Research advances on signaling pathways affecting sweat gland development and their involvement in the reconstitution of sweat adenoid cells in vitro

Funds: 

Regional Science Foundation of National Natural Science Foundation of China 82060348

Science and Technology Plan of Inner Mongolia Autonomous Region of China 2020GG0214

More Information
    Corresponding author: Wang Lingfeng, Email: wlf7413@vip.sina.com
  • 摘要: 大面积深度烧伤患者因汗腺毁损导致体温调节功能基本丧失,生活质量受到严重影响。目前对于修复汗腺功能的研究较多,然而人体汗腺发育的机制尚未完全阐明。越来越多的研究表明Wnt/β连环蛋白、外胚叶发育不全/外胚叶发育不全受体/核因子κB、音猬因子、叉头框转录因子等信号通路彼此级联共同影响汗腺发育,并且已有研究报道可以利用级联信号通路实现汗腺样细胞的体外重建。现就影响汗腺发育的信号通路及其参与汗腺样细胞的体外重建情况作一综述。

     

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  • 收稿日期:  2020-10-20

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