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原位保留打孔断层瘢痕基质联合头皮移植与负压封闭引流治疗烧伤后非功能部位增生性瘢痕的临床效果

孟艳斌 雷晋 张海瑞 郝振明 白培懿 段鹏

孟艳斌, 雷晋, 张海瑞, 等. 原位保留打孔断层瘢痕基质联合头皮移植与负压封闭引流治疗烧伤后非功能部位增生性瘢痕的临床效果[J]. 中华烧伤与创面修复杂志, 2022, 38(3): 251-255. DOI: 10.3760/cma.j.cn501120-20201201-00510.
引用本文: 孟艳斌, 雷晋, 张海瑞, 等. 原位保留打孔断层瘢痕基质联合头皮移植与负压封闭引流治疗烧伤后非功能部位增生性瘢痕的临床效果[J]. 中华烧伤与创面修复杂志, 2022, 38(3): 251-255. DOI: 10.3760/cma.j.cn501120-20201201-00510.
Meng YB,Lei J,Zhang HR,et al.Clinical effects of in situ perforation of preserved split scar matrix in combination with scalp transplantation and vacuum sealing drainage in the treatment of hypertrophic scar in non-functional sites after burns[J].Chin J Burns Wounds,2022,38(3):251-255.DOI: 10.3760/cma.j.cn501120-20201201-00510.
Citation: Meng YB,Lei J,Zhang HR,et al.Clinical effects of in situ perforation of preserved split scar matrix in combination with scalp transplantation and vacuum sealing drainage in the treatment of hypertrophic scar in non-functional sites after burns[J].Chin J Burns Wounds,2022,38(3):251-255.DOI: 10.3760/cma.j.cn501120-20201201-00510.

原位保留打孔断层瘢痕基质联合头皮移植与负压封闭引流治疗烧伤后非功能部位增生性瘢痕的临床效果

doi: 10.3760/cma.j.cn501120-20201201-00510
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    通讯作者:

    段鹏,Email:dp630613@163.com

Clinical effects of in situ perforation of preserved split scar matrix in combination with scalp transplantation and vacuum sealing drainage in the treatment of hypertrophic scar in non-functional sites after burns

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    Corresponding author: Duan Peng, Email: dp630613@163.com
  • 摘要:   目的  探讨原位保留打孔断层瘢痕基质后行头皮移植结合负压封闭引流治疗烧伤后非功能部位增生性瘢痕的临床效果。  方法  采用回顾性观察性研究。2017年6月—2019年6月,太钢总医院(山西医科大学第六医院)收治符合入选标准的烧伤后面部以外非功能部位增生性瘢痕患者33例,其中男24例、女9例,年龄8~50岁,均行原位保留打孔断层瘢痕基质(瘢痕削薄面积为90~500 cm2)联合头皮移植术,术后对其受区行负压封闭引流固定。术后7 d,观察受区创面有无血肿及感染,同时观察并计算植皮成活率。术后12个月,观察受区瘢痕平整度及厚度,记录患者痒痛情况。术前及术后3、6、12个月,采用温哥华瘢痕量表对患者瘢痕进行评分。观察术后供皮区愈合时间及头发生长情况。对数据行重复测量方差分析、配对样本t检验和Bonferroni校正。  结果  术后7 d,2例患者受区创面出现局部皮下血肿,经换药后愈合;无感染病例。术后7 d,患者植皮成活率为94.6%~99.0%[(96.8±1.2)%]。术后12个月,瘢痕平整度可、厚度未见明显高于正常皮肤,患者痒痛症状消失或较治疗前明显减轻。术前及术后3、6、12个月,患者瘢痕的温哥华瘢痕量表评分分别为(12.1±2.8)、(8.5±1.5)、(7.6±1.6)、(6.7±1.3)分。与术前相比,术后3、6、12个月瘢痕的温哥华瘢痕量表评分均明显降低(t值分别为4.48、4.06、3.97,P<0.01)。所有患者头部供皮部位均在术后4~7 d愈合良好。术后3~6个月,所有患者头部供皮区头发生长良好,达到无瘢痕愈合。  结论  原位保留打孔断层瘢痕基质联合行头皮移植与负压封闭引流治疗烧伤后面部以外非功能部位增生性瘢痕可改善瘢痕外观及增生程度,且供区可达到无瘢痕愈合。

     

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  • 1  原位保留打孔断层瘢痕基质联合头皮移植与负压封闭引流治疗患者前臂烧伤后增生性瘢痕。1A.术前右前臂瘢痕外观;1B.右前臂瘢痕削薄即刻,原位保留瘢痕基质进行打孔;1C.术后6个月复查,瘢痕较术前变薄,整体外观及瘢痕不适症状改善;1D.术后12个月复查,瘢痕整体外观特别是厚度得到明显改善

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  • 收稿日期:  2020-12-01

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