Many reasons can cause damage to a certain part of body, with the damaged tissue showing some corresponding characteristics. There are many uncertainties in the repair of damaged body parts, making it difficult to achieve the ideal function and appearance. In recent years, the repair of mangled injury has made significant progress, but it still faces many challenges. Based on the clinical practice and the current progress in the assessment and repair of mangled injury, this paper summarizes the causes, clinical features, injury assessment, treatment options, repair measures, and the risks of limb salvage, and then puts forward some personal opinions on the definition of mangled injury and treatment strategy optimization for reference.