Multidrug resistant organisms in burn intensive care unit: strategies and opinions
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摘要:
多重耐药菌感染可显著增加烧伤患者的病死率,烧伤重症监护病房(ICU)中多重耐药菌感染的防治已成为重症烧伤患者临床救治中面临的棘手问题。院内感染的防控是减少或避免烧伤ICU内多重耐药菌传播的重要措施,建议从关注病区内病原菌的特征、评估并降低烧伤患者的易感性以及合理应用抗菌药物3个方面优化多重耐药菌感染治疗方案,以达到最佳治疗效果。另外,耐药菌感染的快速精准诊断以及非抗生素治疗是将来可望有所突破的方向。
Abstract:Infections caused by multidrug-resistant (MDR) organisms can significantly increase the mortality of patients with burn injury. Management and prevention of infections by MDR organisms in burn intensive care unit (ICU) become challenging problems in clinical treatment of severe burn patients. The prevention and control of nosocomial infections are important measures to minimize or avoid the spread of MDR organisms in burn ICU. It is recommended to optimize the therapeutic regimen for infections by MDR organisms and achieve the best therapeutic effect by monitoring the characteristics of organisms in local burn unit, evaluating and reducing the susceptibility of burn patients and using the antibiotics rationally. In addition, rapid and accurate diagnosis and non-antibiotic treatment are expected to be the directions for breakthrough in the future.
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Key words:
- Burns /
- Infection /
- Drug resistant organisms
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