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摘要: 慢性、感染性创面愈合一直是临床及科学研究方面引人关注的问题,其中细菌感染及氧化损伤是阻碍创面愈合的关键因素。碳点作为一种新型材料,由于其独特的物理化学性质及良好的生物安全性而备受关注。近年来,针对碳点抗菌性、抗氧化性、光致发光性的研究越来越广泛,碳点在慢性及感染性创面治疗中有巨大潜力。该文综述了碳点抗菌、抗氧化、监测创面感染状态3个方面的研究进展,并进一步探讨了其具体的作用机制、潜在研究方向及应用前景。Abstract: Chronic and infectious wound healing has always been an issue of concern in clinical and scientific research, in which bacterial infection and oxidative damage are the key factors hindering wound healing. Carbon dots, as a new material, has attracted much attention because of its unique physical and chemical properties and good biological safety. In recent years, the researches on the antibacterial property, antioxidant, and photoluminescence properties of carbon dots are more and more extensive and carbon dots have great potential in the treatment of chronic and infectious wounds. This paper reviews the research progress of carbon dots in three aspects: antibacterial, anti-oxidation and monitoring of wound infection are reviewed, and further discusses its specific mechanism, potential research direction, and application prospect.
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Key words:
- Wound healing /
- Anti-bacterial agents /
- Antioxidants /
- Carbon dots
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