重症烧伤患者的代谢分期及营养治疗策略

彭曦

doi:10.3760/cma.j.cn501120-20210802-00264

重症烧伤患者的代谢分期及营养治疗策略

doi: 10.3760/cma.j.cn501120-20210802-00264

彭曦^,

陆军军医大学（第三军医大学）第一附属医院临床医学研究中心，全军烧伤研究所，　创伤、烧伤与复合伤国家重点实验室，重庆　　400038

基金项目:

国家自然科学基金面上项目 81971838

第三军医大学临床重大项目 2018XLC2006

详细信息

通讯作者:
彭曦，Email：pxlrmm@163.com

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出版历程
- 收稿日期: 2021-08-02

Metabolic staging and nutritional treatment strategies of severely burned patients

Peng Xi^,

Clinical Medical Research Center, Institute of Burn Research, State Key Laboratory of Trauma, Burns and Combined Injury, the First Affiliated Hospital of Army Medical University (the Third Military Medical University), Chongqing 400038, China

Funds:

General Program of National Natural Science Foundation of China 81971838

Major Clinical Research Foundation of the Third Military Medical University 2018XLC2006

More Information

Corresponding author: Peng Xi, Email: pxlrmm@163.com

摘要

摘要: 烧伤代谢的复杂性和对其认识的局限性是导致重症烧伤患者营养疗效不甚理想的核心因素，对烧伤代谢规律的准确把握是提升营养针对性和有效性的前提。以往基于能量消耗的烧伤代谢分期对物质代谢关注不够，因而难以全面描述烧伤代谢的整体变化规律和阶段性特征。本文通过对烧伤代谢组学、生理组学和临床检测数据的有效整合，并结合烧伤临床分期的病理生理特征，将重症烧伤患者的代谢过程分为4期，并针对其代谢特征提出了相应的营养治疗策略与措施，以期为进一步提升烧伤营养疗效提供依据。
- 烧伤 /
- 代谢 /
- 营养治疗 /
- 肠外营养 /
- 肠内营养
Abstract: The complexity of burn metabolism and limitations of its cognition are the core factors leading to dissatisfactory efficacy of nutritional therapy in severe burn patients. Precise understanding of burn metabolic rules is a prerequisite for improving the pertinence and effectiveness of nutritional therapy. The previous division of burn metabolic stages based on energy consumption did not pay enough attention to substance metabolism, so it is difficult to fully comprehend the overall change pattern and stage characteristics of burn metabolism. Through the effective integration of the metabonomics, physiomics, and clinical data, combining the pathophysiological characteristics of burns at different clinical phases, this paper suggested that the metabolism of severe burns should be divided into four stages and proposed the corresponding nutritional strategies and measures according to different metabolic characteristics, in order to provide a basis for further enhancing the nutritional efficacy in burn patients.
- Burns /
- Metabolism /
- Nutrition therapy /
- Parenteral nutrition /
- Enteral nutrition
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参考文献(33)

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