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摘要: 休克是严重烧伤最常见的并发症之一,也是主要致死原因之一,休克防治贯穿严重烧伤救治的全过程。严重烧伤后休克类型主要包括:烧伤后早期因大量血管内液体渗出到体表和组织间隙,而引发的血细胞比容升高型、低血容量性休克,常称为烧伤休克;大范围切开减张、消化道应激性溃疡、大面积切削痂手术等原因导致的失血性休克;各种微生物侵袭导致的感染性休克;输注药物或血液等引起的过敏性休克。从机体有效循环血量减少的原因看,烧伤休克与失血性休克同属低血容量性休克,感染性休克和过敏性休克同属血管扩张性休克。由于上述休克的发生时机、发生机制和临床表现各有特点,防治也应采取针对性策略。Abstract: Shock is one of the most common complications and one of the main causes of death after severe burns. The prevention and treatment of shock runs through the whole process of severe burn treatment. Shocks after severe burns, based on their causes, are mainly classified as follows: hypovolemic shock characterized by elevated hematocrit, also known as burn shock, and caused by serious leakage of intravascular fluid to body surface and interstitial spaces in the early stage of burns; hemorrhagic shock caused by large scale of incision and tension reduction, gastrointestinal stress ulcer, or large area of escharectomy and tangential excision surgery; septic shock caused by various microbial invasion; anaphylactic shock caused by infusion of drugs or blood. From the perspective of the reduction of effective circulating volume, burn shock and hemorrhagic shock are hypovolemic shocks, and septic shock and anaphylactic shock are vasodilatory shocks. As the aforementioned shocks vary in terms of occurrence timing, occurrence mechanism, and clinical manifestations, individualized strategies should be adopted for the prevention and treatment.
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Key words:
- Burns /
- Shock /
- Prevention and treatment
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参考文献
(21) [1] Word Health Organization Burns 2018-03-06 2021-11-30 https://www.who.int/en/news-room/fact-sheets/detail/burns Word Health Organization. Burns[EB/OL]. (2018-03-06) [2021-11-30]. https://www.who.int/en/news-room/fact-sheets/detail/burns.
[2] LeclercT,PotokarT,HughesA,et al.A simplified fluid resuscitation formula for burns in mass casualty scenarios: analysis of the consensus recommendation from the WHO Emergency Medical Teams Technical Working Group on Burns[J].Burns,2021,47(8):1730-1738.DOI: 10.1016/j.burns.2021.02.022. [3] PeetersY,VanderveldenS,WiseR,et al.An overview on fluid resuscitation and resuscitation endpoints in burns: past, present and future. Part 1 - historical background, resuscitation fluid and adjunctive treatment[J].Anaesthesiol Intensive Ther,2015,47 Spec No:s6-14.DOI: 10.5603/AIT.a2015.0063. [4] RaeL,FidlerP,GibranN.The physiologic basis of burn shock and the need for aggressive fluid resuscitation[J].Crit Care Clin,2016,32(4):491-505.DOI: 10.1016/j.ccc.2016.06.001. [5] GillenwaterJ,GarnerW.Acute fluid management of large burns: pathophysiology, monitoring, and resuscitation[J].Clin Plast Surg,2017,44(3):495-503.DOI: 10.1016/j.cps.2017.02.008. [6] KangD,YooKY.Fluid management in perioperative and critically ill patients[J].Acute Crit Care,2019,34(4):235-245.DOI: 10.4266/acc.2019.00717. [7] VivóC,GaleirasR,del CazMD.Initial evaluation and management of the critical burn patient[J].Med Intensiva,2016,40(1):49-59.DOI: 10.1016/j.medin.2015.11.010. [8] 杨宗城. 烧伤治疗学[M]. 北京: 人民卫生出版社,2005. [9] JeschkeMG,van BaarME,ChoudhryMA,et al.Burn injury[J].Nat Rev Dis Primers,2020,6(1):11.DOI: 10.1038/s41572-020-0145-5. [10] ClarkA,NeyraJA,MadniT,et al.Acute kidney injury after burn[J].Burns,2017,43(5):898-908.DOI: 10.1016/j.burns.2017.01.023. [11] SuK,XueFS,XueZJ,et al.Clinical characteristics and risk factors of early acute kidney injury in severely burned patients[J].Burns,2021,47(2):498-499.DOI: 10.1016/j.burns.2020.08.018. [12] WolfSE,RoseJK,DesaiMH,et al.Mortality determinants in massive pediatric burns. An analysis of 103 children with > or = 80% TBSA burns (> or = 70% full-thickness)[J].Ann Surg,1997,225(5):554-565; discussion 565-569.DOI: 10.1097/00000658-199705000-00012. [13] AhujaRB,BhattacharyaS.An analysis of 11,196 burn admissions and evaluation of conservative management techniques[J].Burns,2002,28(6):555-561.DOI: 10.1016/s0305-4179(02)00069-4. [14] CopeO,MooreFD.The redistribution of body water and the fluid therapy of the burned patient[J].Ann Surg,1947,126(6):1010-1045.DOI: 10.1097/00000658-194712000-00013. [15] 申传安. 危重烧伤救治新技术体系[M]. 北京: 人民卫生出版社,2021. [16] ArbuthnotMK,GarciaAV.Early resuscitation and management of severe pediatric burns[J].Semin Pediatr Surg,2019,28(1):73-78.DOI: 10.1053/j.sempedsurg.2019.01.013. [17] VlachouE,GoslingP,MoiemenNS.Microalbuminuria: a marker of endothelial dysfunction in thermal injury[J].Burns,2006,32(8):1009-1016.DOI: 10.1016/j.burns.2006.02.019. [18] Müller DittrichMH,Brunow de CarvalhoW,Lopes LavadoE.Evaluation of the "early" use of albumin in children with extensive burns: a randomized controlled trial[J].Pediatr Crit Care Med,2016,17(6):e280-e286.DOI: 10.1097/PCC.0000000000000728. [19] 孙美贞,杜滨,王成.深度烧伤切削痂手术失血量评估及治疗策略[J].中国输血杂志,2013,26(6):561-562. DOI: 10.13303/j.cjbt.issn.1004-549x.2013.06.024. [20] D'AbbondanzaJA, ShahrokhiS. Burn infection and burn sepsis[J].Surg Infect (Larchmt),2021,22(1):58-64.DOI: 10.1089/sur.2020.102. [21] 罗小强,龚雅利,张成,等.159例烧伤重症监护病房导管相关性血流感染患者病原菌分布及耐药性分析[J].中华烧伤杂志,2020,36(1):24-31.DOI: 10.3760/cma.j.issn.1009-2587.2020.01.010.
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