烧伤后认知障碍及其机制的研究进展

罗月; 梁光萍

doi:10.3760/cma.j.cn501225-20221117-00492

烧伤后认知障碍及其机制的研究进展

doi: 10.3760/cma.j.cn501225-20221117-00492

罗月,
梁光萍^,

陆军军医大学（第三军医大学）第一附属医院全军烧伤研究所，创伤、烧伤与复合伤国家重点实验室，重庆　　400038

详细信息

通讯作者:
梁光萍，Email：guangpinglianggg@163.com

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出版历程
- 收稿日期: 2022-11-17

Research advances on post-burn cognitive disorders and its mechanism

Luo Yue,
Liang Guangping^,

Institute of Burn Research, State Key Laboratory of Trauma, Burns and Combined Injury, the First Affiliated Hospital of Army Medical University (the Third Military Medical University), Chongqing 400038, China

More Information

Corresponding author: Liang Guangping, Email: guangpinglianggg@163.com

摘要

摘要: 烧伤后认知障碍是烧伤患者诊断和治疗中不可忽略的重要问题，其机制可能与炎症反应的激活、血脑屏障破坏、下丘脑-垂体-肾上腺轴失衡、神经细胞改变等相关。针对其机制，采取预防及治疗措施将是未来减少烧伤后认知障碍的最优选择。该文就烧伤患者认知障碍的流行病学情况及风险因素、可能的发病机制、诊断、治疗及预防相关研究进展进行综述，为及时准确地评估、处理及预防烧伤患者认知障碍提供参考。
- 烧伤 /
- 认知障碍 /
- 认知功能 /
- 发病机制
Abstract: Cognitive disorders after burns is an important problem that cannot be ignored in the diagnosis and treatment of burn patients. Its mechanism may be related to the activation of inflammatory response, destruction of the blood-brain barrier, hypothalamic-pituitary-adrenal axis imbalance, nerve cell changes, etc. Mechanism-specific prevention and treatment will be the best choice to reduce post-burn cognitive disorders in the future. This review introduces the research advances in epidemiology, risk factors, possible pathogenesis, diagnosis, treatment, and prevention of cognitive disorders in burn patients, in order to provide a reference for timely and accurate assessment, treatment, and prevention of cognitive disorders in burn patients.
- Burns /
- Cognition disorders /
- Cognitive function /
- Pathogenesis
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