Abstract: In recent years, growth in number of mass burn casualties accompanied by large number of deaths, has increased, such as dust blast occurred in Kunshan in 2014 and explosion of chemicals occurred in Tianjin in 2015. These disasters made us aware that our knowledge of care of mass burn casualties must be renewed, and therapeutic strategies currently practiced in ICU should be adopted. This paper introduces the concept of critical burn and provides reference on how to carry out fluid resuscitation, early enteral nutrition, mechanical ventilation, continuous renal replacement therapy, wound management, as well as infection control, etc.