Abstract: Patients with severe burn are characterized by strong oxidative stress and intense inflammatory response, which will cause metabolic disorder. Therefore, nutrition therapy is very important for severe burn. Nutrition therapy includes enteral nutrition (EN) and parenteral nutrition, and EN has the unique advantages. In recent years, more and more researchers focused on the EN for severe burn injuries, but there were still some confusing problems needing to solve. This article reviews the recent research about nutrition therapy for severe burn, including the route of feeding, energy requirements, and supplements of protein, carbohydrates, and microelements, and so on, so as to clarify some confusing questions about nutrition therapy for severe burn in clinical practice.