Skin graft and flap are common tools for wound repair, but donor site would be damaged when harvesting skin graft or flap. If donor site treatment is ignored, various problems concerning the appearance and function of donor site will appear. Therefore, when choosing skin graft or flap, donor site treatment should be considered as an important factor. We should not only seek for the repair effect of recipient site but ignore adverse effect on donor site. We should comprehensively weigh the pros and cons between donor site and recipient site. And paying the lowest price of donor site to achieve the best repair effect of recipient site should be the essential requirement to choose skin graft or flap. For wound cosmetic repair, how to achieve cosmetic repair of donor site should be considered. In recent years, donor site treatment of skin graft and flap has drawn widespread attention and achieved some progress. But compared with cosmetic repair, there still exists some gap. The objective to publish this special topic is to further lay emphasis on the cosmetic repair of donor site by introducing some domestic studies about cosmetic repair of donor site.