2022 Vol. 38, No. 6

Expert Forum
Emphasis on multidisciplinary collaboration in clinical diagnosis and treatment of autoimmune disease-related ulcers
Yu Jia'ao, Zhao Jingchun
2022, 38(6): 501-505. doi: 10.3760/cma.j.cn501120-20211112-00385
Abstract:
The global prevalence and incidence of autoimmune diseases are increasing year by year, and the autoimmune diseases have become a major threat to public health. In the progression of the diseases, persistent and complex abnormal immune responses often lead to long-term unhealed skin ulcers, which no...
Original Articles · Autoimmune Diseases Related wounds
Analysis of clinical features and treatment of pyoderma gangrenosum
Zhao Jingfeng, Hao Daifeng, Li Tao, Feng Guang
2022, 38(6): 506-511. doi: 10.3760/cma.j.cn501225-20220317-00068
Abstract:
Objective To explore the clinical features and treatment of pyoderma gangrenosum (PG). Methods A retrospective observational study was conducted. From January 2012 to July 2021, 25 patients with PG who met the inclusion criteria were admitted to Beijing Fucheng Hospital, including 16 males and 9 fem...
Effects of comprehensive treatment of infected wounds in patients with iatrogenic Cushing's syndrome
Li Shuntang, Lin Yuan, Ou Binxian, Liu Da'en, Li Dehui, Nong Qingwen, Wu Yajun, Qiu Shumei, Huang Zhenxing
2022, 38(6): 512-519. doi: 10.3760/cma.j.cn501225-20220329-00106
Abstract:
Objective To investigate the characteristics and comprehensive treatment of infected wounds in patients with iatrogenic Cushing's syndrome. Methods A retrospective observational study was conducted. From May 2012 to December 2021, the data of 19 patients with iatrogenic Cushing's syndrome discharged...
Original Article·Innovative Technologies and Concepts
Effects and mechanism of negative pressure microenvironment on the neogenesis of human umbilical vein endothelial cells
Dong Yuchen, Huang Rong, Zhao Congying, Li Xueyong
2022, 38(6): 520-531. doi: 10.3760/cma.j.cn501225-20220119-00009
Abstract:
Objective To investigate the effects and mechanism of negative pressure microenvironment on the neogenesis of human umbilical vein endothelial cells (HUVECs). Methods The experimental research methods were adopted. The third to the fifth passage of HUVECs in the logarithmic growth stage were used fo...
Original Articles
Clinical effects of autologous follicular unit extraction transplantation in the treatment of small area secondary cicatricial alopecia after burns
Dai Jiaojiao, Wang Ling, Qiu Haiyang, Huang Xinyi, Tian Yuxin, Peng Qin, Liu Yang, Guan Hao
2022, 38(6): 532-537. doi: 10.3760/cma.j.cn501120-20210224-00064
Abstract:
Objective To explore the clinical effects of autologous follicular unit extraction (FUE) transplantation in the treatment of small area secondary cicatricial alopecia (hereinafter referred to as cicatricial alopecia) after burns. Methods A retrospective observational study was carried out. According...
A cross-sectional investigation and analysis of early treatment of partial-thickness burn wounds by professional burn medical staff in China
Huang Jie, Li Shuyuan, Wang Xuexin, Li Linhui, Ye Xiaofei, Ji Shizhao
2022, 38(6): 538-548. doi: 10.3760/cma.j.cn501225-20220317-00065
Abstract:
Objective To assess the current situation of early treatment of partial-thickness burn wounds by professional burn medical staff in China, and to further promote the standardized early clinical treatment of partial-thickness burn wounds. Methods A cross-sectional investigation was conducted. From No...
Prevalence and risk factors of deep venous thrombosis of lower extremity in patients with stage and pressure ulcers on admission
Zhang Wei, Huang Hongjun, Zhang Junfeng, Liu Baohui, Li Gang, Shi Fanchao, Niu Xihua, Yang Lin
2022, 38(6): 549-554. doi: 10.3760/cma.j.cn501120-20210419-00134
Abstract:
Objective To investigate the incidence and risk factors of deep venous thrombosis (DVT) of lower extremity in patients with stage Ⅲ and Ⅳ pressure ulcer on admission. Methods A retrospective case series study was conducted. A total of 241 patients with stage Ⅲ and Ⅳ pressure ulcers who met the inclu...
Case Report
A case of chronic refractory wound in the abdomen caused by residual foreign body
Wang Xingang, Yu Chaoheng, Yin Jun, You Chuangang, Zhang Wei, Han Chunmao
2022, 38(6): 555-557. doi: 10.3760/cma.j.cn501120-20210419-00137
Abstract:
A 59-year-old male patient with local sinus tract formation due to residual foreign body was admitted to the Second Affiliated Hospital of Zhejiang University College of Medicine on December 17, 2018. The examination showed that the residual foreign body was the component of a sticky cloth implanted...
Reviews·Autoimmune Diseases Related Wounds
Research advances on the clinical characteristics and diagnosis and treatment of autoimmune disease-related ulcers
Zhao Ling, Su Kaisheng, Ye Zhuang, Jiang Zhenyu, Chen Lu, Long Yu
2022, 38(6): 558-562. doi: 10.3760/cma.j.cn501120-20211019-00358
Abstract:
Studies have shown that autoimmune disease (AID)-related ulcers are disease complications that lead to serious poor prognosis such as infection and disability. It is difficult to make a clear diagnosis and there are contradictions between the applications of immunosuppressive therapy and anti-infect...
Advances on the research and treatment of autoimmune disease-related chronic wounds
Zhang Lu, Wang Xingtong, Chu Wanli
2022, 38(6): 563-568. doi: 10.3760/cma.j.cn501225-20220329-00101
Abstract:
Autoimmune disease is a disease caused by the body's immune system being misdirected to attack the host itself. Patients with this type of diseases are in poor general condition, and are affected by vascular and skin tissue lesions, and therapeutic drugs. Once the skin is broken, chronic wounds that...
Research advances on the pathogenesis and diagnosis of pyoderma gangrenosum
Yang Lan, Yang Qingwen, Fu Yanjie
2022, 38(6): 569-573. doi: 10.3760/cma.j.cn501225-20220331-00117
Abstract:
Pyoderma gangrenosum (PG) is a rare neutrophilic dermatosis, closely associated with the immune system. Its pathogenesis is currently not clear. The lack of specificity in the clinical manifestations and histopathological changes of PG leads to a long clinical diagnosis cycle and even misdiagnosis, ...
Current situation and the latest progress in the treatment of pyoderma gangrenosum
Li Yang, Wang Yuanyuan, Xing Ke, Li Shanshan
2022, 38(6): 574-579. doi: 10.3760/cma.j.cn501225-20220330-00108
Abstract:
Pyoderma gangrenosum (PG) is a rare chronic inflammatory non-infectious skin dermatosis, and there is no clear treatment guideline for this disease at home and abroad. There are a variety of clinical treatment methods for PG, including local therapy and systemic application of glucocorticoids, immun...
Reviews
Research advances on functional training robots in burn rehabilitation
Tian Yafei, Liu Yi
2022, 38(6): 580-584. doi: 10.3760/cma.j.cn501120-20210416-00131
Abstract:
Patients with deep burns are prone to suffer cicatrix hyperplasia or contracture, leading to problems including dysfunction in limbs, which impacts patients' life quality and makes it difficult for them to return to society. Thereby, the rehabilitation treatment after deep burns is particularly impo...
Clinical application and related research advances of negative pressure wound therapy in wound treatment
Ji Chao, Xiao Shichu
2022, 38(6): 585-589. doi: 10.3760/cma.j.cn501120-20210511-00179
Abstract:
Wound repair has always been one of the key issues of clinical concern. In recent years, negative pressure wound therapy (NPWT) has played an increasingly active role in promoting various wound repairs, not only for the treatment of common acute and chronic wounds, but also for closure of surgical i...
Research advances on the characteristics of fibroblast in keloid
Wang Yunzhang, Su Chen, Fu Siqi, Liu Liqiang
2022, 38(6): 590-594. doi: 10.3760/cma.j.cn501120-20210510-00176
Abstract:
In re-cent 20 years, the development of cell biology technology has promoted the research of keloid. Keloid fibroblasts (KFbs) are the main effector cells in keloid, which are closely related to the occurrence and development of keloid. It is significantly different in terms of biological characteri...
Research advances on mesenchymal stem cells and their derivatives in the treatment of acne scars
Li Fang, Cai Yuan, Deng Chengliang
2022, 38(6): 595-600. doi: 10.3760/cma.j.cn501120-20210510-00177
Abstract:
Acne is a common chronic inflammatory disease of the skin that often occurs on the face, and acne scars are often secondary to the healing process of acne, which often leads to impaired appearance and psychological disorders of patients. The current treatment for acne scars is extremely difficult. W...