2023 Vol. 39, No. 7

Academician Forum
Ten key points in the high-quality construction and development of the disciplinary system of wound repair with Chinese characteristics
Fu Xiaobing
2023, 39(7): 601-605. doi: 10.3760/cma.j.cn501225-20230620-00222
Abstract:
Phased major results with construction of the disciplinary system of wound repair with Chinese characteristics have been achieved in the past 30 years. However, some problems in institutional issues still affect the development of the discipline. In this paper, 10 aspects of the impact of discipline...
Expert Forums
Novel strategy of sepsis immunomodulation targeting dendritic cells
Yao Yongming, Zhang Hui, Wu Yao
2023, 39(7): 606-611. doi: 10.3760/cma.j.cn501225-20230321-00087
Abstract:
Dendritic cells (DCs) are the major antigen-presenting cells that play critical roles in regulating both innate and acquire immune responses. In the state of sepsis, the number of DCs is obviously decreased with inhibited antigen presenting ability as well as abnormal cytokine secretion, thereby res...
Strengthening the development and application of precision burn medicine
Luo Gaoxing, Sun Xiaoyan, Wu Jun
2023, 39(7): 612-617. doi: 10.3760/cma.j.cn501225-20230407-00116
Abstract:
In recent years, precision medicine in various clinical disciplines has made great progress. However, the progress and practice of precision medicine in burn surgery at present have lagged far behind other disciplines due to various reasons including the solidification of concepts and the lack of ef...
Original Articles·Infection and Immunity of Burns and Trauma
Analysis of clinical characteristics and risk factors of death in critical burn patients complicated with invasive fungal infection
Li Yanguang, Chang Shuailei, Xie Jiangfan, Ye Xiangyang, Wang Lei, Li Yancang, Li Yun, Li Xiaoliang
2023, 39(7): 618-624. doi: 10.3760/cma.j.cn501225-20230415-00127
Abstract:
Objective To investigate the clinical characteristics and risk factors of critical burn patients complicated with invasive fungal infection. Methods A retrospective case series study was conducted. From January 2017 to December 2022, 88 critical burn patients combined with invasive fungal infectio...
Regulatory effects of the Nocardia rubra cell wall skeleton on the biological function of human neutrophils
Yang Yunxi, Huang Jiamin, Liu Lu, Li Linbin, Zheng Chunfang, Zhou Yuying, Sun Bingwei
2023, 39(7): 625-632. doi: 10.3760/cma.j.cn501225-20230223-00056
Abstract:
Objective To investigate the regulatory effects and mechanism of Nocardia rubra cell wall skeleton (Nr-CWS) on the biological function of human neutrophils. Methods The experimental research method was used. Fifteen healthy adult volunteers (7 males and 8 females, aged 24 to 45 years) were recruit...
Effects of enhancing the expression of aryl hydrocarbon receptor in post-traumatic mice macrophages on the inflammatory cytokine level and bactericidal ability
Kuang Tianyin, Yin Shuangqin, Dai Weihong, Luo Li, Chen Tao, Liang Xinghe, Wang Rixing, Liang Huaping, Zhu Junyu
2023, 39(7): 633-640. doi: 10.3760/cma.j.cn501225-20230210-00040
Abstract:
Objective To explore the expression pattern of aryl hydrocarbon receptor (AhR) in mice peritoneal macrophages (PMs) after major trauma and analyze the effects of enhanced AhR expression on the inflammatory cytokine level and bactericidal ability after trauma. Methods The experimental study method ...
Original Articles
Management strategy of femoral artery pseudoaneurysm combined with infectious wounds
Chu Guoping, Jiang Chaolong, Xuan Tianfan, Zhou Dian, Ding Lingtao, Yang Minlie, Zhao Peng, Zhu Yugang, Lyu Guozhong
2023, 39(7): 641-647. doi: 10.3760/cma.j.cn501225-20221122-00501
Abstract:
Objective To investigate the surgical treatment methods of femoral artery pseudoaneurysm combined with infectious wounds and to evaluate the clinical effects. Methods The retrospective observational research method was used. Twelve patients with femoral artery pseudoaneurysm combined with infectio...
Clinical effects of retrograde anterolateral thigh flaps in repairing anterior knee joint wounds under the concept of precise flap surgery
He Xiaoqing, Yang Xi, Shi Yan, Duan Jiazhang, Dong Kaixuan, Xu Yuexian, Xu Yongqing, Su Yongyue
2023, 39(7): 648-654. doi: 10.3760/cma.j.cn501225-20221020-00461
Abstract:
Objective To introduce the methods of retrograde anterolateral thigh flaps in repairing anterior knee joint wounds under the concept of precise flap surgery and to explore the clinical effects. Methods A retrospective observational study was conducted. From August 2014 to March 2022, 7 patients wi...
Effects of bilobated superficial peroneal artery perforator flap in repairing two adjacent wounds of the fingers
Zhang Tao, Cheng Junnan, Yang Lin, Sun Fengwen, Gao Qinfeng, Huang Yongtao, Yang Chengpeng, Cao Yang, Liu Zhijin, Ju Jihui
2023, 39(7): 655-661. doi: 10.3760/cma.j.cn501225-20220930-00428
Abstract:
Objective To investigate the therapeutic efficacy of bilobated superficial peroneal artery perforator flap in repairing two adjacent wounds of the fingers. Methods A retrospective observational study was conducted. From January 2021 to January 2022, 15 patients with two adjacent wounds of the fing...
Influence of pH value on tube formation of human dermal microvascular endothelial cells and its molecular mechanism
Wang Xiaolin, Li Jing, Bian Yongqian, Li Jinqing, Li Xueyong
2023, 39(7): 662-670. doi: 10.3760/cma.j.cn501225-20220930-00429
Abstract:
Objective To explore the influence of pH value on tube formation of human dermal microvascular endothelial cells (HDMECs) and study its molecular mechanism, so as to provide theoretical basis for the study of promoting angiogenesis in the process of wound healing. Methods The experimental study me...
Summary of the best evidence on exercise for the prevention and treatment of diabetic foot
Guo Qingjiao, Gu Ying, Ouyang Jing, Yu Lihong, Zhang Yizhi, Rao Jiaqin, Luo Shasha, Xu Wanying
2023, 39(7): 671-678. doi: 10.3760/cma.j.cn501225-20220822-00354
Abstract:
Objective To summarize the best evidence on exercise for the prevention and treatment of diabetic foot. Methods A bibliometric approach was used. Systematic searches were carried out to retrieve all the publicly published evidences till July 2022 on exercise for the prevention and treatment of dia...
Review·Infection and Immunity of Burns and Trauma
Research advances of sepsis biomarkers
Zeng Zhuo, Peng Yizhi, Yuan Zhiqiang
2023, 39(7): 679-684. doi: 10.3760/cma.j.cn501225-20230320-00086
Abstract:
Sepsis is a life-threatening condition for patients. Biomarkers can be used for the diagnosis, treatment, and prognostic assessment of sepsis. In recent years, new biomarkers for sepsis have been discovered, and more than 250 biomarkers have been identified so far. The complexity of the sepsis proce...
Reviews
Application and research progress of permissive hypocaloric nutrition in nutritional therapy of severe burns
Fang He, Xia Zhaofan
2023, 39(7): 685-689. doi: 10.3760/cma.j.cn501225-20221010-00445
Abstract:
Nutritional therapy plays an important role in the treatment of severe burns. With the deepening understanding of metabolic patterns and body responses after severe burns, the concepts and measures of nutritional therapy are also constantly developing and improving. Permissive hypocaloric nutrition ...
Research advances on the mechanism and treatment of post-burn pruritus
Chen Mengjia, Zhang Yuanwen
2023, 39(7): 690-694. doi: 10.3760/cma.j.cn501225-20221018-00457
Abstract:
Pruritus is one of the common symptoms after burn injury, which seriously affects the wound healing and quality of life of burn patients, but its diagnosis and treatment are often neglected. The pathophysiological mechanism of post-burn pruritus has not been elucidated, and it is currently believed ...
Research advances on improving the therapeutic efficacy of mesenchymal stem cell-derived exosomes in wound repair
Duan Yuren, Zhao Yuchen, Song Wenyu, Wang Jiaxin, Pei Jie, Wang Xiaobing
2023, 39(7): 695-700. doi: 10.3760/cma.j.cn501225-20220912-00402
Abstract:
How to promote high-quality wound healing is a common problem for plastic surgery and burn physicians. In recent years, numerous animal studies have demonstrated that mesenchymal stem cell-derived exosomes promote wound repair through multiple mechanisms and are promising cell-free therapeutic agent...