2024 Vol. 40, No. 12

Expert Forum
Practice and thinking on the integrated treatment mode for critical burns
Li Xiaojian, Tang Wenbin, Li Shanghua
2024, 40(12): 1101-1106. doi: 10.3760/cma.j.cn501225-20240827-00317
Abstract:
On the basis of further improving the survival rate of patients, the treatment of critical burns should prevent and treat all kinds of serious complications during the rescue process, shorten the time of wound healing, improve the quality of wound healing, and reduce scar hyperplasia and contracture...
Discussion on the clinical practice and mode of treating critical burns in a comprehensive intensive care unit led by burn department
Zhang Pihong, Zhang Yikun, Liang Pengfei
2024, 40(12): 1107-1113. doi: 10.3760/cma.j.cn501225-20240906-00329
Abstract:
At present, although many burn centers and treatment units in China have established burn intensive care units (ICU), due to their limited capacity, the sudden nature of burn accidents, and the gradual transformation of professional burn treatment team, more and more critically burned patients are m...
Original Article · Critical Burns
Establishment and validation of a risk prediction model for pulmonary embolism in severe burn patients
Jiang Shengpan, Gao Xiaoqing, Luan Xiagang, Tan Yiqing
2024, 40(12): 1114-1122. doi: 10.3760/cma.j.cn501225-20240122-00028
Abstract:
Objective To screen the risk factors for pulmonary embolism in severe burn patients, based on which, a risk prediction model was established and validated. Methods This study was a retrospective case series study. The clinical data of 267 severe burn patients who met the inclusion criteria and were ...
Effects of analgesic and sedation management in critical care medicine on patients with severe burns combined with inhalation injuries and the factors affecting tracheal intubation time
Pan Yanyan, Fan Youfen
2024, 40(12): 1123-1131. doi: 10.3760/cma.j.cn501225-20240625-00248
Abstract:
Objective To analyze the effects of analgesic and sedation management in critical care medicine on patients with severe burns combined with inhalation injuries and the factors affecting the tracheal intubation time. Methods The study was a historical controlled study. A total of 157 patients with se...
Effects and underlying mechanism of human adipose mesenchymal stem cells-derived exosomes on acute lung injury in septic mice
Bai Xiaozhi, Tao Ke, Liu Yang, Hao Tong, Zhang Hao, Guan Hao
2024, 40(12): 1132-1142. doi: 10.3760/cma.j.cn501225-20240927-00355
Abstract:
Objective To explore the effects and underlying mechanism of human adipose mesenchymal stem cells (ADSC)-derived exosomes on acute lung injury in septic mice. Methods The study was an experimental study. Human ADSC of passages 4-5 were selected, and exosomes in their supernatant were isolated and ex...
Original Article
Prospective self-controlled clinical trial on the effects of external sutureless on skin incision healing
Chen Zong'an, Yang Yating, Wang Wenbo, Xia Lingling, Liu Wei, Gao Zhen, Wu Xiaoli
2024, 40(12): 1143-1149. doi: 10.3760/cma.j.cn501225-20240206-00051
Abstract:
Objective To compare the impact of whether to apply the external suture after internal suture on skin incision healing. Methods This study was a prospective self-controlled clinical trial. From November 2020 to September 2021, 49 patients who underwent skin resection surgery and met the inclusion cr...
Clinical effects of Meek skin grafting combined with platelet-rich plasma in repairing extensive deep burn wounds
Zhang Ting, Liu Jiaqi, Yang Yunshu, Han Juntao, Hu Dahai, Zheng Zhao
2024, 40(12): 1150-1157. doi: 10.3760/cma.j.cn501225-20231124-00206
Abstract:
Objective To investigate the clinical effects of Meek skin grafting combined with platelet-rich plasma (PRP) in repairing of extensive deep burn wounds. Methods This study was a retrospective observational study. From August 2018 to August 2023, 44 patients who met the inclusion criteria were admitt...
Clinical curative effects of two types of pedicled flaps in repairing the full-thickness electric burn wounds deep to tendon and bone in the knee
Xue Jidong, Liang Yan, Di Haiping, Xing Peipeng, Dong Guoyun, Liang Zhanling, Xia Chengde
2024, 40(12): 1158-1165. doi: 10.3760/cma.j.cn501225-20240419-00143
Abstract:
Objective To compare the clinical curative effects of saphenous artery flap and retrograde anterolateral femoral perforator flap in repairing full-thickness electric burn wounds deep to tendon and bone in the knee. Methods This study was a retrospective observational study. From July 2018 to Februar...
Analysis of biofilm genes and quorum sensing genes of carbapenem resistant Acinetobacter baumannii in the wounds of diabetic foot patients
Xu Jun, Han Xiaocui, He Lu, Feng Shuhong, Sun Dongjian, Cao Chen, Liu Xijiao, Zhang Yanyan, Ding Baixing, Chang Bai
2024, 40(12): 1166-1175. doi: 10.3760/cma.j.cn501225-20240715-00269
Abstract:
Objective To investigate the biofilm genes and quorum sensing genes of carbapenem resistant Acinetobacter baumannii (CRAB) in the wounds of diabetic foot patients. Methods This study was a retrospective observational study. The 233 strains of Acinetobacter baumannii were cultured from 177 inpatients...
Effect of rat platelet-rich plasma gel on autologous adipose-derived mesenchymal stem cells overexpressing glia-derived neurotrophic factor
Cai Weixia, Zheng Zhao, Liu Jiaqi, Liu Yang, Zhang Ting, Ji Peng, Tian Chenyang
2024, 40(12): 1176-1183. doi: 10.3760/cma.j.cn501225-20240408-00126
Abstract:
Objective To investigate the effect of rat platelet-rich plasma (PRP) gel on autologous adipose-derived mesenchymal stem cells (ADSCs) overexpressing glial-derived neurotrophic factor (GDNF). Methods This study was an experimental study. Five adult male Sprague-Dawley rats were used, and the primary...
Long term efficacy of absorbable sutures coated with silver nanoparticles on the suture track of skin incisions in mice
He Feng, Du Juan, Song Yanbiao, Ye Mao, Wei Yandong, Liu Xuelai
2024, 40(12): 1184-1192. doi: 10.3760/cma.j.cn501225-20231007-00104
Abstract:
Objective To explore the long term efficacy of absorbable sutures coated with silver nanoparticles on the suture track of skin incisions in mice. Methods This study was an experimental research. Eighteen half male and half female BALB/c mice aged 10-12 weeks were divided into normal Vicryl suture gr...
Review
Research advances on extracellular vesicles in promoting diabetic wound healing through the regulation of immune microenvironment
Zhou Ziyue, Xu Guangchao, Wang Dali
2024, 40(12): 1193-1198. doi: 10.3760/cma.j.cn501225-20231215-00243
Abstract:
Peripheral neuropathy and poor blood circulation caused by long-term hyperglycemia in patients with diabetes often leads to foot wounds, ulcers, and gangrene, which accompanied by an imbalance in the wound immune microenvironment. Extracellular vesicle (EV) therapy is an emerging biologic treatment ...
Research advances on the role of plant-derived extracellular vesicles in wound repair
Wang Weiqi, Yang Yueting, Su Zhihong, Li Jin, Hu Wenhui, Zhang Peihua
2024, 40(12): 1199-1204. doi: 10.3760/cma.j.cn501225-20240226-00072
Abstract:
Plant-derived extracellular vesicles (EVs) are nanoscale vesicles secreted by plant cells, containing various proteins, lipids, and RNA molecules, which can regulate the information exchange and material transfer between cells, thus are important carriers of cellular communication. Currently, animal...