2024 Vol. 40, No. 4

Expert Forum
Regenerative rehabilitation: the effects of physical factors on regeneration
Wu Jun, Wei Yating
2024, 40(4): 301-306. doi: 10.3760/cma.j.cn501225-20231229-00278
Abstract:
Wound regeneration and repair is one of the primary research fields in burn and wound repair surgery. In recent years, with the continuous advancement of treatment concept and technologies in the field of rehabilitation, the connection between rehabilitation treatment and wound regeneration and repa...
Clinical application of photobiomodulation in trauma repair and medical aesthetics
Yao Min, Zhang Yiqiu
2024, 40(4): 307-313. doi: 10.3760/cma.j.cn501225-20240203-00048
Abstract:
In recent years, with the deepening of researches on the molecular biological mechanisms of photobiomodulation (PBM), PBM has gradually been applied in clinical practice, providing effective treatment methods and approaches for various diseases. Compared with traditional photothermal therapy, PBM ha...
Original Article · Wound Repair and Scar
Effects of applying human umbilical cord mesenchymal stem cell exosomes through different pathways to treat full-thickness skin defect wounds in mice
Wang Hongyu, Ba Te, Zhou Biao, Yan Zengqiang, Wang Ruijia, Liu Lingying
2024, 40(4): 314-322. doi: 10.3760/cma.j.cn501225-20231123-00203
Abstract:
Objective To investigate the effects of human umbilical cord mesenchymal stem cell (hUCMSC) exosomes in the treatment of full-thickness skin defect wounds in mice through local wound application, subcutaneous injection at the wound margin, and tail vein injection, and to explore the optimal administ...
Effects of gelatin methacrylate anhydride hydrogel loaded with small extracellular vesicles derived from human umbilical cord mesenchymal stem cells in the treatment of full-thickness skin defect wounds in mice
Chen Yiqi, Zhou Yingqian, Wei Qian, Xie Xiaoye, Liu Xinzhu, Li Dawei, Shen Chuan'an
2024, 40(4): 323-332. doi: 10.3760/cma.j.cn501225-20231218-00248
Abstract:
Objective To investigate the effects of gelatin methacrylate anhydride (GelMA) hydrogel loaded with small extracellular vesicles derived from human umbilical cord mesenchymal stem cells (hUCMSCs-sEVs) in the treatment of full-thickness skin defect wounds in mice. Methods This study was an experime...
Exploring the causality between intestinal flora and hyperplastic scars of human based on two-sample Mendelian randomization analysis
Chen Wentao, Wang Xiaoxiang, Zheng Wenlian, Zhang Weiqiang, Mao Lujia, Zhuo Jianan, Zhou Sitong, Yang Ronghua
2024, 40(4): 333-341. doi: 10.3760/cma.j.cn501225-20231129-00215
Abstract:
Objective To investigate the causality between intestinal flora and hypertrophic scars (HS) of human. Methods This study was a study based on two-sample Mendelian randomization (TSMR) analysis. The data on intestinal flora ( n=18 473) and HS ( n=208 248) of human were obtained from the genome-wide...
Original Article
A randomized controlled trial on the effect of early eschar dermabrasion combined with antimicrobial soft silicone foam dressing in the treatment of deep partial-thickness burn wounds in children
Shen Yang, He Jun, Liu Junzhang, Zhang Xianfeng, Tan Jie, Tang Wenjun, Yang Hao, Chen Xu, Luo Xingwang
2024, 40(4): 342-347. doi: 10.3760/cma.j.cn501225-20231004-00103
Abstract:
Objective To explore the effect of early eschar dermabrasion combined with antimicrobial soft silicone foam dressing (hereinafter referred to as foam dressing) in treating the deep partial-thickness burn wounds in children. Methods This study was a randomized controlled trial. From June 2021 to De...
Effects of early debridement and conservative eschar removal followed by wound coverage with acellular dermal matrix in the treatment of children with deep burns
Liang Yan, Shi Wen, Shao Yang, Liu Xinzhuang, Gong Hongmin, Cao Guohui, Gao Cong, Xin Naijun, Song Guodong
2024, 40(4): 348-357. doi: 10.3760/cma.j.cn501225-20230720-00010
Abstract:
Objective To explore the effects of early debridement and conservative eschar removal followed by wound coverage with acellular dermal matrix (ADM), i.e., early surgery, in the treatment of children with deep burns. Methods This study was a retrospective cohort study. From January 2017 to December...
Application effects of armor chest straps in patients with sternal dehiscence after repair surgery
Yang Jiao, Wang Ling, Zhang Wanfu, Chen Yang, Guan Hao
2024, 40(4): 358-364. doi: 10.3760/cma.j.cn501225-20230904-00074
Abstract:
Objective To investigate the application effects of armor chest straps in patients with sternal dehiscence after repair surgery. Methods This study was a retrospective cohort study. The 11 patients who were admitted to the First Affiliated Hospital of Air Force Medical University (hereinafter refe...
Clinical effects of early rehabilitation treatment after repair surgery of skin and soft tissue defects accompanied by extensor tendon injury on the back of hand
Zhu Chan, He Lin, He Ting, Liang Ying, Zhang Bowen, Zhao Haiyang, Guan Hao, Yang Xuekang, Hu Dahai, Han Juntao, Liu Jiaqi
2024, 40(4): 365-372. doi: 10.3760/cma.j.cn501225-20230820-00057
Abstract:
Objective To explore the clinical effects of early rehabilitation treatment after repair surgery of skin and soft tissue defects accompanied by extensor tendon injury on the back of hand. Methods This study was a retrospective non-randomized controlled study. From February 2015 to February 2023, 2...
A cross-sectional survey and analysis of influencing factors on the occurrence of post-burn psychological stress disorder in preschool children
Lu Xuelan, Liu Yingping, Liu Yiwei, Diao Jielin, Wang Feng, Zhong Fangyu, He Jiale, Chen Lang
2024, 40(4): 373-379. doi: 10.3760/cma.j.cn501225-20230731-00028
Abstract:
Objective To explore the occurrence and influencing factors of post-burn psychological stress disorder in preschool children. Methods This study was a multi-center cross-sectional survey. From January 2022 to February 2023, 85 preschool children (aged 1 to 6 years) with burns admitted to the Affil...
Effect of salvia miltiorrhiza combined with roxadustat on wound healing of full-thickness skin defects in diabetic rats and its mechanism
Xia Ruyi, Tang Di, Yang Bin
2024, 40(4): 380-388. doi: 10.3760/cma.j.cn501225-20231020-00124
Abstract:
Objective To explore the effect of salvia miltiorrhiza combined with roxadustat on wound healing of full-thickness skin defects in diabetic rats and its mechanism. Methods This study was an experimental study. Twenty male 8-week-old Sprague-Dawley rats were used to successfully establish diabetic ...
Review
Research advances on the role of aerobic glycolysis in skin fibrosis diseases
Zhang Lixia, Hu Dahai
2024, 40(4): 389-394. doi: 10.3760/cma.j.cn501225-20230712-00004
Abstract:
Skin fibrosis diseases mainly include hypertrophic scar, keloid, and systemic sclerosis, etc. The main pathological features are excessive activation of fibroblasts and abnormal deposition of extracellular matrix. In recent years, studies have shown that aerobic glycolysis is closely related to the ...
Research progresses on acute skin failure in children
Yin Xi, Chang Fei, Chen Jie, Gu Lijuan, Ge Yihong, Mao Jiamin
2024, 40(4): 395-400. doi: 10.3760/cma.j.cn501225-20231014-00113
Abstract:
Acute skin failure (ASF) is an inevitable damage to the skin and subcutaneous tissue caused by hemodynamic instability and/or low perfusion. At present, there are some understandings and reports about adult ASF at home and abroad, but there are few reports about children's ASF. This article reviewed...