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Volume 38 Issue 11
Nov.  2022
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Article Navigation >  CHINESE JOURNAL OF BURNS AND WOUNDS  > 2022  >  38(11): 999-1003
Shi CM.To strengthen the basic and translational research of mesenchymal stem cell-based therapy for refractory wounds[J].Chin J Burns Wounds,2022,38(11):999-1003.DOI: 10.3760/cma.j.cn501225-20220913-00405.
Citation: Shi CM.To strengthen the basic and translational research of mesenchymal stem cell-based therapy for refractory wounds[J].Chin J Burns Wounds,2022,38(11):999-1003.DOI: 10.3760/cma.j.cn501225-20220913-00405.
shu

To strengthen the basic and translational research of mesenchymal stem cell-based therapy for refractory wounds

doi: 10.3760/cma.j.cn501225-20220913-00405

  • Institute of Rocket Force Medicine, State Key Laboratory of Trauma, Burns and Combined Injury, Army Medical University, Chongqing 400038, China

Funds:

Key Program of National Natural Science Foundation of China 82030056

  • Received Date: 2022-09-13
    Abstract
  • In recent years, the application of cell-based therapy in the field of refractory wound repair has shown broad prospects, among which the mesenchymal stem cell is the most concerned and widely studied cell type. Despite the rapid development of clinical translational research, the therapeutic effect of cell-based therapy is not consistent, and most clinical trials have not achieved the desired results. Further studies have found that heterogeneity is an important issue that restricts the further development of cell-based therapy and urgently needs to be studied. Based on the research progress of mesenchymal stem cells, in the review, we discuss the current status and challenges of cell-based therapy strategies for refractory wounds.

     

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