2022 Vol. 38, No. 9

Expert Forum
Current situation and reflection of clinical trials in the field of burn medicine in China
Wu Jun, Chen Zhaohong, Wang Yuzhen
2022, 38(9): 799-804. doi: 10.3760/cma.j.cn501120-20210909-00309
Abstract:
Clinical trials are of great significance in formulating guidelines or consensus for the diagnosis and treatment of burns. However, the innate advantages of clinical trials in the field of burn medicine in China have not been translated into evidence-based medical data. Our research group counted th...
Elite Comments
Research on the development of genetically engineered xenogenic porcine skin and its application in the treatment of burn wounds
Duan Hongjie
2022, 38(9): 805-809. doi: 10.3760/cma.j.cn501225-20220419-00146
Abstract:
In the recent years, the shortage of allo-skin sources has resulted in great challenges for salvage of patients with large area severe burns. Although being similar to human skin in construction and function, the clinical application of xenogenic porcine skin in burn wound management is limited due ...
Original Articles·Photoelectric Therapy for Scar
Effects of composite laser technique combined with multipoint microinjection of triamcinolone acetonide in the treatment of hypertrophic scars in burn children
Lei Ying, Tan Jun, Ouyang Huawei, Liu Xiaojia, Yu Yiling
2022, 38(9): 810-815. doi: 10.3760/cma.j.cn501225-20220519-00192
Abstract:
Objective To explore the effects of pulsed dye laser (PDL) and ultra-pulsed fractional carbon dioxide laser (UFCL) combined with multipoint microinjection of triamcinolone acetonide in the treatment of red hypertrophic scar at early stage in burn children. Methods A retrospective cohort before-after...
Clinical effects of ultra-pulsed fractional carbon dioxide laser in the treatment of mild to moderate microstomia after burns
Zhou Biao, Gao Yixuan, Ba Te, Wang Lingfeng, Cao Shengjun, Li Quan, Yan Zengqiang, Wang Hongyu, Huang Ruijuan
2022, 38(9): 816-821. doi: 10.3760/cma.j.cn501225-20220620-00252
Abstract:
Objective To investigate the clinical effects of ultra-pulsed fractional carbon dioxide laser (UFCL) in the treatment of mild to moderate microstomia after burns. Methods A retrospective observational study was conducted on 19 patients with mild to moderate microstomia after burns who were admitted ...
Clinical effects of pulsed dye laser dynamically combined with triamcinolone acetonide in the treatment of keloids
Liu Zhennan, Zhou Yuemin, Liu Ruoxuan, Li Yaling, Li Qing, Zhang Ting, Zhang Shuman
2022, 38(9): 822-829. doi: 10.3760/cma.j.cn501225-20220620-00249
Abstract:
Objective To explore the clinical effects of pulsed dye laser (PDL) dynamically combined with triamcinolone acetonide (TAC) in the treatment of keloids. Methods A retrospectively observational study was conducted. From April 2015 to October 2020, 34 keloid patients (46 keloids) who met the inclusion...
Original Articles
Effects of low-dose photodynamic therapy on the function of human adipose mesenchymal stem cells and its mechanism
Yang Yang, Li Lei, Yang Zengjun, Zheng Mengxue, He Weifeng, Yin Rui
2022, 38(9): 830-838. doi: 10.3760/cma.j.cn501225-20220325-00092
Abstract:
Objective To investigate the effects of low-dose photodynamic therapy on the proliferation, regulation, and secretion functions of human adipose mesenchymal stem cells (ADSCs) and the related mechanism, so as to explore a new method for the repair of chronic wounds. Methods The experimental research...
Effects of collagen type ⅩⅦ α1 on epidermal stem cells in aging skin and the microRNA intervention mechanism
Sun Jiachen, Sun Tianjun, Shen Chuan'an, Zhao Hongqing, Liu Xinzhu, Zhang Yijie
2022, 38(9): 839-848. doi: 10.3760/cma.j.cn501120-20210829-00293
Abstract:
Objective To investigate the expression and function of collagen type ⅩⅦ α1 (COL17α1) in aging mouse skin and its effect on the stemness and proliferation of human epidermal stem cells (ESCs), and to explore the mechanism of related microRNA (miR) in intervening the expression of COL17α1 of human ES...
Reviews
Research advances on the interaction between Pseudomonas aeruginosa bacteriophages and the host
Shi Xi, Zeng Zhuo, Zhang Yiming, Yang Zichen, Peng Yizhi
2022, 38(9): 849-853. doi: 10.3760/cma.j.cn501120-20210929-00338
Abstract:
Pseudomonas aeruginosa is the most common pathogen of burn wound infection. It can encode a variety of virulence factors and is highly pathogenic, which can lead to poor prognosis and high mortality. In order to research a new method to combat Pseudomonas aeruginosa infection, researchers have obser...
Research advances on the role and mechanism of epidermal stem cells in skin wound repair
Shi Zhiyuan, Zhang Bohan, Sun Jiachen, Liu Xinzhu, Shen Chuan'an
2022, 38(9): 854-858. doi: 10.3760/cma.j.cn501120-20211109-00382
Abstract:
Epidermal stem cells play an pivotal role in skin self-renewal, wound repair, and re-epithelialization process. The emergence of new technologies and concepts such as single-cell sequencing and gene knockout further revealed a new mechanism of epidermal stem cells in epidermal self-renewal and wound...
Research advances on the role of acid fibroblast growth factor in promotion of wound healing
Wang Hongtao, Han Juntao, Hu Dahai
2022, 38(9): 859-863. doi: 10.3760/cma.j.cn501120-20210811-00276
Abstract:
Acid fibroblast growth factor (aFGF) is a member of fibroblast growth factors (FGF) family, widely promoting embryonic development, wound healing, vascular regeneration, nerve injury repair, as well as regulating immune metabolism. Many pathophysiological processes, such as inflammation, neovascular...
Research progress of induced pluripotent stem cells in promoting wound healing of diabetic foot ulcers
2022, 38(9): 864-869. doi: 10.3760/cma.j.cn501120-20210630-00230
Abstract:
Chronic wounds such as diabetic foot ulcers are epidemic, which bring huge burdens to both the patients and the society. However, with current treatment methods, diabetic foot ulcers often heal poorly and recur frequently, so it is urgent and important to find new and advanced therapies. Stem cell t...
Research progress of infrared light promoting wound healing
Zhao Juan, Shu Qing, Jia Shaohui, Tian Jun
2022, 38(9): 870-873. doi: 10.3760/cma.j.cn501120-20211028-00371
Abstract:
At present, current stimulation, ultra-sound, and light therapy have become effective methods to promote wound healing. Among them, infrared light is the most widely used method and is one of the important methods to promote wound healing. The therapeutic effect of infrared light on wounds is relate...
Research advances on interleukin-6 in hypertrophic scar formation
Chen Zuhan, Yu Bin, Ye Qifa, Wang Yanfeng
2022, 38(9): 874-877. doi: 10.3760/cma.j.cn501120-20210331-00111
Abstract:
Hypertrophic scar is a pathological repair result of excessive accumulation of extracellular matrix after skin damage, which affects the appearance and function of patients with varying degrees. The degree of scar formation is directly related to the strength of inflammatory reaction during wound he...
Research advances on the treatment of hydrofluoric acid burns
Mao Shulei, Zhang Yuanhai, Wu Junmei, Ye Chunjiang, Ni Liangfang, Wang Xingang, Wang Rongjuan, Zhang Jianfen
2022, 38(9): 878-882. doi: 10.3760/cma.j.cn501120-20210623-00224
Abstract:
Hydrofluoric acid is a highly dangerous and toxic inorganic acid, which is widely used in industrial fields and daily life. The risk of hydrofluoric acid burns is related to hydrofluoric acid mass fraction, duration of exposure to hydrofluoric acid, burn area, burn depth, and burn site, etc. Hydrofl...
Research advances on influencing factors and intervention strategies of pediatric burns
Hu Jiao, Li Ling, Chen Wei
2022, 38(9): 883-886. doi: 10.3760/cma.j.cn501120-20210830-00295
Abstract:
Burns not only affect children's physiology and psychology, but also bring a burden to their families and society, which can be prevented to a large extent. By introducing the epidemiological characteristics and current disease burden of pediatric burns, and combining them with the Haddon matrix, th...
Research advances on the function of skin touch receptor Merkel cells
Yuan Huipu, Ding Yuanyuan, Zheng Yixin, Zhang Yajun, Liu Xia, Rui Chen, Wang Chaochen, Xiao Ying
2022, 38(9): 887-892. doi: 10.3760/cma.j.cn501120-20211209-00409
Abstract:
The reconstruction of tactile function during the repair of skin damage caused by factors including burns is inseparable from the functional regeneration of tactile receptor Merkel cells. Merkel cells mainly exist in the basal layer of the epidermis and are closely connected with nerves to form Merk...
Research advances on the role of hemoglobin spray in chronic wounds
He Ting, Yuan Li, Yang Xiaoling
2022, 38(9): 892-896. doi: 10.3760/cma.j.cn501120-20210727-00261
Abstract:
Oxygen plays an important role in the process of wound healing. Researches have shown that more than 97% of chronic wounds are in a state of hypoxia, which is one of the key factors resulting in refractory wounds. Local oxygen therapy is a treatment method that can directly provide oxygen to wounds ...
Academic Information
Summary of the 17th Chinese Symposium on Burn Medicine and the 2022 Congress of Burn Medicine Branch of China International Exchange and Promotion Association for Medical and Healthcare, and the 12th Academic Conference on Burn and Plastic Surgery in Five Provinces and One City in Southwest China
Ding Huarong, Jia Jinjin, Mo Yu, He Weifeng, Luo Gaoxing, Li Dehui, Liang Guangping
2022, 38(9): 897-898. doi: 10.3760/cma.j.cn501225-20220912-00404
Abstract:
The 17th Chinese Symposium on Burn Medicine and the 2022 Congress of Burn Medicine Branch of China International Exchange and Promotion Association for Medical and Healthcare, and the 12th Academic Conference on Burn and Plastic Surgery in Five Provinces and One City in Southwest China was successfu...