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美容手术相关非结核分枝杆菌感染的诊断和治疗效果

郭晶东 陈波 彭靓 张冬梅 侯海鑫 李万同 朱雄翔

郭晶东, 陈波, 彭靓, 等. 美容手术相关非结核分枝杆菌感染的诊断和治疗效果[J]. 中华烧伤与创面修复杂志, 2024, 40(7): 1-6. DOI: 10.3760/cma.j.cn501225-20231031-00160.
引用本文: 郭晶东, 陈波, 彭靓, 等. 美容手术相关非结核分枝杆菌感染的诊断和治疗效果[J]. 中华烧伤与创面修复杂志, 2024, 40(7): 1-6. DOI: 10.3760/cma.j.cn501225-20231031-00160.
Guo Jingdong,Chen Bo,Peng Liang,et al.Diagnosis and treatment effect of nontuberculous mycobacteria infections related to cosmetic surgery[J].Chin J Burns Wounds,2024,40(7):1-6.DOI: 10.3760/cma.j.cn501225-20231031-00160.
Citation: Guo Jingdong,Chen Bo,Peng Liang,et al.Diagnosis and treatment effect of nontuberculous mycobacteria infections related to cosmetic surgery[J].Chin J Burns Wounds,2024,40(7):1-6.DOI: 10.3760/cma.j.cn501225-20231031-00160.

美容手术相关非结核分枝杆菌感染的诊断和治疗效果

doi: 10.3760/cma.j.cn501225-20231031-00160
基金项目: 

广东省医学科研基金 B2022034

详细信息
    通讯作者:

    朱雄翔,Email:13991978530@163.com

Diagnosis and treatment effect of nontuberculous mycobacteria infections related to cosmetic surgery

Funds: 

Medical Scientific Research Foundation of Guangdong Province of China B2022034

More Information
  • 摘要:   目的  探讨美容手术相关非结核分枝杆菌(NTM)感染的诊断和治疗效果。  方法  该研究为回顾性观察性研究。2015年1月至2023年12月,南方医科大学深圳医院和北部战区总医院收治符合入选标准的美容手术相关NTM感染患者24例,均为女性,年龄29~51岁,其中行溶脂针注射术者20例、面部线雕手术者2例、异物注射者1例、除皱手术者1例。NTM导致感染的临床表现:感染部位有散在暗紫红色皮下结节且边界不清,结节表面皮肤变薄伴破溃,破溃口可见粉白色鱼肉样组织及和少量淡黄色渗出液。对感染部位行损伤控制性清创,并根据药物敏感试验结果进行包括使用抗生素在内的综合治疗。统计患者感染NTM的亚型及药物敏感试验结果、创面愈合时间及其间样本的细菌培养次数和手术的清创次数。随访,观察创面愈合情况。  结果  细菌培养结果显示,感染脓肿分枝杆菌者23例、偶发分枝杆菌者2例。药物敏感试验结果显示,本研究中的NTM对克拉霉素、阿米卡星、多西环素及利福平等抗生素敏感。创面平均愈合时间为83.6 d,其间对标本进行平均2.85次细菌培养,行清创术的平均次数为2.52次。随访6个月~5年,患者创面全部愈合,其中22例患者外观基本正常,遗留轻微瘢痕;3例患者遗留明显瘢痕及凹陷。  结论  美容手术相关NTM感染的治疗困难,对感染部位进行损伤控制性清创能保证创面愈合的同时减少对面部等美容部位的损伤及术后畸形。

     

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  • 图  1  面部线雕术手术后非结核分枝杆菌引发感染的治疗效果。1A.美容术后1个月,左眶下部红肿;1B.美容术后2个月,左眶下脓肿再发伴破溃;1C:美容术后5个月,左颞部及面颊颧弓处出现散在脓肿;1D.美容术后8个月,左侧面颊靠近下颌缘处出现脓肿;1E.最后1次手术后1年随访,创面愈合良好

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出版历程
  • 收稿日期:  2023-10-31
  • 网络出版日期:  2024-07-08

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