低温大气压等离子体促进创面愈合的作用机制及临床应用研究进展

赵子越; 蔡程浩; 柳欢; 刘舒雯; 王新刚

doi:10.3760/cma.j.cn501225-20241117-00448

低温大气压等离子体促进创面愈合的作用机制及临床应用研究进展

doi: 10.3760/cma.j.cn501225-20241117-00448

浙江大学医学院附属第二医院烧伤与创面修复科，杭州 310009

基金项目:

国家重点研发计划项目 2022YFC2403100

国家自然科学基金面上项目 82172198

浙江省医药卫生科技计划项目 2020KY786

详细信息

通讯作者:
王新刚，Email：wangxingang8157@zju.edu.cn

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出版历程
- 收稿日期: 2024-11-17

Research advances on the mechanism and clinical application of cold atmospheric plasma in promoting wound healing

Department of Burns and Wound Repair, the Second Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou 310009, China

Funds:

National Key Research and Development Program of China 2022YFC2403100

General Program of National Natural Science Foundation of China 82172198

Zhejiang Provincial Medical and Health Science and Technology Program 2020KY786

More Information

Corresponding author: Wang Xingang, Email: wangxingang8157@zju.edu.cn

摘要

摘要: 创面愈合是一个复杂的生物学过程，涉及多个阶段，包括止血、炎症、增殖和重塑。低温大气压等离子体（CAP）作为创面护理的一种高效、非侵入性的创新型疗法，在创面护理领域极具应用前景。研究表明，CAP可通过多种机制促进创面细胞增殖、降低创面的微生物负荷。通过综合分析国内外近年来关于CAP的生物学作用的文献，该文从作用机制和临床应用的角度综述了CAP如何促进急慢性创面的修复，以及近年来CAP在应用方式上的研究进展。
- 伤口愈合 /
- 皮肤 /
- 细胞增殖 /
- 创面护理 /
- 低温大气压等离子体
Abstract: Wound healing is a complex biological process involving multiple stages, including hemostasis, inflammation, proliferation, and remodeling. Cold atmospheric plasma (CAP), as an efficient, non-invasive, and innovative therapy for wound care, has significant application prospects in this field. It has been demonstrated that CAP can promote wound cell proliferation and reduce microbial load on wounds through various mechanisms. Through a comprehensive analysis of recent domestic and international literature on the biological effects of CAP, this paper reviews how CAP promotes the repair of acute and chronic wounds from the perspectives of mechanism and clinical application and the research progress in the application methods of CAP in recent years.
- Wound healing /
- Skin /
- Cell proliferation /
- Wound care /
- Cold atmospheric plasma

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参考文献(48)

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