骨水泥在糖尿病创面治疗中的应用专家共识（2026版）

中国老年医学学会烧创伤分会

doi:10.3760/cma.j.cn501225-20260128-00052

骨水泥在糖尿病创面治疗中的应用专家共识（2026版）

doi: 10.3760/cma.j.cn501225-20260128-00052

中国老年医学学会烧创伤分会

基金项目:

国家自然科学基金面上项目 82272269

详细信息

通信作者：陶克,温州医科大学附属第一医院创面修复与再生医学中心创面修复科,温州 325000,Email：tao-ke2001@163.com郭光华,南昌大学第一附属医院烧伤整形与创面修复医学中心,南昌 330006,Email：guogh2000@hotmail.com付小兵,解放军总医院医学创新研究部创伤修复与组织再生重点实验室,北京 100853,Email：fuxiaobing@vip.sina.com

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出版历程
- 收稿日期: 2026-01-28
- 网络出版日期: 2026-08-03

Expert consensus on the application of bone cement in the treatment of diabetic wounds (2026 edition)

Funds:

General Program of National Natural Science Foundation of China 82272269

摘要

摘要: 包括糖尿病溃疡在内的糖尿病创面是糖尿病晚期的严重并发症之一,其病情发展迅速、治疗困难、常导致截肢,甚至危及生命。目前治疗原则是在改善肢体血运的基础上,结合负压引流、换药及用肌瓣、皮瓣、皮肤及人工皮肤组织覆盖等外科手段消除创面。近年来,应用骨水泥初步处理糖尿病创面,再联合植皮或皮瓣移植覆盖创面的疗法已有较多文献报道。为了进一步规范骨水泥在糖尿病创面治疗中的应用,由中国老年医学学会烧创伤分会牵头的专家组共同审议并编写了《骨水泥在糖尿病创面治疗中的应用专家共识（2026版）》。该共识以文献证据为基础,结合最新的临床及基础研究进展,旨在形成骨水泥治疗糖尿病创面的规范化方案,供医师参考,提升糖尿病创面的临床诊疗水平。
- 糖尿病 /
- 临床方案 /
- 慢性创面 /
- 骨水泥 /
- 创面愈合
Abstract: Diabetic wounds, including diabetic ulcers, represent one of the most severe late-stage complications of diabetes mellitus, characterized by rapid progression, therapeutic challenges, and high risks of amputation or life-threatening consequences. The current treatment principle is to eliminate the wound surface by means of negative pressure suction, dressing changes, and coverage with muscle flaps, skin flaps, autologous skin, and artificial skin tissues, based on improving the blood supply of the limb. In recent years, emerging evidence has highlighted the efficacy of bone cement-based preliminary management for diabetic wounds, followed by skin or flap transplantation for definitive wound coverage. To standardize clinical practices, the Burn and Trauma Branch of Chinese Geriatrics Society jointly organized an expert panel to develop the Expert consensus on the application of bone cement in diabetic wound management (2026 edition). This consensus integrates robust evidence from literature with cutting-edge clinical and basic research advancements, aiming to establish a standardized protocol for bone cement utilization in diabetic wound therapy. It serves as a critical reference for clinicians to enhance diagnostic and therapeutic outcomes in diabetic wound care.
- Diabetes mellitus /
- Clinical protocols /
- Chronic wounds /
- Bone cement /
- Wound healing
所有编写组成员在共识启动前都签署了《利益冲突声明书》,声明不存在与本共识主题直接相关的商业利益冲突。无商业组织向本共识编写组支付费用,本共识制订过程中需要的资金均来自本文著录的基金项目,用以承担制订过程中的材料费、查新费、差旅费及项目组织实施费用等,且推荐意见未受资助影响

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图 1 骨水泥在糖尿病创面治疗中的操作流程示意图

注：最左侧图中的抗生素不是必选项

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图 2 《骨水泥在糖尿病创面治疗中的应用专家共识（2026版）》临床路径图

《骨水泥在糖尿病创面治疗中的应用专家共识（2026版）》编写组

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Table 1. 2011版牛津大学循证医学中心证据等级标准

证据等级	定义
1级	基于随机对照试验或单人交叉临床试验的系统性文献回顾,对随机性研究的系统综述
2级	随机对照试验或效果显著的观察性研究
3级	非随机性、对照性队列研究或随访研究
4级	病例系列、病例对照研究或历史对照研究
5级	基于机制的推论