Abstract: Graphene, as a new two-dimensional nanomaterial, is isolated and prepared for various industries application, which has become a hot research topic at present. It is also used in biomedicine for drug carriers, biological detection, cancer treatment, and tissue engineering. Graphene and its derivatives have great potential in the application of wound dressings attributed to the unique and good properties, including self-antibacterial property and antibacterial property in combination with different substances, excellent mechanical property, biocompatibility, etc. This article reviews the research of graphene and its derivatives in wound dressings.