2023 Vol. 39, No. 1

2023, 39(1): 1-4. doi: 10.3760/cma.j.cn501225-20220111-00002
Abstract:
Establishment and application of the ten-fold rehydration formula for emergency resuscitation of pediatric patients after extensive burns
Shen Chuan'an, Liu Xinzhu, Xie Xiaoye, Zhang Bohan, Li Dawei, Liu Zhaoxing, Yuan Huageng
2023, 39(1): 59-64. doi: 10.3760/cma.j.cn501120-20211111-00384
Abstract:
Objective To investigate the scientificity and feasibility of the ten-fold rehydration formula for emergency resuscitation of pediatric patients after extensive burns. Methods A retrospective observational study was conducted. The total burn area of 30%-100% total body surface area (TBSA) and body w...
Academician Forum
Continue to promote the construction of the discipline system of wound repair with Chinese characteristics
Fu Xiaobing
2023, 39(1): 5-8. doi: 10.3760/cma.j.cn501225-20230106-00005
Abstract:
The repair of various kinds of complex and difficult-to-heal wounds is a major national demand for disease treatment in new era. Since the National Health Commission approved the establishment of wound repair departments in medical institutions with suitable condition at all levels in 2019, remarkab...
Expert Forums
Role of functional hydrogel in promoting wound healing
Luo Gaoxing, Lu Yifei, Huang Can
2023, 39(1): 9-14. doi: 10.3760/cma.j.cn501225-20221123-00503
Abstract:
Cutaneous wounds are one of the commonest clinical diseases. At present, there are still many challenges in how to repair wounds quickly with high quality. With the rapid development and cross-integration of materials science and biomedicine, hydrogels that can integrate various excellent properties...
Original Articles·Application of Biological Materials in Wound Repair
Effects of interleukin-4-modified gold nanozymes on the full-thickness skin defects in diabetic mice
Yao Mengyun, Zhang Ning, Zhang Qing, Lu Yifei, Huang Yong, He Dengfeng, Chen Yunxia, Luo Gaoxing
2023, 39(1): 15-24. doi: 10.3760/cma.j.cn501225-20220630-00275
Abstract:
Objective To investigate the effects and mechanism of interleukin-4-modified gold nanoparticle (IL-4-AuNP) on the wound healing of full-thickness skin defects in diabetic mice. Methods Experimental research methods were adopted. Gold nanoparticle (AuNP) and IL-4-AuNP were synthesized by improving th...
Effects of porcine urinary bladder matrix on motility and polarization of bone marrow-derived macrophages in mice
Tang Xiaoyu, Liu Chenyang, Chu Guoping, Li Xiaoxiao, Hu Kai, Zhao Peng, Lyu Guozhong
2023, 39(1): 25-34. doi: 10.3760/cma.j.cn501225-20220516-00187
Abstract:
Objective To explore the effects of porcine urinary bladder matrix (UBM) on the motility and polarization of bone marrow-derived macrophages in mice, so as to provide evidence for the rational selection of stent in clinical wound repair. Methods The method of experimental research was used. The micr...
Influence of reactive oxygen species responsive self-assembled nanomicelle loaded with pyroptosis inhibitor on full-thickness skin defects in diabetic rats
Ou Zelin, Wang Jue, Shi Rong, Deng Jun, Liu Yi, Luo Gaoxing
2023, 39(1): 35-44. doi: 10.3760/cma.j.cn501225-20221109-00483
Abstract:
Objective To investigate the influence of reactive oxygen species (ROS) responsive self-assembled nanomicelle loaded with pyroptosis inhibitor on full-thickness skin defects in diabetic rats. Methods Experimental research methods were employed. A nucleotide-binding oligomerization domain (NOD) 1/2 i...
Original Articles
Exploration of family rehabilitation model for children with scar contracture after hand burns
Zhu Chan, He Lin, Zhang Bowen, Liang Ying, Zhao Haiyang, Qi Zongshi, Liang Min, Han Juntao, Hu Dahai, Liu Jiaqi
2023, 39(1): 45-52. doi: 10.3760/cma.j.cn501225-20220622-00253
Abstract:
Objective To explore the family rehabilitation model for children with scar contracture after hand burns and observe its efficacy. Methods A retrospective non-randomized controlled study was conducted. From March 2020 to March 2021, 30 children with scar contracture after deep partial-thickness to f...
Clinical effects of fractional carbon dioxide laser combined with minimally invasive scar release in the treatment of post-acne atrophic scars
Ge Yanna, Pan Huanhuan, Zhao Jiangbo, Chen Ya
2023, 39(1): 53-58. doi: 10.3760/cma.j.cn501225-20220616-00238
Abstract:
Objective To explore the clinical effects of fractional carbon dioxide laser combined with minimally invasive scar release in the treatment of post-acne atrophic scars. Methods A retrospectively observational study was conducted. From January to June 2021, 60 patients with grade 3 and 4 post-acne at...
Wound Repair
Clinical effects of island posterior femoral composite tissue flaps in the repair of sinus cavity pressure ulcers in the areas of ischial tuberosity and greater trochanter
Zhou Xiaoliang, Tu Jiajin, Ye Hua, Wang Xianlin, Sun Junfeng, Long Liyun, Ding Yumei
2023, 39(1): 65-70. doi: 10.3760/cma.j.cn501225-20220420-00148
Abstract:
Objective To explore the clinical effects of island posterior femoral composite tissue flaps in the repair of sinus cavity pressure ulcers in the areas of ischial tuberosity and greater trochanter. Methods The retrospective observational study was conducted. From December 2018 to December 2021, 23 p...
Case Report and Literature Review
A case of skin ulcers secondary to extensive burns caused by flame and heavy metal-containing hydrothermal fluids
Dong Hongfei, Huang Xi, Wu Jiyou, Li Xianhui
2023, 39(1): 71-74. doi: 10.3760/cma.j.cn501120-20211115-00386
Abstract:
On May 13, 2020, a 56-year-old man with extensive burns caused by flames and heavy metal-containing hydrothermal fluids was admitted to the General Hospital of Western Theater Command. After being admitted to the hospital, most of the burn wounds healed after treatments such as debridement, expansio...
Reviews
Research advances of various omics analyses in chronic refractory wounds on body surface
Zeng Shuaidan, Yang Lei
2023, 39(1): 75-80. doi: 10.3760/cma.j.cn501225-20220216-00030
Abstract:
The diagnosis and treatment of chronic refractory wounds on body surface has always been full of challenges, and it also poses a huge burden on medical care and society. High-throughput sequencing combined with omics analysis can reveal potential mechanisms of chronic wound formation, and identify p...
Research advances of adipose stem cell matrix gel in promoting wound healing
Xing Nan, Huo Ran, Wang Haitao, Yang Jincun, Chen Jiong, Peng Lei, Liu Xiaowen
2023, 39(1): 81-84. doi: 10.3760/cma.j.cn501120-20211204-00404
Abstract:
In recent years, with the problem of aging population in China being prominant, the number of patients with chronic wounds such as diabetic foot, pressure ulcer, and vascular ulcer is increasing. Those diseases seriously affect the life quality of patients and increase the economy and care burden of...
Research advances on the mechanism of extracellular vesicles of adipose-derived mesenchymal stem cells in promoting wound angiogenesis
Ju Yikun, Fang Bairong
2023, 39(1): 85-90. doi: 10.3760/cma.j.cn501225-20220322-00080
Abstract:
Wound healing involves complex pathophysiological mechanism, among which angiogenesis is considered as one of the key steps in wound healing, and promoting wound angiogenesis can accelerate wound healing. In recent years, mesenchymal stem cell-derived extracellular vesicles have been proven to produ...
Research advances on the role of nuclear factor-erythroid 2-related factor 2 in wound healing
Guo Jia, Zhang Junxia
2023, 39(1): 91-95. doi: 10.3760/cma.j.cn501225-20220531-00209
Abstract:
Wound healing is one of the common pathophysiological processes in the body. How to improve the condition of wound healing to promote rapid wound healing has always been a hotspot in research. Oxidative stress is one of the important factors affecting wound healing. Nuclear factor-erythroid 2-relate...
Research progress on moderate and deep sedation during wound dressing change in pediatric burn patients
Feng Huali, Wang Sha, Xiang Qin, Xu Caijuan, Zhong Yu, Zheng Xinxin, You Min, Lan Lan
2023, 39(1): 96-104. doi: 10.3760/cma.j.cn501225-20220421-00153
Abstract:
Moderate and deep sedation can effectively relieve or eliminate the pain and body discomfort during wound dressing change in pediatric burn patients, relieve anxiety, agitation, and even delirium of the children, reduce the metabolic rate of the children, make them in a quiet, comfortable, and coope...